Ajith K. Siriwardena
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View article: Effect of unplanned conversion to open surgery on resection margins and postoperative complications in minimally-invasive resection of colorectal liver metastases: A systematic review and meta-analysis with meta-regression
Effect of unplanned conversion to open surgery on resection margins and postoperative complications in minimally-invasive resection of colorectal liver metastases: A systematic review and meta-analysis with meta-regression Open
Unplanned conversion to open may carry prognostic and oncological implications for minimally-invasive resection of CRLM. Although conversion due to bleeding and iatrogenic injury is routinely considered, conversion prompted by technical di…
View article: The E-AHPBA – ESSO – Innsbruck consensus recommendations on peri- and postoperative management following liver resection
The E-AHPBA – ESSO – Innsbruck consensus recommendations on peri- and postoperative management following liver resection Open
Optimising perioperative care after hepatectomy remains challenging. Standardising key practices and addressing evidence gaps through collaborative research are vital to improve outcomes.
View article: Correction: Analysis of Short-Term Outcomes in Pancreatic Surgery with Vascular Resection from a Prospective Multicenter Global Study
Correction: Analysis of Short-Term Outcomes in Pancreatic Surgery with Vascular Resection from a Prospective Multicenter Global Study Open
View article: Analysis of Short-Term Outcomes in Pancreatic Surgery with Vascular Resection from a Prospective Multicenter Global Study
Analysis of Short-Term Outcomes in Pancreatic Surgery with Vascular Resection from a Prospective Multicenter Global Study Open
View article: Development and validation of a diagnostic prediction model for pancreatic ductal adenocarcinoma: VAPOR 1, protocol for a prospective multicentre case–control study
Development and validation of a diagnostic prediction model for pancreatic ductal adenocarcinoma: VAPOR 1, protocol for a prospective multicentre case–control study Open
Introduction Pancreatic ductal adenocarcinoma (PDAC) continues to have extremely poor patient outcomes, unlike other cancer types which have seen significant improvements in their treatments and survival. A major contributing factor is tha…
View article: The Brescia International Multidisciplinary Consensus Guidelines on the Optimal Pathology Assessment and Multidisciplinary Pathways of Non‐Pancreatic Neoplasms in and Around the Ampulla of Vater (PERIPAN)
The Brescia International Multidisciplinary Consensus Guidelines on the Optimal Pathology Assessment and Multidisciplinary Pathways of Non‐Pancreatic Neoplasms in and Around the Ampulla of Vater (PERIPAN) Open
Importance The lack of multidisciplinary workflow guidelines and clear definitions and classifications for neoplasms in and around the ampulla of Vater results in inconsistencies affecting patient care and research. Objective The PERIPAN i…
View article: Comparison of perioperative outcomes of open (CUSA) versus laparoscopic (LOTUS) major hepatectomy – revisited. First evaluation of efficacy and safety of AEON™ stapler
Comparison of perioperative outcomes of open (CUSA) versus laparoscopic (LOTUS) major hepatectomy – revisited. First evaluation of efficacy and safety of AEON™ stapler Open
Introduction In 2019, preliminary data matching 20 laparoscopic (using LOTUS) with 20 open (using CUSA) cases demonstrated the feasibility and improved outcomes of laparoscopic major liver resections using the LOTUS™ liver blade. This upda…
View article: Spatial gene regulatory networks driving cell state transitions during human liver disease
Spatial gene regulatory networks driving cell state transitions during human liver disease Open
View article: Irreversible electroporation as an intraoperative adjunctive treatment for locally advanced pancreatic cancer after neoadjuvant therapy: An initial clinical experience
Irreversible electroporation as an intraoperative adjunctive treatment for locally advanced pancreatic cancer after neoadjuvant therapy: An initial clinical experience Open
This report shows that in patients with LAPC undergoing exploratory surgery following NAT, IRE seems technically feasible for margin accentuation or as a "back-up therapy". More data are needed to determine procedure-related morbidity, mor…
View article: Robotic distal pancreatectomy: Initial experience with the Versius robotic surgical system. Stage 2a IDEAL prospective case series
Robotic distal pancreatectomy: Initial experience with the Versius robotic surgical system. Stage 2a IDEAL prospective case series Open
Background: Distal pancreatectomy (DP) is a well-established minimally invasive procedure. However, feasibility and technical details when using Versius robotic surgical system are still unexplored. Method: This is a prospective stage 2a d…
View article: Management of Colorectal Cancer with Synchronous Liver Metastases: A systematic review of national and International Clinical Guidelines (CoSMIC-G)
Management of Colorectal Cancer with Synchronous Liver Metastases: A systematic review of national and International Clinical Guidelines (CoSMIC-G) Open
This study demonstrates important variations between international clinical guidelines on diagnostic workup and management of synchronous liver metastases in colorectal cancer. [167 words].
View article: International Delphi consensus on the management of percutaneous choleystostomy in acute cholecystitis (E-AHPBA, ANS, WSES societies)
International Delphi consensus on the management of percutaneous choleystostomy in acute cholecystitis (E-AHPBA, ANS, WSES societies) Open
Background There has been a progressive increase in the use of percutaneous cholecystostomy (PC) in acute cholecystitis (AC) over the last decades due to population aging, and the support of guidelines (Tokyo Guidelines (TG), World Society…
View article: Estimation of intraoperative blood loss in hepatopancreatobiliary surgery: a Delphi consensus process of the European–African Hepato-Pancreato-Biliary Association (E-AHPBA)
Estimation of intraoperative blood loss in hepatopancreatobiliary surgery: a Delphi consensus process of the European–African Hepato-Pancreato-Biliary Association (E-AHPBA) Open
View article: Evidence-based management of the patient with synchronous colorectal cancer and liver metastases
Evidence-based management of the patient with synchronous colorectal cancer and liver metastases Open
View article: Benefits and barriers to accreditation of HPB center and fellowship programs in Europe: a strength-weakness-opportunity-and-threats (SWOT) analysis by an E-AHPBA-ESSO-UEMS ad hoc working committee
Benefits and barriers to accreditation of HPB center and fellowship programs in Europe: a strength-weakness-opportunity-and-threats (SWOT) analysis by an E-AHPBA-ESSO-UEMS ad hoc working committee Open
This study identified both helpful and harmful effects to an accreditation process of HPB centers or HPB fellowship training across the E-AHPBA membership region. Formal accreditation of centers is not within the scope, nor jurisdiction no…
View article: Toward a new paradigm of care: a surgical leaders’ Delphi consensus on the organizational factors of the new pancreas units (E-AHPBA PUECOF study)
Toward a new paradigm of care: a surgical leaders’ Delphi consensus on the organizational factors of the new pancreas units (E-AHPBA PUECOF study) Open
Pancreas units represent new organizational models of care that are now at the center of the European debate. The PUECOF study, endorsed by the European–African Hepato-Pancreato-Biliary Association (E-AHPBA), aims to reach an expert consen…
View article: Current Practice in the Treatment of Colorectal Liver Metastases by Irreversible Electroporation: A Focus-Group International Questionnaire Survey (LIVERMET-IRE-Q).
Current Practice in the Treatment of Colorectal Liver Metastases by Irreversible Electroporation: A Focus-Group International Questionnaire Survey (LIVERMET-IRE-Q). Open
Background: Irreversible electroporation (IRE) is a form of non-thermal ablation that delivers pulses of high voltage electrical current between electrodes. The role of IRE in the treatment of colorectal hepatic metastases is unestablished…
View article: Gaza War: Too many citizens being killed
Gaza War: Too many citizens being killed Open
View article: Standardizing definitions and terminology of left-sided pancreatic resections through an international Delphi consensus
Standardizing definitions and terminology of left-sided pancreatic resections through an international Delphi consensus Open
no abstract available
View article: Opioid analgesia and severity of acute pancreatitis: An international multicentre cohort study on pain management in acute pancreatitis
Opioid analgesia and severity of acute pancreatitis: An international multicentre cohort study on pain management in acute pancreatitis Open
Background The effect of analgesic modalities on short‐term outcomes in acute pancreatitis remains unknown. However, preclinical models have raised safety concerns regarding opioid use in patients with acute pancreatitis. Objective This st…
View article: REDISCOVER International Guidelines on the Perioperative Care of Surgical Patients With Borderline-resectable and Locally Advanced Pancreatic Cancer
REDISCOVER International Guidelines on the Perioperative Care of Surgical Patients With Borderline-resectable and Locally Advanced Pancreatic Cancer Open
Objective: The REDISCOVER consensus conference aimed at developing and validating guidelines on the perioperative care of patients with borderline-resectable (BR-) and locally advanced (LA) pancreatic ductal adenocarcinoma (PDAC). Backgrou…
View article: European fellowship training opportunities for hepato-pancreato-biliary surgery: an international survey of fellows and program directors
European fellowship training opportunities for hepato-pancreato-biliary surgery: an international survey of fellows and program directors Open
There is substantial heterogeneity between HPB fellowship programs in Europe. A wider standardization of clinical curriculum, including minimally invasive surgery, is desirable.
View article: E-AHPBA mentorship program
E-AHPBA mentorship program Open
View article: International multidisciplinary consensus guidelines on the optimal pathology assessment and multidisciplinary pathways of non-pancreatic neoplasms in and around the ampulla of vater
International multidisciplinary consensus guidelines on the optimal pathology assessment and multidisciplinary pathways of non-pancreatic neoplasms in and around the ampulla of vater Open
View article: Pancreatic surgery outcomes: multicentre prospective snapshot study in 67 countries
Pancreatic surgery outcomes: multicentre prospective snapshot study in 67 countries Open
Background Pancreatic surgery remains associated with high morbidity rates. Although postoperative mortality appears to have improved with specialization, the outcomes reported in the literature reflect the activity of highly specialized c…
View article: “Locally Treatable” to Replace “Resectable”: Highlights from the European Multi-societal Consensus on Synchronous Colorectal Cancer with Liver Metastases
“Locally Treatable” to Replace “Resectable”: Highlights from the European Multi-societal Consensus on Synchronous Colorectal Cancer with Liver Metastases Open
View article: International survey on opinions and use of robot-assisted and laparoscopic minimally invasive pancreatic surgery: 5-year follow up
International survey on opinions and use of robot-assisted and laparoscopic minimally invasive pancreatic surgery: 5-year follow up Open
View article: Development and validation of a novel risk score to predict overall survival following surgical clearance of bilobar colorectal liver metastases
Development and validation of a novel risk score to predict overall survival following surgical clearance of bilobar colorectal liver metastases Open
Background Bilobar liver metastases from colorectal cancer pose a challenge for obtaining a satisfactory oncological outcome with an adequate future liver remnant. This study aimed to assess the clinical and pathological determinants of ov…
View article: FTP7.6 Management of Colorectal Cancer with Synchronous Liver Metastases: A systematic review of national and international clinical guidelines (CoSMIC-G)
FTP7.6 Management of Colorectal Cancer with Synchronous Liver Metastases: A systematic review of national and international clinical guidelines (CoSMIC-G) Open
Introduction The contemporary management of patients with colorectal cancer and synchronous liver metastases is complex. Variation in interpretation of the limited body of evidence may introduce inequality in practice. This study appraises…
View article: E-AHPBA–ESSO–ESSR Innsbruck consensus guidelines for preoperative liver function assessment before hepatectomy
E-AHPBA–ESSO–ESSR Innsbruck consensus guidelines for preoperative liver function assessment before hepatectomy Open
Background Posthepatectomy liver failure (PHLF) contributes significantly to morbidity and mortality after liver surgery. Standardized assessment of preoperative liver function is crucial to identify patients at risk. These European consen…