Akira Oguma
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View article: High Airway‐To‐Vessel Volume Ratio and Visual Bronchiectasis Are Associated With Exacerbations in <scp>COPD</scp>
High Airway‐To‐Vessel Volume Ratio and Visual Bronchiectasis Are Associated With Exacerbations in <span>COPD</span> Open
Background and Objective The effects of the volume mismatch between the airway and lung vasculature on exacerbation in chronic obstructive pulmonary disease (COPD) is uncertain. We aimed to examine the association between an increased volu…
View article: Determinants of airway morphology in asthma: Inflammatory and noninflammatory factors
Determinants of airway morphology in asthma: Inflammatory and noninflammatory factors Open
View article: Relationships of computed tomography-based small vessel indices of the lungs with ventilation heterogeneity and high transfer coefficients in non-smokers with asthma
Relationships of computed tomography-based small vessel indices of the lungs with ventilation heterogeneity and high transfer coefficients in non-smokers with asthma Open
Background: The mechanism of high transfer coefficients of the lungs for carbon monoxide (Kco) in non-smokers with asthma is explained by the redistribution of blood flow to the area with preserved ventilation, to match the ventilation per…
View article: Stronger Associations of Centrilobular Than Paraseptal Emphysema With Longitudinal Changes in Diffusing Capacity and Mortality in COPD
Stronger Associations of Centrilobular Than Paraseptal Emphysema With Longitudinal Changes in Diffusing Capacity and Mortality in COPD Open
View article: Blood eosinophil count variability in chronic obstructive pulmonary disease and severe asthma
Blood eosinophil count variability in chronic obstructive pulmonary disease and severe asthma Open
We identified variations in the blood eosinophil counts and their contributing factors in patients with COPD and severe asthma.
View article: Differential role of mucus plugs in asthma: Effects of smoking and association with airway inflammation
Differential role of mucus plugs in asthma: Effects of smoking and association with airway inflammation Open
The association of mucus plug score with exacerbation frequency and reduced lung function may vary due to airway inflammatory profile and smoking status in asthma.
View article: Subtyping emphysematous COPD by respiratory volume change distributions on CT
Subtyping emphysematous COPD by respiratory volume change distributions on CT Open
Background There is considerable heterogeneity among patients with emphysematous chronic obstructive pulmonary disease (COPD). We hypothesised that in addition to emphysema severity, ventilation distribution in emphysematous regions would …
View article: Further evidence for association of YKL-40 with severe asthma airway remodeling
Further evidence for association of YKL-40 with severe asthma airway remodeling Open
View article: Association of abdominal visceral adiposity with sputum IL-5 levels in asthma
Association of abdominal visceral adiposity with sputum IL-5 levels in asthma Open
View article: Parenchymal destruction in asthma: Fixed airflow obstruction and lung function trajectory
Parenchymal destruction in asthma: Fixed airflow obstruction and lung function trajectory Open
View article: Combined assessment of pulmonary arterial enlargement and coronary calcification predicts the prognosis of patients with chronic obstructive pulmonary disease
Combined assessment of pulmonary arterial enlargement and coronary calcification predicts the prognosis of patients with chronic obstructive pulmonary disease Open
View article: Clinical Impact of Mucus Plugs in Eosinophilic Asthma
Clinical Impact of Mucus Plugs in Eosinophilic Asthma Open
View article: Emphysema Subtypes and Longitudinal Changes in Airflow Limitation and Diffusion Capacity in Patients with Chronic Obstructive Pulmonary Disease
Emphysema Subtypes and Longitudinal Changes in Airflow Limitation and Diffusion Capacity in Patients with Chronic Obstructive Pulmonary Disease Open
Rationale] Emphysema is a major pathology of chronic obstructive pulmonary disease (COPD), and is classified into centrilobular emphysema (CLE), paraseptal emphysema (PSE) and panlobular emphysema.Although these subtypes, particularly CLE …
View article: Lung Contractive Change in Severe Acute Respiratory Failure Requiring Invasive Ventilation; A Comparison of Features Between Interstitial Lung Disease and Severe Infection
Lung Contractive Change in Severe Acute Respiratory Failure Requiring Invasive Ventilation; A Comparison of Features Between Interstitial Lung Disease and Severe Infection Open
Background: Generally, the incidence of irreversible lung injury is considered to be higher in acute respiratory failure due to interstitial lung disease (ILD), compared to those due to severe infection. However, those sub-phenotypes, whic…
View article: Central airway and peripheral lung structures in airway disease-dominant COPD
Central airway and peripheral lung structures in airway disease-dominant COPD Open
The concept that the small airway is a primary pathological site for all COPD phenotypes has been challenged by recent findings that the disease starts from the central airways in COPD subgroups and that a smaller central airway tree incre…
View article: Contributions of Emphysema and Small Airway Diseases Assessed by CT to Predict FEV<sub>1</sub> Decline in Patients with COPD
Contributions of Emphysema and Small Airway Diseases Assessed by CT to Predict FEV<sub>1</sub> Decline in Patients with COPD Open