Akira Takahashi
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View article: 'Studies for': A Human-AI Co-Creative Sound Artwork Using a Real-time Multi-channel Sound Generation Model
'Studies for': A Human-AI Co-Creative Sound Artwork Using a Real-time Multi-channel Sound Generation Model Open
This paper explores the integration of AI technologies into the artistic workflow through the creation of Studies for, a generative sound installation developed in collaboration with sound artist Evala (https://www.ntticc.or.jp/en/archive/…
View article: Temporal and Demographic Trends in Biopsy-Proven Kidney Disease Diagnoses in the Southwestern United States, 1993-2022
Temporal and Demographic Trends in Biopsy-Proven Kidney Disease Diagnoses in the Southwestern United States, 1993-2022 Open
Rationale & Objective: Kidney biopsy is vital to diagnose and manage medical kidney diseases. However, not many large-scale studies for medical kidney disease have been reported worldwide. We describe 30-year temporal and demographic trend…
View article: Abemaciclib-associated acute interstitial nephritis successfully treated with glucocorticoids: a case report and literature review
Abemaciclib-associated acute interstitial nephritis successfully treated with glucocorticoids: a case report and literature review Open
Background Drug-induced acute interstitial nephritis (DI-AIN) is the most common type of AIN. DI-AIN occurs when medications trigger a T cell-mediated immune response that promotes tubulitis and interstitial inflammation with eosinophils, …
View article: Proliferative Glomerulonephritis With Monoclonal Immunoglobulin G Deposits (PGNMID) With Chronic-Type Thrombotic Microangiopathy (TMA): A Case Report
Proliferative Glomerulonephritis With Monoclonal Immunoglobulin G Deposits (PGNMID) With Chronic-Type Thrombotic Microangiopathy (TMA): A Case Report Open
Proliferative glomerulonephritis with monoclonal immunoglobulin G (IgG) deposits (PGNMID) is a form of monoclonal gammopathy of renal significance. A pathological evaluation of a kidney biopsy is essential for the diagnosis of PGNMID becau…
View article: Targeting <scp>MLL1</scp> / <scp>WDR5</scp> ‐Mediated Epigenetic Regulation Mitigates Peritoneal Fibrosis by Reducing <scp> p16 <sup>INK4a</sup> </scp>
Targeting <span>MLL1</span> / <span>WDR5</span> ‐Mediated Epigenetic Regulation Mitigates Peritoneal Fibrosis by Reducing <span> p16 <sup>INK4a</sup> </span> Open
Peritoneal fibrosis poses a significant challenge to the long‐term efficacy of peritoneal dialysis (PD), with emerging evidence highlighting the role of cellular senescence in its pathogenesis. p16 INK4a is a cell cycle regulator that has …
View article: Peritoneal dialysis-associated polymicrobial peritonitis with slow onset after root canal treatment: the first case and review of the literature
Peritoneal dialysis-associated polymicrobial peritonitis with slow onset after root canal treatment: the first case and review of the literature Open
View article: Polycythemia secondary to bilaterally enlarged kidneys in T-Cell acute lymphoblastic leukemia: a case report and literature review
Polycythemia secondary to bilaterally enlarged kidneys in T-Cell acute lymphoblastic leukemia: a case report and literature review Open
We report a case of marked hypertension and secondary polycythemia induced by severe renal infiltration of T-ALL at diagnosis, which were synchronically improved with induction chemotherapy. This case history suggests the importance of con…
View article: Selective activation of PPARα by pemafibrate mitigates peritoneal inflammation and fibrosis through suppression of NLRP3 inflammasome and modulation of inflammation
Selective activation of PPARα by pemafibrate mitigates peritoneal inflammation and fibrosis through suppression of NLRP3 inflammasome and modulation of inflammation Open
Peritoneal inflammation and fibrosis remain major challenges to the long-term maintenance of peritoneal dialysis. Pemafibrate, a selective peroxisome proliferator-activated receptor α (PPARα) modulator, has been implicated in the managemen…
View article: Successful treatment of severe renal failure caused by malignant hypertension using a combination of renin–angiotensin–aldosterone system inhibitors: a case report
Successful treatment of severe renal failure caused by malignant hypertension using a combination of renin–angiotensin–aldosterone system inhibitors: a case report Open
Marked activation of the renin–angiotensin–aldosterone system (RAAS) plays an important role in malignant hypertension (MHT) by worsening hypertension and renal function. The rates of readmission for severe hypertension and cardiovascular …
View article: SpecMaskGIT: Masked Generative Modeling of Audio Spectrograms for Efficient Audio Synthesis and Beyond
SpecMaskGIT: Masked Generative Modeling of Audio Spectrograms for Efficient Audio Synthesis and Beyond Open
Recent advances in generative models that iteratively synthesize audio clips sparked great success to text-to-audio synthesis (TTA), but with the cost of slow synthesis speed and heavy computation. Although there have been attempts to acce…
View article: Peritoneal dialysis-associated peritonitis, caused by superior mesenteric artery thrombosis with intestinal necrosis: a case report
Peritoneal dialysis-associated peritonitis, caused by superior mesenteric artery thrombosis with intestinal necrosis: a case report Open
View article: Selective Activation of PPARα Mitigates Peritoneal Inflammation and Fibrosis through NLRP3 Inflammasome Suppression and Inflammation Modulation
Selective Activation of PPARα Mitigates Peritoneal Inflammation and Fibrosis through NLRP3 Inflammasome Suppression and Inflammation Modulation Open
Peritoneal inflammation and fibrosis remain major challenges to the long-term maintenance of peritoneal dialysis. Pemafibrate, a selective peroxisome proliferator-activated receptor α (PPARα) modulator, has been implicated in the managemen…
View article: Comparison between the 0- and 30-s balloon dilation time in percutaneous transluminal angioplasty for restenosed arteriovenous fistula among hemodialysis patients: a multicenter, prospective, randomized trial (CARP study)
Comparison between the 0- and 30-s balloon dilation time in percutaneous transluminal angioplasty for restenosed arteriovenous fistula among hemodialysis patients: a multicenter, prospective, randomized trial (CARP study) Open
View article: Successful treatment of severe renal failure caused by malignant hypertension using a combination of renin-angiotensin-aldosterone system inhibitors: a case report
Successful treatment of severe renal failure caused by malignant hypertension using a combination of renin-angiotensin-aldosterone system inhibitors: a case report Open
Background: Marked activation of the renin-angiotensin-aldosterone system (RAAS) plays an important role in hypertensive emergencies, in particular malignant hypertension, by worsening hypertension and renal function. The rates of readmiss…
View article: Plasma Kynurenine Level is Associated With Left DLPFC Activity and Can Predict Treatment Response in Major Depressive Disorder
Plasma Kynurenine Level is Associated With Left DLPFC Activity and Can Predict Treatment Response in Major Depressive Disorder Open
To establish treatment response biomarkers that reflect the pathophysiology of depression, it is important to use an integrated set of features that are promising as biomarkers. This study aimed to determine the relationship between blood …
View article: The histopathological spectrum of kidney biopsies in patients with thymoma and myasthenia gravis: a report of 24 biopsies from a single institution
The histopathological spectrum of kidney biopsies in patients with thymoma and myasthenia gravis: a report of 24 biopsies from a single institution Open
Background Nephropathy in patients with thymic diseases such as thymoma and myasthenia gravis (MG) is rare and has been described mostly as isolated case reports. Here we evaluate a series of kidney biopsies from patients with thymoma and/…
View article: A case of iatrogenic air bubbles in the left ventricle by coronary computed tomographic angiography
A case of iatrogenic air bubbles in the left ventricle by coronary computed tomographic angiography Open
We report a case of asymptomatic iatrogenic air bubbles in the left ventricle observed by coronary computed tomographic angiography. Air bubbles are rarely found in the left ventricle and could prove fatal should they migrate to the brain …
View article: A Case of Delayed Symptomatic Vasospasm after Surgical Clipping of an Unruptured Intracranial Aneurysm
A Case of Delayed Symptomatic Vasospasm after Surgical Clipping of an Unruptured Intracranial Aneurysm Open
Although intracranial arterial vasospasm commonly occurs after subarachnoid hemorrhage, delayed symptomatic vasospasm rarely occurs after surgical clipping of unruptured intracranial aneurysms. We report the case of a 67-year-old woman who…
View article: Three-Dimensional J-Integral Based on a Domain Integral Method for Non-Homogeneous Solid with Residual Stresses Undergoing Large Deformation
Three-Dimensional J-Integral Based on a Domain Integral Method for Non-Homogeneous Solid with Residual Stresses Undergoing Large Deformation Open
In this paper, a new three-dimensional J-integral for non-homogeneous solids undergoing large deformation and associated with residual stresses is presented. The formulation of J-integral involves the strain energy density W ... | Find, re…
View article: P6075OCT guided excimer laser coronary angioplasty for in-stent restenosis
P6075OCT guided excimer laser coronary angioplasty for in-stent restenosis Open
Background: Late adverse events lead to concern on long-term efficacy of drueluting stents (DES).The clear mechanism of late in-stent restenosis (ISR) remains unclear.Sustained hypersensitivity reaction played an important role in the form…
View article: Cardiac Tamponade Provoked by a Subphrenic Abscess
Cardiac Tamponade Provoked by a Subphrenic Abscess Open
A 66-year-old man with a 2-month history of epigastralgia was referred to our hospital after developing shock.An echocardiogram revealed a large pericardial echo-free space with collapsed right ventricle.A computed tomography scan of his t…
View article: Imaging Follow-up after Carotid Artery Stenting with Carotid Wallstent Using Computed Tomographic Angiography
Imaging Follow-up after Carotid Artery Stenting with Carotid Wallstent Using Computed Tomographic Angiography Open
Computed tomography angiography (CTA) is useful for postoperative evaluation of restenosis and plaque protrusion after carotid artery stenting (CAS). However, stent artifacts are a common problem in the evaluation of CTA images, which are …
View article: Utility of ultrasonography examination in carotid artery stenting using Mo.Ma Ultra
Utility of ultrasonography examination in carotid artery stenting using Mo.Ma Ultra Open
Purpose: The aim of this study was to investigate the usefulness of ultrasonography (US) in carotid artery stenting (CAS) using Mo.Ma Ultra. Methods: We included 49 consecutive patients who underwent CAS using Mo.Ma Ultra. Thirty-five pati…
View article: Central Retinal Artery Occlusion after the Endovascular Treatment of Unruptured Ophthalmic Artery Aneurysm: A Case Report and a Literature Review
Central Retinal Artery Occlusion after the Endovascular Treatment of Unruptured Ophthalmic Artery Aneurysm: A Case Report and a Literature Review Open
Endovascular coil embolization for ophthalmic artery (OphA) aneurysms has a risk of occlusion of the OphA, which can lead to loss of vision. The authors report a patient with unruptured OphA aneurysm which treated with endovascular coiling…
View article: Efficacy of Endovascular Treatment for Occlusive Lesions of a Single M2 Branch in Non-recombinant Tissue Plasminogen Activator Treated Patients
Efficacy of Endovascular Treatment for Occlusive Lesions of a Single M2 Branch in Non-recombinant Tissue Plasminogen Activator Treated Patients Open
Purpose: This study investigated the efficacy of endovascular therapy for occlusion of the second segment (M2) of the middle cerebral artery (MCA) in patients who were ineligible for intravenous thrombolysis with recombinant tissue plasmin…
View article: Hypertension and Estrogen Deficiency Augment Aneurysmal Remodeling in the Rabbit Circle of Willis in Response to Carotid Ligation
Hypertension and Estrogen Deficiency Augment Aneurysmal Remodeling in the Rabbit Circle of Willis in Response to Carotid Ligation Open
Increased cerebral blood flow has been shown to induce pathological structural changes in the Circle of Willis (CoW) in experimental models. Previously, we reported flow‐induced aneurysm‐like remodeling in the CoW secondary to flow redistr…
View article: A case of dural arteriovenous fistula of right cavernous sinus presenting bilateral eye symptoms
A case of dural arteriovenous fistula of right cavernous sinus presenting bilateral eye symptoms Open
An 85-year-old woman was first admitted to our hospital because of right ptosis and diplopia. Examinations showed right oculomotor paralysis and reduced vision in the right eye. Serological and neuroradiological examinations failed to reve…
View article: Use of Dual Energy Computed Tomography Imaging to follow up Stent-assisted Coil Embolization
Use of Dual Energy Computed Tomography Imaging to follow up Stent-assisted Coil Embolization Open
コイル塞栓術後フォローアップにCTAを用いることはartifactの問題があり, 困難であった. Dual energy CTを用いることにより, 単色X線画像が算出可能となり, ビームハードニング効果を抑制できるようになった. さらに, エネルギーサブトラクション処理を用い, 塞栓コイルの消去と造影剤の高いCT値の確保を行うことにより, コイル近傍の造影剤の画像化が可能となり, 塞栓術後再開通の評価が実現した. また, エネルギーを最適化することより, ステントの描出もよ…