Explanipedia

Interoception and dissociation in migraine: a case–control study of chronic and episodic subtypes Open

Akihiro Koreki, Varun Bhatia, Anne-Marie Logan, Usman Khan, Mitsumoto Onaya , et al. · 2025

Background Migraine is one of the most common neurological disorders. Despite advances in understanding of episodic migraine, little is understood about the mechanisms underlying the chronification of migraine. Recently, increasing attenti…

Impact of negative symptom reduction on employment and vocational activity outcomes following cognitive remediation therapy in schizophrenia: A 1‐year follow‐up study Open

Yasuhisa Nakamura, K Shimada, Reiko Miyamoto, Akihiro Koreki, Sachiko Anamizu , et al. · 2025

Aim Cognitive remediation therapy (CRT) improves cognitive function and enhances vocational outcomes in patients with schizophrenia. However, factors that facilitate employment or vocational activity transition following CRT remain unclear…

Reduced sensory attenuation is related to aberrant interoceptive influences on intentional binding in schizophrenia Open

Akihiro Koreki, Yuri Terasawa, Hiroki Oi, Takuya Mouri, Asako Takenaka , et al. · 2025

Aim Schizophrenia (SZ) is characterized by abnormalities in self‐representation, including an aberrant sense of agency (SoA). Experimentally observed abnormalities in force matching and intentional binding tasks suggest that the SoA in SZ …

Interrater reliability of the modified Tinkertoy test: A validation study in schizophrenia and control groups Open

Yasuhisa Nakamura, Reiko Miyamoto, Akihiro Koreki, Sachiko Anamizu, Masaru Mimura · 2025

Aim Divergent thinking and executive function are critical components of cognitive performance, necessitating reliable assessment tools to guide clinical decision‐making and research on cognitive deficits. This study aimed to evaluate the …

Scoring System for the Japanese Version of the ICECAP-A [Corrigendum] Open

Mitsuhiro Sado, Kengo Nagashima, Akihiro Koreki · 2025

[This corrects the article DOI: 10.2147/PRBM.S480328.].

Scoring System for the Japanese Version of the ICECAP-A Open

Mitsuhiro Sado, Kengo Nagashima, Akihiro Koreki · 2025

We developed a Japanese version of the ICECAP-A and demonstrated the feasibility of utilizing best-worst scaling in a non-European context. This approach allows for a more precise evaluation of quality of life (QoL) among individuals with …

DATA-DRIVEN DISEASE PROGRESSION PATTERNS OF BRAIN MORPHOLOGY IN SCHIZOPHRENIA: MORE PROGRESSED STAGES IN TREATMENT- RESISTANCE Open

Daichi Sone, Alexandra L. Young, Shunichiro Shinagawa, Sakiko Tsugawa, Yusuke Iwata , et al. · 2025

Background Given the heterogeneity, particularly in terms of treatment response, and possible disease progression in schizophrenia, identifying the neurobiological subtypes and progression patterns in each patient may lead to novel biomark…

Cost-effectiveness analysis of mindfulness-based cognitive therapy in patients with anxiety disorders in secondary mental health care settings alongside a randomized controlled trial Open

Mitsuhiro Sado, Akihiro Koreki, Akira Ninomiya, Chika Kurata, Sunre Park , et al. · 2024

Introduction Anxiety disorder is one of the most prevalent mental disorders. Mindfulness-based cognitive therapy (MBCT) is effective for treating anxiety disorders. However, no studies have investigated the cost-effectiveness of MBCT for a…

The association between salivary IL-6 and poor sleep quality assessed using Apple watches in stressed workers in Japan Open

Akihiro Koreki, Mitsuhiro Sado, Yasue Mitsukura, Hisateru Tachimori, Anna Kubota , et al. · 2024

Altered sense of agency in schizophrenia: the aberrant effect of cardiac interoceptive signals Open

Akihiro Koreki, Yuri Terasawa, Atsuo Nuruki, Hiroki Oi, Hugo Critchley , et al. · 2024

Background Schizophrenia (SZ) is characterized by abnormalities in self-representation, including a disturbed sense of agency (SoA). The continuous processing of sensory information concerning the internal state of the body (interoception)…

Learning about design for dementia: lessons from a Japan–UK network Open

Alison Bowes, Alison Dawson, Fiona Copland, Grant Gibson, Satoko Hotta , et al. · 2024

A multidisciplinary Japan–UK Network identified cross-cultural and cross-national lessons for research aimed at improving the design of homes for people living with dementia. Previous research has suggested that improved, multidimensionall…

Divergent thinking as a predictor of life skills in patients with schizophrenia: Evidence from the modified Tinkertoy Test Open

Yasuhisa Nakamura, Reiko Miyamoto, Akihiro Koreki, Sachiko Anamizu, Masaru Mimura · 2024

Aim Patients with schizophrenia often exhibit poor life skills, posing significant clinical challenges. Life skills comprise cognitive functions crucial for planning daily activities, including divergent thinking. However, the cognitive de…

Caution for psychiatrists: malignant hyperthermia risks with the anesthetic agent succinylcholine (Suxamethonium) during electroconvulsive therapy Open

Masaki Nakano, Michitaka Funayama, Taketo Takata, Riko Wakisaka, Genki Koyama , et al. · 2024

Background Malignant hyperthermia is a potentially lethal condition triggered by specific anesthetic drugs, especially a depolarizing muscle relaxant of succinylcholine (Suxamethonium). Despite the frequent use of succinylcholine with elec…

Caution for Psychiatrists: Malignant Hyperthermia Risks Following Electroconvulsive Therapy Open

Masaki Nakano, Taketo Takata, Riko Wakisaka, Genki Koyama, Akihiro Koreki , et al. · 2024

Background Malignant hyperthermia is a potentially lethal condition triggered by specific anesthetic drugs, especially a depolarizing muscle relaxant of suxamethonium. Despite the frequent use of suxamethonium with electroconvulsive therap…

Disease Progression Patterns of Brain Morphology in Schizophrenia: More Progressed Stages in Treatment Resistance Open

Daichi Sone, Alexandra L. Young, Shunichiro Shinagawa, Sakiko Tsugawa, Yusuke Iwata , et al. · 2023

Background and Hypothesis Given the heterogeneity and possible disease progression in schizophrenia, identifying the neurobiological subtypes and progression patterns in each patient may lead to novel biomarkers. Here, we adopted data-driv…

Spontaneous Bladder Rupture in a Catatonic Schizophrenia Patient Open

Megumi Miyakoshi, Takayuki Arai, Shin Kurose, Masataka Kaji, Jun Nakane , et al. · 2023

Catatonia is a psychiatric emergency in schizophrenia that often leads to excessive activation of the sympathetic nervous system. Urinary retention in catatonia is often underestimated but has potentially detrimental consequences. Herein, …

Caution to psychiatry ward: COVID‐19 pneumonia can manifest weeks or months after testing positive with a PCR test in individuals on preexisting immune‐suppressing medication Open

Masaki Nakano, Michitaka Funayama, Riko Wakisaka, Taketo Takata, Shun Kudo , et al. · 2023

Background Some patients are reported to develop depression immediately after COVID‐19 infection. Typically, hospitalization is arranged a week to 10 days after symptom onset to avoid outbreak in the psychiatric ward when infectivity is al…

Impaired cardiac modulation in patients with functional seizures: Results from a face intensity judgment task Open

Akihiro Koreki, Sarah N. Garfinkel, Hugo Critchley, Sarah Cope, Niruj Agrawal , et al. · 2023

Objective Although interoceptive abnormality in patients with functional seizure (FSs) has been demonstrated using explicit tasks, implicit measurements of interoception such as the effect of interoception on perceptual brain processes hav…

Psychotic self-renaming and its unique features: A case series Open

Akihiro Koreki, Shin Kurose, Masataka Kajia, Yuki Mashima, K. Iwamura , et al. · 2023

Changing one's own name is an unusual psychotic symptom in patients with schizophrenia. Particularly, when self-renaming is neither bizarre nor grandiose, such self-renaming may be sometimes underestimated as purposeful and other times nec…

Economic Evaluation Alongside a Randomized Controlled Trial of Mindfulness-Based Cognitive Therapy in Healthy Adults Open

Maki Nagaoka, Akihiro Koreki, Teppei Kosugi, Akira Ninomiya, Masaru Mimura , et al. · 2023

The results suggested that MBCT may be more cost-effective from a healthcare sector perspective and may be cost-beneficial from the employer's perspective.

Rightward lateralization of frontal cortex tau pathologies is associated with late‐onset psychosis: A PET study with 18F‐PM‐PBB3 Open

Shin Kurose, Keisuke Takahata, Sho Moriguchi, Kenji Tagai, Manabu Kubota , et al. · 2023

Background Several cohort studies have recently reported associations between late‐life psychosis and dementia, and postmortem studies have demonstrated that most individuals with late‐onset schizophrenia and delusional disorder had tau pa…

You are already dead: Case report of nihilistic delusions regarding others as one representation of Cotard's syndrome Open

Akihiro Koreki, Yuki Mashima, Akihiko Oda, Teruki Koizumi, Kazuhiro Koyanagi , et al. · 2023

Background While the symptom of “I am already dead” is a hallmark of Cotard's syndrome, also known as nihilistic delusions, the symptom of “you are already dead” has been neglected. Case presentation A woman aged in her 60s diagnosed with …

Disease progression patterns of brain morphology in schizophrenia: More progressed stages in treatment-resistance Open

Shinichiro Nakajima, Daichi Sone, Alexandra L. Young, Shunichiro Shinagawa, Sakiko Tsugawa , et al. · 2023

Given the heterogeneity and possible disease progression in schizophrenia, identifying the neurobiological subtypes and progression patterns in each patient may lead to the development of clinically useful biomarkers. In this cross-section…

Formulation of a Mapping Formula to Estimate Well-Being Utility from Clinical Subjective Well-Being Scales Open

Akihiro Koreki, Maki Nagaoka, Akira Ninomiya, Masaru Mimura, Mitsuhiro Sado · 2022

The mapping function of our formula was within the range of other reported mapping studies. We believe this formula is useful for cost effective analyses of several trials where utility data are lacking.

Functional cognitive disorder affects reaction time, subjective mental effort and global metacognition Open

Tiago Teodoro, Akihiro Koreki, Jiaying Chen, Jan Coebergh, Norman Poole , et al. · 2022

We previously hypothesized that functional cognitive disorder is characterized by heightened subjective mental effort, exhausted attentional reserve and metacognitive failure. To test this hypothesis, we administered a Stroop colour-word t…

The relationship between interoception and agency and its modulation by heartbeats: an exploratory study Open

Akihiro Koreki, Diana Goeta, Lucia Ricciardi, Talia Eilon, Jiaying Chen , et al. · 2022

Hypermobility in patients with functional seizures: Toward a pathobiological understanding of complex conditions Open

Akihiro Koreki, Jessica Eccles, Sarah N. Garfinkel, Hugo Critchley, Sarah Cope , et al. · 2022

We found a significant association between FS and joint hypermobility, which was independent of anxiety and depression.

Mask‐induced ear injury in schizophrenia: A novel complication in the COVID‐19 era Open

Akihiro Koreki, Teruki Koizumi, Kamiyu Ogyu, Yuki Mashima, Kaoru Taguchi , et al. · 2022

Restrictive type and infectious complications might predict nadir hematological values among individuals with anorexia nervosa during the refeeding period: a retrospective study Open

Michitaka Funayama, Akihiro Koreki, Yu Mimura, Taketo Takata, Satoyuki Ogino , et al. · 2022

Effectiveness and Cost-effectiveness of Online Brief Mindfulness-based Cognitive Therapy for the Improvement of Productivity in the Workplace: Study Protocol for a Randomized Controlled Trial Open

Mitsuhiro Sado, Masashi Yamada, Akira Ninomiya, Maki Nagaoka, Naho Goto , et al. · 2022

Background Numerous studies have demonstrated the effectiveness of mindfulness-based programs (MBPs) among both clinical and nonclinical populations. These data document positive impacts in the workplace, including reducing perceived stres…

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