Ajay S Krishnan
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View article: Case Studies From India: Management of Diabetes Using Continuous Glucose Monitoring
Case Studies From India: Management of Diabetes Using Continuous Glucose Monitoring Open
Continuous glucose monitoring (CGM) has significantly advanced diabetes management by enabling real-time glucose tracking. However, many patients with diabetes still fail to achieve optimal glycemic control. This case series reviews the ro…
View article: A comprehensive analysis of epithelioid hemangioendothelioma from a tertiary cancer center in India
A comprehensive analysis of epithelioid hemangioendothelioma from a tertiary cancer center in India Open
Introduction Epithelioid hemangioendothelioma (EHE), a rare vascular malignancy is categorized under malignant vascular neoplasm by the International Society for the Study of Vascular Anomalies (ISSVA) classification and the World Health O…
View article: Exploring Clinicopathological and Immunomorphologic Profile of Primary Head Neck Synovial Sarcoma Cases from a Tertiary Care Cancer Centre in India
Exploring Clinicopathological and Immunomorphologic Profile of Primary Head Neck Synovial Sarcoma Cases from a Tertiary Care Cancer Centre in India Open
Synovial sarcoma (SS) is a malignant mesenchymal neoplasm with variable epithelial differentiation, with a propensity to occur in young adults. The pathognomonic t(X;18) chromosomal translocation and subsequent development of the SS18:SSX …
View article: Positron emission tomography directed re-irradiation using volumetric modulated arc technique in recurrent head and neck squamous cell carcinoma
Positron emission tomography directed re-irradiation using volumetric modulated arc technique in recurrent head and neck squamous cell carcinoma Open
Advancements in surgical and radiotherapy techniques have enhanced locoregional control (LRC) in head and neck squamous cell carcinoma (HNSCC), yet 30-40% of patients still experience recurrence within 2-3 years. Salvage surgery can result…
View article: Comparison of Quality of Life in Postoperative High-Grade Glioma Patients Treated Using EORTC and RTOG Target Delineation Techniques for Postoperative Radiotherapy
Comparison of Quality of Life in Postoperative High-Grade Glioma Patients Treated Using EORTC and RTOG Target Delineation Techniques for Postoperative Radiotherapy Open
High-grade gliomas (HGGs) have dismal prognosis even with multimodality treatment entailing surgery, radiotherapy, and chemotherapy. Hence, assessment of improvement in quality of life (QOL) for evaluating treatment is critical. Target del…
View article: Evaluation of spatial correlation of external beam radiotherapy and interstitial brachytherapy with deformable image registration (DIR)-based dose summation in early head and neck squamous cell carcinoma
Evaluation of spatial correlation of external beam radiotherapy and interstitial brachytherapy with deformable image registration (DIR)-based dose summation in early head and neck squamous cell carcinoma Open
DIR software-based dose summation provides accurate dose delivery to target and OARs. If performed prospectively, it can potentially enable optimization of limiting the doses to critical OARs, thus, reducing post-RT morbidity.
View article: Effectiveness of Telemedicine Interventions in Chronic Obstructive Pulmonary Disease (COPD) Management: A Randomized Controlled Trial Comparing Yoga Therapy and Pulmonary Rehabilitation Over Three Months
Effectiveness of Telemedicine Interventions in Chronic Obstructive Pulmonary Disease (COPD) Management: A Randomized Controlled Trial Comparing Yoga Therapy and Pulmonary Rehabilitation Over Three Months Open
Background Pulmonary rehabilitation (PR) is an integral part of non-pharmacological therapy in chronic obstructive pulmonary disease (COPD). Yoga therapy (YT) has been shown to be beneficial in COPD, but the lack of large well-designed tri…
View article: MV CBCT based assessment of setup uncertainties and planning target volume margin in head and neck cancer
MV CBCT based assessment of setup uncertainties and planning target volume margin in head and neck cancer Open
An isometric PTV margin of 5 mm may be considered safe if daily imaging is not being done. In case daily online pretreatment imaging is being utilized, further reduction of PTV margin is possible.
View article: A Prospective Randomized Study of Sequential Boost vs Simultaneous Integrated Boost Intensity-Modulated Radiation Therapy with Concurrent Chemotherapy in Locally Advanced Head and Neck Cancer
A Prospective Randomized Study of Sequential Boost vs Simultaneous Integrated Boost Intensity-Modulated Radiation Therapy with Concurrent Chemotherapy in Locally Advanced Head and Neck Cancer Open
Background: In modern radiotherapy era of Intensity Modulated Radiotherapy (IMRT) and Volumetric Modulated Arc Therapy (VMAT), boost of locally advanced head and neck cancer (LAHNC) can be delivered as a sequential or simultaneous integrat…
View article: Referee report. For: Opioid use disorder and role of yoga as an adjunct in management (OUDARYAM): Study protocol for a randomized controlled trial [version 1; peer review: 1 approved]
Referee report. For: Opioid use disorder and role of yoga as an adjunct in management (OUDARYAM): Study protocol for a randomized controlled trial [version 1; peer review: 1 approved] Open
View article: Treatment Outcomes and Survival in Hypercalcemia of Malignancy: A Grave Metabolic Emergency
Treatment Outcomes and Survival in Hypercalcemia of Malignancy: A Grave Metabolic Emergency Open
View article: Clinicopathological characteristics and management of extramedullary hematopoiesis: A review
Clinicopathological characteristics and management of extramedullary hematopoiesis: A review Open
Extramedullary hematopoiesis (EMH) is a rare entity most often associated with primary myelofibrosis, chronic myeloproliferative neoplasms, chronic hemolytic states, such as thalassemia, sickle cell anemia and certain solid tumors. Various…
View article: Exercise Capacity in Patients With Chronic Obstructive Pulmonary Disease Treated With Tele-Yoga Versus Tele-Pulmonary Rehabilitation: A Pilot Validation Study
Exercise Capacity in Patients With Chronic Obstructive Pulmonary Disease Treated With Tele-Yoga Versus Tele-Pulmonary Rehabilitation: A Pilot Validation Study Open
Background In chronic obstructive pulmonary disease (COPD), pulmonary rehabilitation (PR) is an integral component of the non-pharmacological management of COPD. Yoga has proven to be beneficial in COPD, although well-designed comparative …
View article: Metachronous Osseous Metastases From Gliobliostoma Mutiforme: An Unusual Presentation
Metachronous Osseous Metastases From Gliobliostoma Mutiforme: An Unusual Presentation Open
View article: A Prospective Randomized Study of Intensity-Modulated Radiation Therapy Versus Three-Dimensional Conformal Radiation Therapy With Concurrent Chemotherapy in Locally Advanced Carcinoma Cervix
A Prospective Randomized Study of Intensity-Modulated Radiation Therapy Versus Three-Dimensional Conformal Radiation Therapy With Concurrent Chemotherapy in Locally Advanced Carcinoma Cervix Open
IMRT is associated with decreased acute hematological toxicity compared to 3DCRT with similar local control. Long-term follow-up is needed to assess any difference in long-term toxicity and survival between the two arms.
View article: Synchronous dual malignancy: a rare case report of carcinoma breast with carcinoma gall bladder
Synchronous dual malignancy: a rare case report of carcinoma breast with carcinoma gall bladder Open
Incidence of multiple primary cancers is reported to be between 0.18% to 17.2% in various studies. Occurrence of breast and gall bladder malignancy as synchronous malignancy is very rare. We are reporting one of such rare case. Our patient…
View article: Clinical profile of pediatric malignancies in a new tertiary cancer care unit in Uttarakhand, India
Clinical profile of pediatric malignancies in a new tertiary cancer care unit in Uttarakhand, India Open