Ashraf Fawzy
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View article: Clinico- laboratory assessment of infantile cholestasis in Fayoum University Hospital
Clinico- laboratory assessment of infantile cholestasis in Fayoum University Hospital Open
View article: Validation of the Arabic version of the Neck Pain and Disability Scale in patients with chronic neck pain
Validation of the Arabic version of the Neck Pain and Disability Scale in patients with chronic neck pain Open
Background Neck pain significantly contributes to physical disability and interferes with daily functioning and cognitive performance. The Neck Pain and Disability Scale (NPAD) is widely used to assess the severity of neck pain and its bro…
View article: Peritoneal dialysis in Qatar: A model of innovation and excellence
Peritoneal dialysis in Qatar: A model of innovation and excellence Open
View article: Standard Risk Scores Inadequately Estimate Subclinical Coronary Artery Disease in Chronic Obstructive Pulmonary Disease
Standard Risk Scores Inadequately Estimate Subclinical Coronary Artery Disease in Chronic Obstructive Pulmonary Disease Open
View article: Perceived Stress is Associated with Health Outcomes, Platelet Activation, and Oxidative Stress in COPD
Perceived Stress is Associated with Health Outcomes, Platelet Activation, and Oxidative Stress in COPD Open
Among former smokers with COPD, higher perceived stress is associated with worse respiratory outcomes. Platelet activation and oxidative stress may be biological pathways through which perceived stress plays a role in COPD.
View article: Iron Deficiency and All-Cause Hospitalization Risk in a Clinical Cohort of COPD
Iron Deficiency and All-Cause Hospitalization Risk in a Clinical Cohort of COPD Open
Iron deficiency may be associated with adverse outcomes in the absence of anemia, with non-anemic women being a COPD sub-population particularly sensitive to iron deficiency.
View article: Prevalence of Inpatient Pulse Oximetry in Operative and Nonoperative Settings
Prevalence of Inpatient Pulse Oximetry in Operative and Nonoperative Settings Open
View article: Kaposi Sarcoma Involving Kidney Allografts: A Report of Two Cases From Qatar and Literature Review
Kaposi Sarcoma Involving Kidney Allografts: A Report of Two Cases From Qatar and Literature Review Open
Immunosuppression in kidney transplantation elevates the risk of malignancies, particularly immune-driven and virus-related cancers like Kaposi sarcoma (KS). KS typically manifests as single or multiple skin lesions following kidney transp…
View article: Higher Plasma Omega-3 Levels are Associated With Improved Exacerbation Risk and Respiratory-Specific Quality of Life in COPD
Higher Plasma Omega-3 Levels are Associated With Improved Exacerbation Risk and Respiratory-Specific Quality of Life in COPD Open
Plasma EPA+DHA levels are associated with better respiratory-specific quality of life and lower odds of moderate exacerbations in patients with moderate-to-severe COPD. Further research is warranted to investigate the efficacy of an omega-…
View article: Impact of COVID-19 Vaccine Rollout on Mental Health, Social Determinants of Health, and Attitudes Among Individuals With COPD
Impact of COVID-19 Vaccine Rollout on Mental Health, Social Determinants of Health, and Attitudes Among Individuals With COPD Open
Despite a trend towards less social isolation following broad availability of COVID-19 vaccines, individuals with COPD reported worse symptoms, and greater anxiety and depressive symptoms compared to the prevaccine period.
View article: Skin Pigmentation and Pulse Oximeter Accuracy in the Intensive Care Unit: a Pilot Prospective Study
Skin Pigmentation and Pulse Oximeter Accuracy in the Intensive Care Unit: a Pilot Prospective Study Open
Rationale Despite multiple reports of pulse oximeter inaccuracy among hospitalized Black individuals, regulatory testing of pulse oximeters is performed on healthy volunteers. Objective Evaluate pulse oximeter accuracy among intensive care…
View article: Food Insecurity is Associated With COPD Morbidity and Perceived Stress
Food Insecurity is Associated With COPD Morbidity and Perceived Stress Open
Among former smokers with COPD, food insecurity was associated with a higher incidence of exacerbations, worse patient-reported outcomes, and higher perceived stress. Subdomains of food insecurity were independently associated with worse p…
View article: Pulse Oximetry Misclassifies Need for Long-Term Oxygen Therapy in Chronic Obstructive Pulmonary Disease
Pulse Oximetry Misclassifies Need for Long-Term Oxygen Therapy in Chronic Obstructive Pulmonary Disease Open
View article: Diffusing Capacity as a Predictor of Hospitalizations in a Clinical Cohort of Chronic Obstructive Pulmonary Disease
Diffusing Capacity as a Predictor of Hospitalizations in a Clinical Cohort of Chronic Obstructive Pulmonary Disease Open
Rationale: Chronic obstructive pulmonary disease (COPD) hospitalizations are a major burden on patients. Diffusing capacity of the lung for carbon monoxide (DlCO) is a potential predictor that has not been studied in larg…
View article: Clinical Outcomes Associated With Overestimation of Oxygen Saturation by Pulse Oximetry in Patients Hospitalized With COVID-19
Clinical Outcomes Associated With Overestimation of Oxygen Saturation by Pulse Oximetry in Patients Hospitalized With COVID-19 Open
Importance Many pulse oximeters have been shown to overestimate oxygen saturation in persons of color, and this phenomenon has potential clinical implications. The relationship between overestimation of oxygen saturation with timing of COV…
View article: Impact of Racial Differences in Hypoxia Distribution on the Measured Prevalence of Occult Hypoxemia by Pulse Oximeters
Impact of Racial Differences in Hypoxia Distribution on the Measured Prevalence of Occult Hypoxemia by Pulse Oximeters Open
BackgroundRacial differences in pulse oximeter accuracy increasingly have become recognized. However, previously published literature has not examined the extent to which underlying racial differences in levels of hypoxemia, such as those …
View article: Decreased Cardiac Autonomic Function is Associated with Higher Exacerbation Risk and Symptom Burden in Chronic Obstructive Pulmonary Disease
Decreased Cardiac Autonomic Function is Associated with Higher Exacerbation Risk and Symptom Burden in Chronic Obstructive Pulmonary Disease Open
Current measures of chronic obstructive pulmonary disease (COPD) severity, including lung function, do not fully explain symptom burden, and there is a need to identify predictors of exacerbation risk and morbidity. Autonomic dysfunction m…
View article: Airway and Systemic Prostaglandin E2 Association with COPD Symptoms and Macrophage Phenotype
Airway and Systemic Prostaglandin E2 Association with COPD Symptoms and Macrophage Phenotype Open
Elevated levels of sputum PGE-2, rather than systemic PGE-2, is associated with increased respiratory symptoms and history of exacerbation among individuals with COPD. Additional studies focused on mechanism of action are warranted.
View article: Dynamic Errors in Pulse Oximetry Preclude Use of Correction Factor
Dynamic Errors in Pulse Oximetry Preclude Use of Correction Factor Open
View article: Risk factors associated with chronic kidney disease progression: Long-term retrospective analysis from Qatar
Risk factors associated with chronic kidney disease progression: Long-term retrospective analysis from Qatar Open
Introduction: The risk factors influencing the natural course of chronic kidney disease (CKD) are complex and heterogeneous. Recognizing the factors associated with CKD progression can enable the identification of high-risk patients for mo…
View article: Urine and Plasma Markers of Platelet Activation and Respiratory Symptoms in COPD
Urine and Plasma Markers of Platelet Activation and Respiratory Symptoms in COPD Open
In stable moderate-severe COPD, elevated urinary11dTxB2, a metabolite of the platelet activation product thromboxane A2, was associated with worse respiratory symptoms, health status, and quality of life.
View article: Racial and Ethnic Discrepancy in Pulse Oximetry and Delayed Identification of Treatment Eligibility Among Patients With COVID-19
Racial and Ethnic Discrepancy in Pulse Oximetry and Delayed Identification of Treatment Eligibility Among Patients With COVID-19 Open
The results of this cohort study suggest that racial and ethnic biases in pulse oximetry accuracy were associated with greater occult hypoxemia in Asian, Black, and non-Black Hispanic patients with COVID-19, which was associated with signi…
View article: Ambient ozone effects on respiratory outcomes among smokers modified by neighborhood poverty: An analysis of SPIROMICS AIR
Ambient ozone effects on respiratory outcomes among smokers modified by neighborhood poverty: An analysis of SPIROMICS AIR Open
View article: Effective ultraviolet C light disinfection of respirators demonstrated in challenges with Geobacillus stearothermophilus spores and SARS-CoV-2 virus
Effective ultraviolet C light disinfection of respirators demonstrated in challenges with Geobacillus stearothermophilus spores and SARS-CoV-2 virus Open
View article: Patterns and Predictors of Air Cleaner Adherence Among Adults with COPD
Patterns and Predictors of Air Cleaner Adherence Among Adults with COPD Open
These findings suggest that cold weather season, use of gas for home heating, and lower annual income negatively impact adherence. Poor quality of life and worse disease control may also decrease adherence. Addressing factors associated wi…
View article: Cognitive Dysfunction, Psychiatric Distress, and Functional Decline After COVID-19
Cognitive Dysfunction, Psychiatric Distress, and Functional Decline After COVID-19 Open
View article: Role of Positron Emission Tomography with 2-Deoxy-2-[fluorine-18]fluoro-D-glucose Integrated with Computed Tomography in the Evaluation of Hepatic Metabolic Activity due to Steatosis in Lymphoma Patients and its Impact on Deauville Score
Role of Positron Emission Tomography with 2-Deoxy-2-[fluorine-18]fluoro-D-glucose Integrated with Computed Tomography in the Evaluation of Hepatic Metabolic Activity due to Steatosis in Lymphoma Patients and its Impact on Deauville Score Open
BACKGROUND: Liver uptake of 2-Deoxy-2-[fluorine-18]fluoro-D-glucose integrated (18F-FDG) is taken as the reference tissue in interpretation of Deauville score (DS), which is considered a response assessment. AIM: This study was conducted t…
View article: Metformin Use and Risk of Asthma Exacerbation Among Asthma Patients with Glycemic Dysfunction
Metformin Use and Risk of Asthma Exacerbation Among Asthma Patients with Glycemic Dysfunction Open
View article: Metformin: Experimental and Clinical Evidence for a Potential Role in Emphysema Treatment
Metformin: Experimental and Clinical Evidence for a Potential Role in Emphysema Treatment Open
Rationale: Cigarette smoke (CS) inhalation triggers oxidative stress and inflammation, leading to accelerated lung aging, apoptosis, and emphysema, as well as systemic pathologies. Metformin is beneficial for protecting against aging-relat…
View article: Emphysema Progression and Lung Function Decline Among Angiotensin Converting Enzyme Inhibitors and Angiotensin-Receptor Blockade Users in the COPDGene Cohort
Emphysema Progression and Lung Function Decline Among Angiotensin Converting Enzyme Inhibitors and Angiotensin-Receptor Blockade Users in the COPDGene Cohort Open