Akmal Hidayat Bin Sabri
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View article: Corrigendum to “Metronidazole nanosuspension loaded dissolving microarray patches: An engineered composite pharmaceutical system for the treatment of skin and soft tissue infection” [Biomater. Adv. 140 (September 2022) 213073]
Corrigendum to “Metronidazole nanosuspension loaded dissolving microarray patches: An engineered composite pharmaceutical system for the treatment of skin and soft tissue infection” [Biomater. Adv. 140 (September 2022) 213073] Open
View article: Corrigendum to “Dissolvable microarray patches of levodopa and carbidopa for Parkinson’s disease management” [Eur. J. Pharm. Biopharm. 199 (2024) 114304]
Corrigendum to “Dissolvable microarray patches of levodopa and carbidopa for Parkinson’s disease management” [Eur. J. Pharm. Biopharm. 199 (2024) 114304] Open
View article: Correction to “Schizophrenia Treatment Based on Sustained Release of Risperidone from Poly(lactic- <i>co</i> -glycolic) Acid Implantable Microarray Patch “
Correction to “Schizophrenia Treatment Based on Sustained Release of Risperidone from Poly(lactic- <i>co</i> -glycolic) Acid Implantable Microarray Patch “ Open
View article: A trilayer microneedle patch for transdermal delivery of the peptide salmon calcitonin for osteoporosis therapy
A trilayer microneedle patch for transdermal delivery of the peptide salmon calcitonin for osteoporosis therapy Open
Lipid-based nanocarrier systems have multiple advantages, including biocompatibility, biodegradability and drug loading capacity. Combining these findings with the concept of dissolving microneedles (MNs) would aid in the efficient deliver…
View article: Author Correction: Microneedle-based biosensing
Author Correction: Microneedle-based biosensing Open
View article: Lymphatic-targeted amphotericin B nanocrystals delivered using microarray patches applied to cutaneous leishmaniasis
Lymphatic-targeted amphotericin B nanocrystals delivered using microarray patches applied to cutaneous leishmaniasis Open
Leishmaniasis, a parasitic disease transmitted by female sandflies, primarily affects impoverished populations in tropical and subtropical regions. Cutaneous leishmaniasis (CL) is the most prevalent form, with over 600,000 new cases annual…
View article: Development, Evaluation, and Characterization of a Novel Mucoadhesive Film Containing <i>Pterodon pubescens</i> Benth Ethanolic Extract for Dental Use
Development, Evaluation, and Characterization of a Novel Mucoadhesive Film Containing <i>Pterodon pubescens</i> Benth Ethanolic Extract for Dental Use Open
Periodontal diseases involve infectious and inflammatory processes that affect oral tissues. Extracts from Pterodon pubescens Benth (sucupira) have demonstrated antinociceptive, anti‐inflammatory, anti‐edematogenic, and antiplatelet effect…
View article: Immunomodulator loaded microneedle arrays for targeted intradermal drug delivery to skin tumors
Immunomodulator loaded microneedle arrays for targeted intradermal drug delivery to skin tumors Open
Topical therapy with imiquimod in a cream [5% w/w imiquimod cream (Aldara™)] for the treatment of nodular basal cell carcinoma (BCC) currently results in low cure rates, attributed to low imiquimod permeation. Herein we have developed nove…
View article: Bimodal Dissolving Microneedles with Nanoparticle Coating and Encapsulation for Extended Dual‐Drug Delivery
Bimodal Dissolving Microneedles with Nanoparticle Coating and Encapsulation for Extended Dual‐Drug Delivery Open
Effective co‐delivery of multiple drugs via microneedle (MN) platforms is challenging due to limited loading capacity and the need for sustained release. This study presents a bimodal coated‐dissolving microneedle (DMN) patch for extended …
View article: Molecular Biointerface Characterisation For An Implanted Medical Device Using Cryogenic Orbitrap Secondary Ion Mass Spectrometry (Cryo-OrbiSIMS)
Molecular Biointerface Characterisation For An Implanted Medical Device Using Cryogenic Orbitrap Secondary Ion Mass Spectrometry (Cryo-OrbiSIMS) Open
Implanted medical devices often fail due to foreign body reaction (FBR), a process still not fully understood. This study examines silicone rubber poly(dimethyl siloxane) catheters implanted in mice for 1 and 28 days. Cryo-OrbiSIMS was use…
View article: Lyophilised reservoirs in combination with hydrogel-forming microarray patches for transdermal delivery of isoniazid and pyridoxine hydrochloride
Lyophilised reservoirs in combination with hydrogel-forming microarray patches for transdermal delivery of isoniazid and pyridoxine hydrochloride Open
View article: Schizophrenia Treatment Based on Sustained Release of Risperidone from Poly(lactic-<i>co</i>-glycolic) Acid Implantable Microarray Patch
Schizophrenia Treatment Based on Sustained Release of Risperidone from Poly(lactic-<i>co</i>-glycolic) Acid Implantable Microarray Patch Open
Schizophrenia is one of the most severe mental disorders, affecting approximately 24 million people worldwide. Conventional treatments, such as drug-loaded implants and intramuscular injections, have several limitations, including pain dur…
View article: Delivery of Islatravir via High Drug‐Load, Long‐acting Microarray Patches for the Prevention or Treatment of Human Immunodeficiency Virus
Delivery of Islatravir via High Drug‐Load, Long‐acting Microarray Patches for the Prevention or Treatment of Human Immunodeficiency Virus Open
This research focuses on developing and characterizing islatravir‐loaded dissolving microarray patches (MAPs) to provide an effective, minimally invasive treatment option for human immunodeficiency virus (HIV‐1) prevention and treatment. T…
View article: Evaluation of physical and chemical modifications to drug reservoirs for stimuli-responsive microneedles
Evaluation of physical and chemical modifications to drug reservoirs for stimuli-responsive microneedles Open
View article: Sodium Alginate Microneedles Loaded with Vancomycin for Skin Infections
Sodium Alginate Microneedles Loaded with Vancomycin for Skin Infections Open
Background: Skin and soft tissue infections (SSTIs) present significant treatment challenges. These infections often require systemic antibiotics such as vancomycin, which poses a risk for increased bacterial resistance. Topical treatments…
View article: Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers
Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers Open
Transdermal drug delivery has been an increasingly studied alternative drug administration route owing to the large surface area of the skin, enabling ease of access and application. Among the various transdermal drug delivery technologies…
View article: Enhanced long-acting simvastatin delivery via effervescent powder-carrying hollow microneedles and nanocrystal-loaded microneedles
Enhanced long-acting simvastatin delivery via effervescent powder-carrying hollow microneedles and nanocrystal-loaded microneedles Open
Hyperlipidemia and its associated cardiovascular complications are the major causes of mortality and disability worldwide. Simvastatin (SIM) is one of the most commonly prescribed lipid-lowering drugs for the treatment of hyperlipidemia by…
View article: Transdermal delivery of bisphosphonates using dissolving and hydrogel-forming microarray patches: Potential for enhanced treatment of osteoporosis
Transdermal delivery of bisphosphonates using dissolving and hydrogel-forming microarray patches: Potential for enhanced treatment of osteoporosis Open
View article: Novel lipid nanovesicle-loaded dissolving microarray patches for fenretinide in breast cancer chemoprevention
Novel lipid nanovesicle-loaded dissolving microarray patches for fenretinide in breast cancer chemoprevention Open
View article: PAMAM dendrimers as mediators of dermal and transdermal drug delivery: a review
PAMAM dendrimers as mediators of dermal and transdermal drug delivery: a review Open
Objectives Poly(amidoamine) dendrimers have been widely investigated as potential nanomaterials that can enhance the skin permeation of topically applied drugs. This article reviews the studies that have used dendrimers as penetration enha…
View article: Development of Norelgestromin Dissolving Bilayer Microarray Patches for Sustained Release of Hormonal Contraceptive
Development of Norelgestromin Dissolving Bilayer Microarray Patches for Sustained Release of Hormonal Contraceptive Open
Microarray patches (MAPs) offer a noninvasive and patient-friendly drug delivery method, suitable for self-administration, which is especially promising for low- and middle-income country settings. This study focuses on the development of …
View article: Risperidone-cyclodextrin complex reservoir combined with hydrogel-forming microneedle array patches for enhanced transdermal delivery
Risperidone-cyclodextrin complex reservoir combined with hydrogel-forming microneedle array patches for enhanced transdermal delivery Open
Hydrogel-forming microneedle array patches (HFMAPs) are microneedles that create microconduits upon insertion and swelling in the skin, potentially allowing prolonged drug delivery without generating sharps waste. Delivering hydrophobic dr…
View article: Dissolving microarray patches loaded with a rotigotine nanosuspension: A potential alternative to Neupro® patch
Dissolving microarray patches loaded with a rotigotine nanosuspension: A potential alternative to Neupro® patch Open
Parkinson's disease (PD), affecting about ten million people globally, presents a significant health challenge. Rotigotine (RTG), a dopamine agonist, is currently administered as a transdermal patch (Neupro®) for PD treatment, but the dail…
View article: Dissolving microarray patches for transdermal delivery of risperidone for schizophrenia management
Dissolving microarray patches for transdermal delivery of risperidone for schizophrenia management Open
Schizophrenia is a psychiatric disorder that results from abnormal levels of neurotransmitters in the brain. Risperidone (RIS) is a common drug prescribed for the treatment of schizophrenia. RIS is a hydrophobic drug that is typically admi…
View article: Systemic delivery of bictegravir and tenofovir alafenamide using dissolving microneedles for HIV preexposure prophylaxis
Systemic delivery of bictegravir and tenofovir alafenamide using dissolving microneedles for HIV preexposure prophylaxis Open
Human immunodeficiency virus (HIV) continues to pose a serious threat to global health. Oral preexposure prophylaxis (PrEP), considered highly effective for HIV prevention, is the utilisation of antiretroviral (ARV) drugs before HIV exposu…
View article: Poly(acrylic acid)/Poly(vinyl alcohol) Microarray Patches for Continuous Transdermal Delivery of Levodopa and Carbidopa: In Vitro and In Vivo Studies
Poly(acrylic acid)/Poly(vinyl alcohol) Microarray Patches for Continuous Transdermal Delivery of Levodopa and Carbidopa: In Vitro and In Vivo Studies Open
Levodopa (LD) has been the most efficacious medication and the gold standard therapy for Parkinson’s disease (PD) for decades. However, its long-term administration is usually associated with motor complications, which are believed to be t…
View article: Novel nano-in-micro fabrication technique of diclofenac nanoparticles loaded microneedle patches for localised and systemic drug delivery
Novel nano-in-micro fabrication technique of diclofenac nanoparticles loaded microneedle patches for localised and systemic drug delivery Open
Diclofenac, a nonsteroidal anti-inflammatory drug, is commonly prescribed for managing osteoarthritis, rheumatoid arthritis, and post-surgical pain. However, oral administration of diclofenac often leads to adverse effects. This study intr…
View article: Dissolvable microarray patches of levodopa and carbidopa for Parkinson’s disease management
Dissolvable microarray patches of levodopa and carbidopa for Parkinson’s disease management Open
Carbidopa and levodopa remain the established therapeutic standard for managing Parkinson's disease. Nevertheless, their oral administration is hindered by rapid enzymatic degradation and gastrointestinal issues, limiting their efficacy, a…
View article: Transdermal Delivery of Pramipexole Using Microneedle Technology for the Potential Treatment of Parkinson’s Disease
Transdermal Delivery of Pramipexole Using Microneedle Technology for the Potential Treatment of Parkinson’s Disease Open
Parkinson's disease (PD) is a debilitating neurodegenerative disease primarily impacting neurons responsible for dopamine production within the brain. Pramipexole (PRA) is a dopamine agonist that is currently available in tablet form. Howe…
View article: A Bilayer Microarray Patch (MAP) for HIV Pre-Exposure Prophylaxis: The Role of MAP Designs and Formulation Composition in Enhancing Long-Acting Drug Delivery
A Bilayer Microarray Patch (MAP) for HIV Pre-Exposure Prophylaxis: The Role of MAP Designs and Formulation Composition in Enhancing Long-Acting Drug Delivery Open
Microarray patches (MAPs) have shown great potential for efficient and patient-friendly drug delivery through the skin; however, improving their delivery efficiency for long-acting drug release remains a significant challenge. This researc…