Alaa T. Alshareeda
YOU?
Author Swipe
View article: Improving the robustness and efficiency of cell sheet protocol for breast cancer induction in animal model: A Geltrex plus Gelatin approach
Improving the robustness and efficiency of cell sheet protocol for breast cancer induction in animal model: A Geltrex plus Gelatin approach Open
Background Breast cancer remains a global health challenge, necessitating improved preclinical models that better mimic the complexity of the disease. The cell sheet technique holds promise in creating three-dimensional tissue constructs r…
View article: Differential expression and regulation of ADAD1, DMRTC2, PRSS54, SYCE1, SYCP1, TEX101, TEX48, and TMPRSS12 gene profiles in colon cancer tissues and their in vitro response to epigenetic drugs
Differential expression and regulation of ADAD1, DMRTC2, PRSS54, SYCE1, SYCP1, TEX101, TEX48, and TMPRSS12 gene profiles in colon cancer tissues and their in vitro response to epigenetic drugs Open
Colon cancer (CC) is a significant cause of death worldwide, particularly in Saudi Arabia. To increase the accuracy of diagnosis and treatment, it is important to discover new specific biomarkers for CC. The main objectives of this researc…
View article: Hidden regulators: the emerging roles of lncRNAs in brain development and disease
Hidden regulators: the emerging roles of lncRNAs in brain development and disease Open
Long non-coding RNAs (lncRNAs) have emerged as critical players in brain development and disease. These non-coding transcripts, which once considered as “transcriptional junk,” are now known for their regulatory roles in gene expression. I…
View article: FTHL17, PRM2, CABYR, CPXCR1, ADAM29, and CABS1 are highly expressed in colon cancer patients and are regulated in vitro by epigenetic alterations
FTHL17, PRM2, CABYR, CPXCR1, ADAM29, and CABS1 are highly expressed in colon cancer patients and are regulated in vitro by epigenetic alterations Open
The findings of this study suggest that FTHL17, PRM2, CABYR, CPXCR1, ADAM29, and CABS1 are suitable candidate biomarkers of colon cancer and their expressions are regulated by hypomethylation and h…
View article: Homologous recombination mRNAs (RAD21, RAD50 and BARD1) have a potentially poor prognostic role in ERBB2-low bladder cancer patients
Homologous recombination mRNAs (RAD21, RAD50 and BARD1) have a potentially poor prognostic role in ERBB2-low bladder cancer patients Open
View article: Supplementary Figure S2 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer
Supplementary Figure S2 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer Open
Western blots and immunohistochemistry.
View article: Supplementary Figure S5 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer
Supplementary Figure S5 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer Open
BLM-Rad51 co-expression and survival in ER+ breast cancers.
View article: Supplementary Figure S4 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer
Supplementary Figure S4 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer Open
BLM-Rad51 co-expression and survival.
View article: Supplementary Tables from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer
Supplementary Tables from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer Open
Supplementary Tables S1-S9: Supplementary Table S1: Clinicopathological characteristics in the METABRIC cohort Supplementary Table S2: External validation cohorts (pooled n = 2413). Supplementary Table S3: Clinicopathological characteristi…
View article: Supplementary Figure S2 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer
Supplementary Figure S2 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer Open
Western blots and immunohistochemistry.
View article: Supplementary Figure S5 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer
Supplementary Figure S5 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer Open
BLM-Rad51 co-expression and survival in ER+ breast cancers.
View article: Data from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer
Data from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer Open
Bloom syndrome helicase (BLM) has key roles in homologous recombination repair, telomere maintenance, and DNA replication. Germ-line mutations in the BLM gene causes Bloom syndrome, a rare disorder characterized by premature aging a…
View article: Supplementary Figure S1 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer
Supplementary Figure S1 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer Open
BLM m RNA and breast cancer (external validation cohort).
View article: Supplementary Figure Legends from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer
Supplementary Figure Legends from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer Open
Supplementary Figure S1: BLM m RNA and breast cancer (external validation cohort). Supplementary Figure S2: Western blots and immunohistochemistry. Supplementary Figure S3: BLM protein expression and survival. Supplementary Figure S4: BLM-…
View article: Supplementary Figure S4 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer
Supplementary Figure S4 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer Open
BLM-Rad51 co-expression and survival.
View article: Data from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer
Data from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer Open
Bloom syndrome helicase (BLM) has key roles in homologous recombination repair, telomere maintenance, and DNA replication. Germ-line mutations in the BLM gene causes Bloom syndrome, a rare disorder characterized by premature aging a…
View article: Supplementary Tables from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer
Supplementary Tables from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer Open
Supplementary Tables S1-S9: Supplementary Table S1: Clinicopathological characteristics in the METABRIC cohort Supplementary Table S2: External validation cohorts (pooled n = 2413). Supplementary Table S3: Clinicopathological characteristi…
View article: Supplementary Figure S3 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer
Supplementary Figure S3 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer Open
BLM protein expression and survival.
View article: Supplementary Figure S3 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer
Supplementary Figure S3 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer Open
BLM protein expression and survival.
View article: Supplementary Figure S1 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer
Supplementary Figure S1 from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer Open
BLM m RNA and breast cancer (external validation cohort).
View article: Supplementary Figure Legends from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer
Supplementary Figure Legends from Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer Open
Supplementary Figure S1: BLM m RNA and breast cancer (external validation cohort). Supplementary Figure S2: Western blots and immunohistochemistry. Supplementary Figure S3: BLM protein expression and survival. Supplementary Figure S4: BLM-…
View article: Interaction between <scp>HER2</scp> and <scp>ATM</scp> predicts poor survival in bladder cancer patients
Interaction between <span>HER2</span> and <span>ATM</span> predicts poor survival in bladder cancer patients Open
Human Epidermal Growth Factor Receptor 2 (HER2) overexpression is considered one of the interesting prognostic biomarkers in bladder cancer. However, the mechanism of bladder cancer development in relation to HER2 status remains to be eluc…
View article: Nanotechnology: A revolutionary approach to prevent breast cancer recurrence
Nanotechnology: A revolutionary approach to prevent breast cancer recurrence Open
Breast cancer is the most prevalent malignancy in women worldwide and one of the deadliest after lung cancer. Currently, standard treatment approaches for breast cancers are surgery accompanied by chemotherapy or radiotherapy. Cancer local…
View article: Stem cells and the pursuit of youth, a tale of limitless possibilities and commercial fraud
Stem cells and the pursuit of youth, a tale of limitless possibilities and commercial fraud Open
This article examines the hype generated around the term "stem cell", and the capitalization of the stem cell craze by the cosmetic industry. It started by introducing product lines containing active ingredients derived from plant stem cel…
View article: Nanogenomics and Artificial Intelligence: A Dynamic Duo for the Fight Against Breast Cancer
Nanogenomics and Artificial Intelligence: A Dynamic Duo for the Fight Against Breast Cancer Open
Application software is utilized to aid in the diagnosis of breast cancer. Yet, recent advances in artificial intelligence (AI) are addressing challenges related to the detection, classification, and monitoring of different types of tumors…
View article: The Impact of Mastectomy on Self-Concept and Social Life: Decisional Conflicts for Breast Reconstruction
The Impact of Mastectomy on Self-Concept and Social Life: Decisional Conflicts for Breast Reconstruction Open
Background: Having a mastectomy affects a woman psychosocially, especially to adapt to the changes of her body. It is important to understand women's motivation for breast reconstruction surgery (BRS) to reconcile themselves with their own…
View article: Gender differences in response towards COVID 19-related content on social media
Gender differences in response towards COVID 19-related content on social media Open
View article: Preparing the Bone Tissue Regeneration Ground by Exosomes: From Diagnosis to Therapy
Preparing the Bone Tissue Regeneration Ground by Exosomes: From Diagnosis to Therapy Open
Bone tissue engineering employs acellular scaffolds or scaffolds, along with cells and growth factors, to provide the mechanical support needed, as well as serve as a delivery vehicle for bioactive molecules to the injury sites. As tissue …
View article: Cancer Stem Cell-Exosomes, Unexposed Player in Tumorigenicity
Cancer Stem Cell-Exosomes, Unexposed Player in Tumorigenicity Open
OPINION article Front. Pharmacol., 30 March 2020 | https://doi.org/10.3389/fphar.2020.00384
View article: Cancer of Unknown Primary Site: Real Entity or Misdiagnosed Disease?
Cancer of Unknown Primary Site: Real Entity or Misdiagnosed Disease? Open
Metastasis is a late event in the progression of any tumour. However, invasive cancers are occasionally detected in the form of metastatic lesions without a clearly detectable primary tumour. Cancer of unknown primary site (CUP) is defined…