Ajax E. George
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View article: Early life outcomes of prenatal exposure to alcohol and synthetic cannabinoids in mice
Early life outcomes of prenatal exposure to alcohol and synthetic cannabinoids in mice Open
View article: Early Life Outcomes of Prenatal Exposure to Alcohol and Synthetic Cannabinoids in Mice
Early Life Outcomes of Prenatal Exposure to Alcohol and Synthetic Cannabinoids in Mice Open
This study explores the effects of prenatal co-exposure to alcohol and synthetic cannabinoids on offspring viability, physical development, and neurobehavioral outcomes in young adulthood. The aim is to identify distinct outcomes of co-exp…
View article: Ki-67 With MRI in Predicting the Complete Pathological Response Post-neoadjuvant Chemotherapy
Ki-67 With MRI in Predicting the Complete Pathological Response Post-neoadjuvant Chemotherapy Open
View article: Evaluating the Diagnostic Potential of Four-Dimensional Flow Magnetic Resonance Imaging in Aortic Stenosis Diagnosis: A Systematic Review and Meta-Analysis
Evaluating the Diagnostic Potential of Four-Dimensional Flow Magnetic Resonance Imaging in Aortic Stenosis Diagnosis: A Systematic Review and Meta-Analysis Open
This systematic review and meta-analysis evaluates the potential of four-dimensional flow magnetic resonance imaging (4DFM) in assessing aortic stenosis (AS) compared to traditional imaging modalities like two-dimensional phase contrast MR…
View article: Retrospective analysis of Braak stage– and APOE4 allele–dependent associations between MR spectroscopy and markers of tau and neurodegeneration in cognitively unimpaired elderly
Retrospective analysis of Braak stage– and APOE4 allele–dependent associations between MR spectroscopy and markers of tau and neurodegeneration in cognitively unimpaired elderly Open
View article: Using synchronized brain rhythms to bias memory-guided decisions
Using synchronized brain rhythms to bias memory-guided decisions Open
Functional interactions between the prefrontal cortex and hippocampus, as revealed by strong oscillatory synchronization in the theta (6-11 Hz) frequency range, correlate with memory-guided decision-making. However, the degree to which thi…
View article: Reviewer #1 (Public Review): Using synchronized brain rhythms to bias memory-guided decisions
Reviewer #1 (Public Review): Using synchronized brain rhythms to bias memory-guided decisions Open
Functional interactions between the prefrontal cortex and hippocampus, as revealed by strong oscillatory synchronization in the theta (6-11 Hz) frequency range, correlate with memory-guided decision-making. However, the degree to which thi…
View article: Using synchronized brain rhythms to bias memory-guided decisions
Using synchronized brain rhythms to bias memory-guided decisions Open
Functional interactions between the prefrontal cortex and hippocampus, as revealed by strong oscillatory synchronization in the theta (6-11 Hz) frequency range, correlate with memory-guided decision-making. However, the degree to which thi…
View article: Deep Learning Achieves Neuroradiologist-Level Performance in Detecting Hydrocephalus Requiring Treatment
Deep Learning Achieves Neuroradiologist-Level Performance in Detecting Hydrocephalus Requiring Treatment Open
View article: Larger hippocampal and brainstem volumes in high volume lumbar puncture responders as a predictor of shunt response in normal pressure hydrocephalus
Larger hippocampal and brainstem volumes in high volume lumbar puncture responders as a predictor of shunt response in normal pressure hydrocephalus Open
Background Normal pressure hydrocephalus (NPH) is a treatable cause of dementia, urinary incontinence and gait abnormality which is important to diagnose early as the longer the delay in treatment, the worse the outcome after shunting. Gai…
View article: Deep Learning Achieves Neuroradiologist-Level Performance in Detecting Hydrocephalus Requiring Treatment
Deep Learning Achieves Neuroradiologist-Level Performance in Detecting Hydrocephalus Requiring Treatment Open
Purpose In large clinical centers a small subset of patients present with hydrocephalus that requires surgical treatment. We aimed to develop a screening tool to detect such cases from the head MRI with performance comparable to neuroradio…
View article: Diffusional Kurtosis along the Corticospinal Tract in Adult Normal Pressure Hydrocephalus
Diffusional Kurtosis along the Corticospinal Tract in Adult Normal Pressure Hydrocephalus Open
A lower axonal water fraction indicates a lower axonal density in the corticospinal tract, which may indicate permanent damage. Lower axial kurtosis may imply that axons are being more aligned due to compression.
View article: <i>Reply:</i>
<i>Reply:</i> Open
We thank Onder and Hanalioglu for their comments on our article, “Lumbar Puncture Test in Normal Pressure Hydrocephalus: Does the Volume of CSF Removed Affect the Response to Tap?” Our work, though retrospective, casts doubt on the use of …
View article: Diagnosis of Normal-Pressure Hydrocephalus: Use of Traditional Measures in the Era of Volumetric MR Imaging
Diagnosis of Normal-Pressure Hydrocephalus: Use of Traditional Measures in the Era of Volumetric MR Imaging Open
Purpose To assess the diagnostic performance of the callosal angle (CA) and Evans index (EI) measures and to determine their role versus automated volumetric methods in clinical radiology. Materials and Methods Magnetic resonance (MR) exam…
View article: Lumbar Puncture Test in Normal Pressure Hydrocephalus: Does the Volume of CSF Removed Affect the Response to Tap?
Lumbar Puncture Test in Normal Pressure Hydrocephalus: Does the Volume of CSF Removed Affect the Response to Tap? Open
We found no evidence to support that a higher volume of CSF removal impacts gait testing, suggesting that a high volume of CSF removal may not be necessary in a diagnostic lumbar tap test.
View article: Motor planning poststroke: impairment in vector-coded reach plans
Motor planning poststroke: impairment in vector-coded reach plans Open
Healthy individuals appear to use both vector-coded reach plans that encode movements in terms of their desired direction and extent, and target-coded reach plans that encode the desired endpoint position of the effector. We examined wheth…
View article: Early glial activation precedes neurodegeneration in the cerebral cortex after <scp>SIV</scp> infection: <scp>A 3D</scp>, multivoxel proton magnetic resonance spectroscopy study
Early glial activation precedes neurodegeneration in the cerebral cortex after <span>SIV</span> infection: <span>A 3D</span>, multivoxel proton magnetic resonance spectroscopy study Open
Objectives As ∼40% of HIV ‐infected individuals experience neurocognitive decline, we investigated whether proton magnetic resonance spectroscopic imaging ( 1 H ‐ MRSI ) detects early metabolic abnormalities in the cerebral cortex of a sim…