Akihiro Nomoto
YOU?
Author Swipe
View article: Evidence of radiation induced segregation clustering in binary ferritic model alloys
Evidence of radiation induced segregation clustering in binary ferritic model alloys Open
View article: CCDC 2395275: Experimental Crystal Structure Determination
CCDC 2395275: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Bis(methylene)-λ <sup>5</sup> -phosphane anions
Bis(methylene)-λ <sup>5</sup> -phosphane anions Open
Novel anionic phosphorus-centered heteroallene type molecules, bis(methylene)-λ 5 -phosphane anions, were synthesized and fully characterized.
View article: Crystal structure of (μ-hydrogen disulfato)-μ-oxido-bis[(4,4′-di-<i>tert</i>-butyl-2,2′-bipyridine)oxidovanadium(IV/V)] acetonitrile monosolvate
Crystal structure of (μ-hydrogen disulfato)-μ-oxido-bis[(4,4′-di-<i>tert</i>-butyl-2,2′-bipyridine)oxidovanadium(IV/V)] acetonitrile monosolvate Open
The dinuclear oxidovanadium(IV/V) complex, [V 2 (HS 2 O 8 )O 3 (C 18 H 24 N 2 ) 2 ]·CH 3 CN or [V 2 O 2 (μ-O)(μ-H(SO 4 ) 2 )(4,4′- t Bubpy) 2 ]·CH 3 CN (4,4′- t Bubpy = 4,4′-di- tert -butyl-2,2′-bipyridine), has crystallographic C 2 symmet…
View article: Boron Clusters Alter the Membrane Permeability of Dicationic Fluorescent DNA-Staining Dyes
Boron Clusters Alter the Membrane Permeability of Dicationic Fluorescent DNA-Staining Dyes Open
Membrane-permeable fluorescent dyes that stain DNA are useful reagents for microscopic imaging, as they can be introduced into living cells to label DNA. However, the number of these dyes, such as Hoechst 33342, is limited. Here, we show t…
View article: Photodynamic therapy using metal-conjugated novel photosensitizer with the expectation of heavy atom effects
Photodynamic therapy using metal-conjugated novel photosensitizer with the expectation of heavy atom effects Open
Photodynamic therapy (PDT) is a relatively non-invasive anti-cancer therapy that employs a photosensitizer with a specific wavelength of light, causing a photochemical reaction that releases free radicals, thereby inducing tumor cell necro…
View article: Development of Next-generation Glycoconjugated Photosensitizers for Photodynamic Therapy for Clinical Application
Development of Next-generation Glycoconjugated Photosensitizers for Photodynamic Therapy for Clinical Application Open
がん治療における長年の夢は，腫瘍を非侵襲的に治療することにある．近年光線力学療法（Photodynamic therapy: PDT）が，低侵襲性の治療法として注目されている．我々はPDT用の光増感剤の生体適合性と腫瘍選択性の向上を目指して，光増感剤（クロリン，C60等）への糖質（グルコース，マンノース，マルトトリオース等）の導入を立案した．なかでもグルコース連結クロリンe6（G-Ce6）は，in vitroおよびin vivoで優れたPDT効果を示した．さらに，がん発症犬…
View article: Anti-tumor effect of mannose-conjugated chlorin e6 photodynamic therapy targeting M2-like tumor-associated macrophages
Anti-tumor effect of mannose-conjugated chlorin e6 photodynamic therapy targeting M2-like tumor-associated macrophages Open
M2-like tumor-associated macrophages (M2-TAMs) in cancer tissues play a key role in cancer progression and immune evasion. Therefore, cancer immunotherapies targeting M2-TAMs have attracted considerable attention. Photodynamic therapy (PDT…
View article: CCDC 2132957: Experimental Crystal Structure Determination
CCDC 2132957: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Metal-Free Synthesis of 2-Substituted Quinazolines via Green Oxidation of o-Aminobenzylamines: Practical Construction of N-Containing Heterocycles Based on a Salicylic Acid-Catalyzed Oxidation System
Metal-Free Synthesis of 2-Substituted Quinazolines via Green Oxidation of o-Aminobenzylamines: Practical Construction of N-Containing Heterocycles Based on a Salicylic Acid-Catalyzed Oxidation System Open
Conventional quinazoline synthesis methods involve a highly multistep reaction, and often require excess amounts of substrate to control the product selectivity, leading to significant resource wastage. Hence, in this study, from the viewp…
View article: Photoinduced Bisphosphination of Alkynes with Phosphorus Interelement Compounds and Its Application to Double-Bond Isomerization
Photoinduced Bisphosphination of Alkynes with Phosphorus Interelement Compounds and Its Application to Double-Bond Isomerization Open
The addition of interelement compounds with heteroatom-heteroatom single bonds to carbon-carbon unsaturated bonds under light irradiation is believed to be an atomically efficient method to procure materials with carbon-heteroatom bonds. I…
View article: Transition-Metal-Free Synthesis of Unsymmetrical Diaryl Tellurides via SH2 Reaction of Aryl Radicals on Tellurium
Transition-Metal-Free Synthesis of Unsymmetrical Diaryl Tellurides via SH2 Reaction of Aryl Radicals on Tellurium Open
Although diaryl tellurides are parent organotellurium compounds, their synthesis methods, especially for unsymmetrical ones, are limited. This may be due to the instability of diaryl tellurides and their synthesis intermediates under react…
View article: Direct Synthesis and Characterization of Endohedral Zinc(Ii) Hemicryptophane Complex
Direct Synthesis and Characterization of Endohedral Zinc(Ii) Hemicryptophane Complex Open
View article: A two-phase bromination process using tetraalkylammonium hydroxide for the practical synthesis of α-bromolactones from lactones
A two-phase bromination process using tetraalkylammonium hydroxide for the practical synthesis of α-bromolactones from lactones Open
A simple and efficient method for α-brominating lactones that affords α - bromolactones under mild conditions using tetraalkylammonium hydroxide (R 4 N + OH − ) as a base was developed. Lactones are ring-opened with Br 2 and a substoichiom…
View article: Excellent Catalytic Performances of a Au/C–CuO Binary System in the Selective Oxidation of Benzylamines to Imines under Atmospheric Oxygen
Excellent Catalytic Performances of a Au/C–CuO Binary System in the Selective Oxidation of Benzylamines to Imines under Atmospheric Oxygen Open
A green method of the oxidation of benzylamines to imines was developed using a novel binary system of Au/C-CuO. This system was evaluated under atmospheric oxygen, and the corresponding imines were obtained in up to 100% yields by loading…
View article: CCDC 2104238: Experimental Crystal Structure Determination
CCDC 2104238: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Photodynamic therapy using mannose-conjugated chlorin e6 stimulates tumor immunity by increasing cell surface calreticulin in cancer cells and promoting macrophage phagocytosis
Photodynamic therapy using mannose-conjugated chlorin e6 stimulates tumor immunity by increasing cell surface calreticulin in cancer cells and promoting macrophage phagocytosis Open
Photodynamic therapy (PDT) damages cancer cells via photosensitization using harmless laser irradiation. We synthesized a new photosensitizer, mannose-conjugated-chlorin e6 (M-chlorin e6), which targets mannose receptors that are highly ex…
View article: Clarification on the Reactivity of Diaryl Diselenides toward Hexacyclohexyldilead under Light
Clarification on the Reactivity of Diaryl Diselenides toward Hexacyclohexyldilead under Light Open
In this study, the reactivity of organochalcogen compounds toward a representative alkyl-lead bond compound under light was investigated in detail. Under light irradiation, the Cy-Pb bond of Cy6Pb2 (Cy = cyclohexyl) undergoes homolytic cle…
View article: <i>trans</i>-Bis[8-(benzylsulfanyl)quinoline-κ<sup>2</sup> <i>N</i>,<i>S</i>]dichloridocobalt(II)
<i>trans</i>-Bis[8-(benzylsulfanyl)quinoline-κ<sup>2</sup> <i>N</i>,<i>S</i>]dichloridocobalt(II) Open
The title dichlorocobalt(II) complex, trans -[CoCl 2 ( 1 ) 2 ] [ 1 = 8-(benzylsulfanyl)quinoline, C 16 H 13 NS], has a central Co II atom (site symmetry \overline1) that exhibits a distorted octahedral coordination geometry and is coordina…
View article: 2,2-Bis(phenylselanyl)-1-(p-tolyl)vinyl 2-Oxo-2-(p-tolyl)acetate
2,2-Bis(phenylselanyl)-1-(p-tolyl)vinyl 2-Oxo-2-(p-tolyl)acetate Open
2,2-Bis(phenylselanyl)-1-(p-tolyl)vinyl 2-oxo-2-(p-tolyl)acetate was synthesized via the reaction of p-tolylacetylene with diphenyl diselenide and benzoyl peroxide in benzene under atmospheric conditions. The molecular structure of the syn…
View article: Oxidative Synthesis of Acid Blue 7 Dye Catalyzed by CuO/Silicotungstic Acid in Water-Phase
Oxidative Synthesis of Acid Blue 7 Dye Catalyzed by CuO/Silicotungstic Acid in Water-Phase Open
A catalytic oxidation reaction for Acid Blue 7 dye synthesis was evaluated in water. Without lead oxide or manganese oxide derivatives as oxidants, polyoxometalate catalysts were investigated to reduce the usage of harmful heavy metal. A c…
View article: Transition-Metal-Catalyzed Diarylation of Isocyanides with Triarylbismuthines for the Selective Synthesis of Imine Derivatives
Transition-Metal-Catalyzed Diarylation of Isocyanides with Triarylbismuthines for the Selective Synthesis of Imine Derivatives Open
The transition-metal-catalyzed diarylation of isocyanides with triarylbismuthines was investigated in detail, and rhodium catalysts such as [RhCl(nbd)]2 were found to selectively afford N-alkyl diaryl ketimines. On the other hand, palladiu…
View article: 4,4′-Di-tert-butyl-2,2′-bipyridinium Trifluoromethanesulfonate
4,4′-Di-tert-butyl-2,2′-bipyridinium Trifluoromethanesulfonate Open
4,4′-Di-tert-butyl-2,2′-bipyridinium trifluoromethanesulfonate was synthesized by stirring 4,4′-Di-tert-butyl-2,2′-bipyridine with scandium(III) trifluoromethanesulfonate in acetonitrile, followed by precipitation with diethyl ether. The s…
View article: Highly regio- and stereoselective phosphinylphosphination of terminal alkynes with tetraphenyldiphosphine monoxide under radical conditions
Highly regio- and stereoselective phosphinylphosphination of terminal alkynes with tetraphenyldiphosphine monoxide under radical conditions Open
The homolytic cleavage of the P V (O)–P III bond in tetraphenyldiphosphine monoxide simultaneously provides both pentavalent and trivalent phosphorus-centered radicals with different reactivities. The method using V-40 as an initiator is s…
View article: Maltotriose–Chlorin e6 Conjugate Linked <i>via</i> Tetraethyleneglycol as an Advanced Photosensitizer for Photodynamic Therapy. Synthesis and Antitumor Activities against Canine and Mouse Mammary Carcinoma Cells
Maltotriose–Chlorin e6 Conjugate Linked <i>via</i> Tetraethyleneglycol as an Advanced Photosensitizer for Photodynamic Therapy. Synthesis and Antitumor Activities against Canine and Mouse Mammary Carcinoma Cells Open
Glycoconjugated chlorins represent a promising class of compounds that meet the requirements for the third-generation photosensitizer (PS) for photodynamic therapy (PDT). We have focused on the use of glucose (Glc) to improve the performan…
View article: Potential of Photodynamic Therapy Based on Sugar-Conjugated Photosensitizers
Potential of Photodynamic Therapy Based on Sugar-Conjugated Photosensitizers Open
In 2015, the Japanese health insurance approved the use of a second-generation photodynamic therapy (PDT) using talaporfin sodium (TS); however, its cancer cell selectivity and antitumor effects of TS PDT are not comprehensive. The Warburg…
View article: Photodynamic therapy exploiting the anti-tumor activity of mannose-conjugated chlorin e6 reduced M2-like tumor-associated macrophages
Photodynamic therapy exploiting the anti-tumor activity of mannose-conjugated chlorin e6 reduced M2-like tumor-associated macrophages Open
View article: Large-Scale Synthesis of Thio-glucose-Conjugated Chlorin e6 for Photodynamic Therapy
Large-Scale Synthesis of Thio-glucose-Conjugated Chlorin e6 for Photodynamic Therapy Open
Chlorin e6 is a heterocycle exhibiting spectral absorption in the 600-700 nm wavelength range used for photodynamic therapy (PDT).Herein, a sugar-conjugated chlorin e6 derivative was synthesized on a large scale.An alkyl spacer was fabrica…
View article: Au/Ag/Cu-Mixed Catalysts for the Eco-Friendly Oxidation of 5-Hydroxymethylfurfural and Related Compounds to Carboxylic Acids under Atmospheric Oxygen in Water
Au/Ag/Cu-Mixed Catalysts for the Eco-Friendly Oxidation of 5-Hydroxymethylfurfural and Related Compounds to Carboxylic Acids under Atmospheric Oxygen in Water Open
A green method for the oxidation of alcohols to carboxylic acids was developed using a novel co-catalytic system based on gold, silver, and copper catalysts. This reaction system was conducted under atmospheric oxygen in water and mild con…
View article: CCDC 1454737: Experimental Crystal Structure Determination
CCDC 1454737: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …