Ajeeth Iyer
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View article: High-Throughput Targeted Drug Screening for NF1-associated High-Grade Gliomas with ATRX Deficiency
High-Throughput Targeted Drug Screening for NF1-associated High-Grade Gliomas with ATRX Deficiency Open
Neurofibromatosis type 1 (NF1)-associated high-grade gliomas (HGGs) harboring ATRX mutations exhibit an aggressive clinical phenotype, driven by heightened genomic instability and metabolic reprogramming. Existing therapies, including chem…