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View article: Methicillin-resistant <i>Staphylococcus aureus</i> bacteremia with elevated vancomycin minimum inhibitory concentrations
Methicillin-resistant <i>Staphylococcus aureus</i> bacteremia with elevated vancomycin minimum inhibitory concentrations Open
This case–control study of 25 cases with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia with vancomycin minimum inhibitory concentration (MIC) ≥ 2 µg/mL and 391 controls (MIC < 2 µg/mL) characterized the clinical characteris…
View article: Everybody nose: molecular and clinical characteristics of nasal colonization during active methicillin-resistant Staphylococcus aureus bloodstream infection
Everybody nose: molecular and clinical characteristics of nasal colonization during active methicillin-resistant Staphylococcus aureus bloodstream infection Open
Background Healthcare-associated infections pose a potentially fatal threat to patients worldwide and Staphylococcus aureus is one of the most common causes of healthcare-associated infections. S. aureus is a common commensal pathogen and …
View article: Additional file 1 of Everybody nose: molecular and clinical characteristics of nasal colonization during active methicillin-resistant Staphylococcus aureus bloodstream infection
Additional file 1 of Everybody nose: molecular and clinical characteristics of nasal colonization during active methicillin-resistant Staphylococcus aureus bloodstream infection Open
Additional file 1: Table S1. MRSA isolate typing.
View article: Robust clinical detection of SARS‐CoV‐2 variants by RT‐PCR/MALDI‐TOF multitarget approach
Robust clinical detection of SARS‐CoV‐2 variants by RT‐PCR/MALDI‐TOF multitarget approach Open
The coronavirus disease 2019 (COVID‐19) pandemic has sparked the rapid development of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) diagnostics. However, emerging variants pose the risk for target dropout and false‐negative …
View article: Everybody Nose: Molecular and Clinical Characteristics of Nasal Colonization During Active Methicillin-Resistant Staphylococcus Aureus Bloodstream Infection
Everybody Nose: Molecular and Clinical Characteristics of Nasal Colonization During Active Methicillin-Resistant Staphylococcus Aureus Bloodstream Infection Open
View article: Robust clinical detection of SARS-CoV-2 variants by RT-PCR/MALDI-TOF multi-target approach
Robust clinical detection of SARS-CoV-2 variants by RT-PCR/MALDI-TOF multi-target approach Open
The COVID-19 pandemic sparked rapid development of SARS-CoV-2 diagnostics. However, emerging variants pose the risk for target dropout and false-negative results secondary to primer/probe binding site (PBS) mismatches. The Agena MassARRAY …
View article: Modified methicillin-resistant <i>Staphylococcus aureus</i> detected in neonatal intensive care patients
Modified methicillin-resistant <i>Staphylococcus aureus</i> detected in neonatal intensive care patients Open
Objectives As part of an active MRSA surveillance programme in our neonatal ICU, we identified nares surveillance cultures from two infants that displayed heterogeneity in methicillin resistance between isolated subclones that lacked mecA …
View article: Molecular evidence of SARS-CoV-2 in New York before the first pandemic wave
Molecular evidence of SARS-CoV-2 in New York before the first pandemic wave Open
View article: Deciphering the introduction and transmission of SARS-CoV-2 in the Colombian Amazon Basin
Deciphering the introduction and transmission of SARS-CoV-2 in the Colombian Amazon Basin Open
Background The SARS-CoV-2 pandemic has forced health authorities across the world to take important decisions to curtail its spread. Genomic epidemiology has emerged as a valuable tool to understand introductions and spread of the virus in…
View article: Modified Oxacillin Resistant <i>Staphylococcus aureus</i> detected in neonatal intensive care patients
Modified Oxacillin Resistant <i>Staphylococcus aureus</i> detected in neonatal intensive care patients Open
Active surveillance in our neonatal intensive care unit identified Staphylococcus aureus cultures from two infants with heterogeneity in methicillin resistance between isolated subclones lacking mecA and mecC . Whole-genome analysis of 4 m…
View article: Before the Surge: Molecular Evidence of SARS-CoV-2 in New York City Prior to the First Report
Before the Surge: Molecular Evidence of SARS-CoV-2 in New York City Prior to the First Report Open
New York City (NYC) emerged as a coronavirus disease 2019 (COVID-19) epicenter in March 2020, but there is limited information regarding potentially unrecognized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections befor…
View article: Lemierre’s syndrome associated with hypervirulent Klebsiella pneumoniae: A case report and genomic characterization of the isolate
Lemierre’s syndrome associated with hypervirulent Klebsiella pneumoniae: A case report and genomic characterization of the isolate Open
We describe a case of Lemierre's syndrome (LS) caused by a hypervirulent strain of Klebsiella pneumoniae in a 63-year-old female with hypertension, hyperlipidemia, and diabetes mellitus, who presented with right neck pain and fevers…
View article: Shedding of Viable SARS-CoV-2 after Immunosuppressive Therapy for Cancer
Shedding of Viable SARS-CoV-2 after Immunosuppressive Therapy for Cancer Open
Shedding of SARS-CoV-2 after Immunosuppression The prolonged contagious period after viral infection in immunocompromised patients may affect how long precautions will be necessary to reduce furthe...
View article: PathoSPOT genomic epidemiology reveals under-the-radar nosocomial outbreaks
PathoSPOT genomic epidemiology reveals under-the-radar nosocomial outbreaks Open
View article: SARS-CoV-2 Transmission among Marine Recruits during Quarantine
SARS-CoV-2 Transmission among Marine Recruits during Quarantine Open
Among Marine Corps recruits, approximately 2% who had previously had negative results for SARS-CoV-2 at the beginning of supervised quarantine, and less than 2% of recruits with unknown previous status, tested positive by day 14. Most recr…
View article: SARS-CoV-2 spread across the Colombian-Venezuelan border
SARS-CoV-2 spread across the Colombian-Venezuelan border Open
View article: <i>Staphylococcus aureus</i> Bacteremia in Patients Infected With COVID-19: A Case Series
<i>Staphylococcus aureus</i> Bacteremia in Patients Infected With COVID-19: A Case Series Open
Background Previous viral pandemics have shown that secondary bacterial infections result in higher morbidity and mortality, with Staphylococcus aureus being the primary causative pathogen. The impact of secondary S. aureus bacteremia on m…
View article: 261. A Single-Center Case Series of Methicillin-Resistant <i>S. aureus</i> Bacteremia with Elevated Minimal Inhibitory Concentrations to Vancomycin
261. A Single-Center Case Series of Methicillin-Resistant <i>S. aureus</i> Bacteremia with Elevated Minimal Inhibitory Concentrations to Vancomycin Open
Background Methicillin-resistant Staphylococcus aureus (MRSA) is a serious nosocomial pathogen, and is listed as a “High Priority Pathogen” by the WHO due to concerns of antimicrobial resistance and lack of novel therapeutics. Even in vanc…
View article: SARS-CoV-2 spread across the Colombian-Venezuelan border
SARS-CoV-2 spread across the Colombian-Venezuelan border Open
Introduction Venezuela and Colombia both adopted measures of containment early in response to the COVID-19 pandemic. However, Venezuela’s ongoing humanitarian crisis has decimated its health care system, and forced millions of Venezuelans …
View article: Introductions and early spread of SARS-CoV-2 in the New York City area
Introductions and early spread of SARS-CoV-2 in the New York City area Open
Blighted Gotham Deaths caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in New York City (NYC) during the spring of 2020 have vastly exceeded those reported in China and many other countries. What were the early event…
View article: PathoSPOT genomic epidemiology reveals under-the-radar nosocomial outbreaks
PathoSPOT genomic epidemiology reveals under-the-radar nosocomial outbreaks Open
Whole genome sequencing (WGS) is increasingly used to map the spread of bacterial and viral pathogens in nosocomial settings. A limiting factor for more widespread adoption of WGS for hospital infection prevention practices is the availabi…
View article: Introductions and early spread of SARS-CoV-2 in the New York City area
Introductions and early spread of SARS-CoV-2 in the New York City area Open
New York City (NYC) has emerged as one of the epicenters of the current SARS-CoV2 pandemic. To identify the early events underlying the rapid spread of the virus in the NYC metropolitan area, we sequenced the virus causing COVID19 in patie…
View article: Additional file 1 of PathoSPOT genomic epidemiology reveals under-the-radar nosocomial outbreaks
Additional file 1 of PathoSPOT genomic epidemiology reveals under-the-radar nosocomial outbreaks Open
Additional file 1. This file contains Supplementary Table S1, which lists the bacterial genome assembly details.
View article: 552. Within-Host Evaluation of Colonization During Active Methicillin-Resistant S. aureus Bacteremia
552. Within-Host Evaluation of Colonization During Active Methicillin-Resistant S. aureus Bacteremia Open
Background Staphylococcus aureus is a common commensal pathogen and a frequent cause of bacteremia, with nasal and blood isolates from single patients matching >80% of the time. Based on our prior work on paired single-patient isolates,1 o…
View article: 2129. When Is Methicillin-resistant Staphylococcus aureus not Methicillin-resistant Staphylococcus aureus?
2129. When Is Methicillin-resistant Staphylococcus aureus not Methicillin-resistant Staphylococcus aureus? Open
Background As part of active surveillance in our NICU for methicillin-resistant Staphylococcus aureus (MRSA), two isolates representing modified S. aureus (MODSA), which are Methicillin resistant but lacking mecA or C were identified. Our …
View article: Applying Computational Solutions for solving problems in Mammalian Gene Family Evolution and Single Cell Gene Expression Analysis
Applying Computational Solutions for solving problems in Mammalian Gene Family Evolution and Single Cell Gene Expression Analysis Open
Archival abstract submitted