Ali A. Asadi‐Pooya
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View article: Availability and affordability of cannabinoids for epilepsy treatment across different geographic settings—A survey from the <scp>ILAE</scp> Plant‐Based Therapy Task Force
Availability and affordability of cannabinoids for epilepsy treatment across different geographic settings—A survey from the <span>ILAE</span> Plant‐Based Therapy Task Force Open
Pharmacoresistant seizures remain a major challenge for the global epilepsy community. Hence, approval of highly purified pharmaceutical grade cannabidiol (CBD) for Dravet syndrome (DS), Lennox–Gastaut syndrome (LGS), and refractory seizur…
View article: Attitude of people with epilepsy in Serbia toward surgical treatment of epilepsy
Attitude of people with epilepsy in Serbia toward surgical treatment of epilepsy Open
Objective Approximately, one‐third of patients with epilepsy (PWE) have drug‐resistant epilepsy (DRE). This condition significantly impacts quality of life, leads to various negative socioeconomic consequences, and increases the risk of su…
View article: Altered along‐the‐perivascular space index in functional (psychogenic non‐epileptic) seizures: A diffusion tensor imaging study of glymphatic system function
Altered along‐the‐perivascular space index in functional (psychogenic non‐epileptic) seizures: A diffusion tensor imaging study of glymphatic system function Open
Objective The glymphatic system is a critical brain waste‐clearance mechanism that facilitates the removal of metabolic byproducts and maintains neural homeostasis. Its dysfunction has been implicated in various neurological disorders; how…
View article: Continuing medical education in epileptology: The Level 1‐2‐3 experience of the <scp>ILAE</scp> academy
Continuing medical education in epileptology: The Level 1‐2‐3 experience of the <span>ILAE</span> academy Open
The International League Against Epilepsy (ILAE) Academy is the world's eminent e‐learning campus for epileptology. Its modular teaching content was developed to cover all competencies and learning objectives specified in the ILAE's curric…
View article: Epilepsy Diagnosis When the Routine Ancillary Tests Are Normal
Epilepsy Diagnosis When the Routine Ancillary Tests Are Normal Open
Background/Objectives: In a patient suspected of having epilepsy, routine EEG primarily contributes to the recording of interictal epileptiform discharges (IEDs). Similarly, magnetic resonance imaging (MRI) has become the gold standard ima…
View article: Epilepsy Diagnosis When the Routine Ancillary Tests Are Normal
Epilepsy Diagnosis When the Routine Ancillary Tests Are Normal Open
Epilepsy is a clinical diagnosis. In a patient suspected of epilepsy, the main contribution of routine EEG is to record interictal epileptiform discharges (IEDs) which include spikes, sharp waves, spike-and-wave discharges, sharp-and-wave …
View article: Sex Differences in Epilepsies: A Narrative Review
Sex Differences in Epilepsies: A Narrative Review Open
Epilepsy affects people of all ages and sexes. The aim of the current narrative review was to summarize the sex differences in patients with epilepsy. In January 2024, we systematically searched PubMed for relevant articles. The following …
View article: Erratum to: Abstractband—16th International Epilepsy Course and Colloquium
Erratum to: Abstractband—16th International Epilepsy Course and Colloquium Open
View article: Generalized spike–waves in idiopathic generalized epilepsies: Does their frequency matter?
Generalized spike–waves in idiopathic generalized epilepsies: Does their frequency matter? Open
Objectives We hypothesized that the frequency (in Hertz) of generalized spike–waves (GSWs) in patients with idiopathic generalized epilepsy (IGE) has associations with the syndromic diagnosis as well as with the prognosis of patients (thei…
View article: The burden of neurological conditions in north Africa and the Middle East, 1990–2019: a systematic analysis of the Global Burden of Disease Study 2019
The burden of neurological conditions in north Africa and the Middle East, 1990–2019: a systematic analysis of the Global Burden of Disease Study 2019 Open
For the Persian, Arabic and Turkish translations of the abstract see Supplementary Materials section.
View article: Core outcome measurement set for research and clinical practice in post-COVID-19 condition (long COVID) in children and young people: an international Delphi consensus study “PC-COS Children”
Core outcome measurement set for research and clinical practice in post-COVID-19 condition (long COVID) in children and young people: an international Delphi consensus study “PC-COS Children” Open
The coronavirus disease 2019 (COVID-19) pandemic substantially impacted different age groups, with children and young people not exempted. Many have experienced enduring health consequences. Presently, there is no consensus on the health o…
View article: Interactions between antiseizure medications and foods and drinks: A systematic review
Interactions between antiseizure medications and foods and drinks: A systematic review Open
Antiseizure medications (ASMs) constitute the principal of treatment for patients with epilepsy, where long‐term treatment is usually necessary. The purpose of this systematic review is to provide practical and useful information regarding…
View article: Complementary and Alternative Medicine for People with Epilepsy: Opinions of Physicians in Oman
Complementary and Alternative Medicine for People with Epilepsy: Opinions of Physicians in Oman Open
Objectives:Several studies have explored the opinions of healthcare workers on the use of complementary and alternative medicine (CAM) in epilepsy treatment. We sought to survey the views of non-neurologist and non-psychiatrist physicians …
View article: How does COVID-19 vaccination affect long-COVID symptoms?
How does COVID-19 vaccination affect long-COVID symptoms? Open
Objective The current study aimed to identify the association between COVID-19 vaccination and prolonged post-COVID symptoms (long-COVID) in adults who reported suffering from this condition. Methods This was a retrospective follow-up stud…
View article: Response to the Letter Concerning the Publication: Neuroimaging in Functional Neurological Disorder: State of the Field and Research Agenda. Perez DL et al. Neuroimage Clin. 2021;30:102623
Response to the Letter Concerning the Publication: Neuroimaging in Functional Neurological Disorder: State of the Field and Research Agenda. Perez DL et al. Neuroimage Clin. 2021;30:102623 Open
View article: The Longevity of Long COVID and the Diagnosis-Related Challenges
The Longevity of Long COVID and the Diagnosis-Related Challenges Open
Background: Long COVID syndrome (LCS) is characterized by chronic symptoms of fatigue, cough, etc. after contracting COVID-19. This study aimed to identify the longevity of the symptoms of adults who reported suffering from LCS in our prev…
View article: Response: Letter to <scp>FKBP5</scp> blockade may provide a new horizon for the treatment of stress‐associated disorders: An in silico study
Response: Letter to <span>FKBP5</span> blockade may provide a new horizon for the treatment of stress‐associated disorders: An in silico study Open
View article: Polymorphism of glucocorticoid receptor gene (<i>rs41423247</i>) in functional seizures (psychogenic nonepileptic seizures/attacks)
Polymorphism of glucocorticoid receptor gene (<i>rs41423247</i>) in functional seizures (psychogenic nonepileptic seizures/attacks) Open
Objective We investigated the association between the glucocorticoid receptor (GR) gene, also known as the nuclear receptor subfamily 3, group C, member 1 (NR3C1), rs41423247 polymorphism, and functional seizures (psychogenic nonepileptic …
View article: Epilepsy classification using artificial intelligence: A web‐based application
Epilepsy classification using artificial intelligence: A web‐based application Open
Objective The purpose of the current endeavor was to evaluate the feasibility of using easily accessible and applicable clinical information (based on history taking and physical examination) in order to make a reliable differentiation bet…
View article: Cannabidiol for functional seizures (psychogenic nonepileptic seizures/attacks) and other stress‐associated disorders
Cannabidiol for functional seizures (psychogenic nonepileptic seizures/attacks) and other stress‐associated disorders Open
Recently, we published a paper that suggested that FKBP5 single-nucleotide polymorphisms may play a role in functional seizures (psychogenic nonepileptic seizures/attacks).1 We also published another paper entitled “FKBP5 blockade may prov…
View article: Genetics of Functional Seizures; A Scoping Systematic Review
Genetics of Functional Seizures; A Scoping Systematic Review Open
Background: Evidence on the genetics of functional seizures is scarce, and the purpose of the current scoping systematic review is to examine the existing evidence and propose how to advance the field. Methods: Web of science and MEDLINE w…
View article: Nano‐delivery systems as a promising therapeutic potential for epilepsy: Current status and future perspectives
Nano‐delivery systems as a promising therapeutic potential for epilepsy: Current status and future perspectives Open
Epilepsy is a common chronic neurological disorder caused by aberrant neuronal electrical activity. Antiseizure medications (ASMs) are the first line of treatment for people with epilepsy (PWE). However, their effectiveness may be limited …
View article: <i>FKBP5</i> blockade may provide a new horizon for the treatment of stress‐associated disorders: An in‐silico study
<i>FKBP5</i> blockade may provide a new horizon for the treatment of stress‐associated disorders: An in‐silico study Open
Objective We searched for, from the FDA (Food and Drug Administration‐USA)‐approved drugs, inhibitors of FKBP5 with tolerable adverse effect profiles (eg, mild headache, sedation, etc.) and with the ability to cross the blood brain barrier…
View article: Use of Integrative, Complementary, and Alternative Medicine in Children with Epilepsy: A Global Scoping Review
Use of Integrative, Complementary, and Alternative Medicine in Children with Epilepsy: A Global Scoping Review Open
(1) Background: Epilepsy is one of the most common chronic neurological disorders in childhood. Complementary and alternative medicine (CAM) use is highly prevalent in patients with epilepsy. Despite CAM’s widespread and increasing popular…
View article: The genetic link between systemic autoimmune disorders and temporal lobe epilepsy: A bioinformatics study
The genetic link between systemic autoimmune disorders and temporal lobe epilepsy: A bioinformatics study Open
Objective We aimed to explore the underlying pathomechanisms of the comorbidity between three common systemic autoimmune disorders (SADs) [i.e., insulin‐dependent diabetes mellitus (IDDM), systemic lupus erythematosus (SLE), and rheumatoid…
View article: Potential role of <i>FKBP5</i> single‐nucleotide polymorphisms in functional seizures
Potential role of <i>FKBP5</i> single‐nucleotide polymorphisms in functional seizures Open
Objective We investigated the associations between FKBP5 single‐nucleotide polymorphisms (SNPs) and functional seizures (FS). Methods Seventy patients with FS, 140 with major depressive disorder (MDD), and 140 healthy controls were studied…
View article: Are brain MRI abnormalities associated with the semiology of functional seizures?
Are brain MRI abnormalities associated with the semiology of functional seizures? Open
Purpose To investigate whether radiologically apparent brain magnetic resonance imaging (MRI) abnormalities are associated with the functional seizure (FS) semiology. Methods All patients with a diagnosis of FS at the epilepsy centers at S…
View article: Antiseizure Effects of <i>Peganum harmala</i> L. and <i>Lavandula angustifolia</i>
Antiseizure Effects of <i>Peganum harmala</i> L. and <i>Lavandula angustifolia</i> Open
Peganum harmala L. and Lavandula angustifolia are two traditional herbs with probable antiseizure effects. This study evaluated the effects of these two herbal extracts on pentylenetetrazol‐ (PTZ‐) induced seizures in mice. We prepared hyd…
View article: Association of Human Leukocyte Antigen Alleles with Carbamazepine- or Lamotrigine-Induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in an Iranian Population: A Case-control Study.
Association of Human Leukocyte Antigen Alleles with Carbamazepine- or Lamotrigine-Induced Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis in an Iranian Population: A Case-control Study. Open
Overall, no significant association was found between CBZ- or LTG-induced SJS/TEN and HLA alleles. Further large-scale studies are required to substantiate our findings.
View article: Long-Lasting COVID-Associated Brain Fog: A Follow-Up Study
Long-Lasting COVID-Associated Brain Fog: A Follow-Up Study Open
Introduction: We investigated the longevity of COVID-associated brain fog in patients who have survived the COVID-19. Methods: This was a follow-up study of 2,696 adult patients with COVID-19 from our previous study. We selected every othe…