Alan E. Rowan
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View article: Tuning collagen nonlinear mechanics with interpenetrating networks drives adaptive cellular phenotypes in three dimensions
Tuning collagen nonlinear mechanics with interpenetrating networks drives adaptive cellular phenotypes in three dimensions Open
In living tissues, collagen networks rarely exist alone because they are embedded within other biological matrices. When combined, collagen networks rigidify via synergistic mechanical interactions and stiffen only with higher mechanical l…
View article: The Potential of Sugarcane Waste-Derived Cellulose Fibres as Haemostatic Agents
The Potential of Sugarcane Waste-Derived Cellulose Fibres as Haemostatic Agents Open
Haemorrhage control during surgery and following traumatic injury remains a critical, life-saving challenge. Cellulose products are already employed in commercially available haemostatic dressings. This work explores sourcing cellulose fro…
View article: Tuning non-linear mechanics in collagen hydrogels modulates cellular morphotypes in three dimensions
Tuning non-linear mechanics in collagen hydrogels modulates cellular morphotypes in three dimensions Open
Collagen networks contribute to tissue architecture and modulate cellular responses in crowded three-dimensional environments. Therefore, it is the most widely used biological polymer in three-dimensional studies of cellular interactions w…
View article: Hyaluronic acid turnover controls the severity of cerebral cavernous malformations in bioengineered human micro-vessels
Hyaluronic acid turnover controls the severity of cerebral cavernous malformations in bioengineered human micro-vessels Open
Cerebral cavernous malformations (CCMs) are vascular lesions that predominantly form in blood vessels of the central nervous system upon loss of the CCM multimeric protein complex. The endothelial cells within CCM lesions are characterized…
View article: Controlling ligand density and viscoelasticity in synthetic biomimetic polyisocyanide hydrogels for studying cell behaviours: the key to truly biomimetic hydrogels
Controlling ligand density and viscoelasticity in synthetic biomimetic polyisocyanide hydrogels for studying cell behaviours: the key to truly biomimetic hydrogels Open
Integrin-binding peptide addition and density effects bundling and mechanical properties of polyisocyanide-based hydrogels influencing strain stiffening responsiveness, viscoelasticity, stiffness, matrix architecture and cellular behaviour…
View article: Materials Space‐Tectonics: Atomic‐level Compositional and Spatial Control Methodologies for Synthesis of Future Materials
Materials Space‐Tectonics: Atomic‐level Compositional and Spatial Control Methodologies for Synthesis of Future Materials Open
Reactions occurring at surfaces and interfaces necessitate the creation of well‐designed surface and interfacial structures. To achieve a combination of bulk material ( i.e ., framework) and void spaces, a meticulous process of “nano‐archi…
View article: Materials Space‐Tectonics: Atomic‐level Compositional and Spatial Control Methodologies for Synthesis of Future Materials
Materials Space‐Tectonics: Atomic‐level Compositional and Spatial Control Methodologies for Synthesis of Future Materials Open
Reactions occurring at surfaces and interfaces necessitate the creation of well‐designed surface and interfacial structures. To achieve a combination of bulk material ( i.e ., framework) and void spaces, a meticulous process of “nano‐archi…
View article: Hyaluronic acid turnover controls the severity of Cerebral Cavernous Malformations in bioengineered human micro-vessels
Hyaluronic acid turnover controls the severity of Cerebral Cavernous Malformations in bioengineered human micro-vessels Open
Cerebral Cavernous Malformations (CCMs) are vascular lesions that predominantly form in blood vessels of the central nervous system (CNS) upon loss of the CCM multimeric protein complex. The endothelial cells (ECs) within CCM lesions are c…
View article: N and S co-doped nanosheet-like porous carbon derived from sorghum biomass: mechanical nanoarchitecturing for upgraded potassium ion batteries
N and S co-doped nanosheet-like porous carbon derived from sorghum biomass: mechanical nanoarchitecturing for upgraded potassium ion batteries Open
Nanosheet-like sorghum biomass obtained by mild alkaline treatment and high-energy ball milling is heteroatom-doped with N and S during pyrolysis. The resulting N, S co-doped carbon shows a significantly improved K-ion storage as an anode …
View article: Evaluation of techniques used for visualisation of hydrogel morphology and determination of pore size distributions
Evaluation of techniques used for visualisation of hydrogel morphology and determination of pore size distributions Open
This study evaluated stimulated emission depletion (STED) microscopy, atomic force microscopy (AFM), and cryogenic scanning electron microscopy (Cryo-SEM), for visualising the morphology and obtaining pore size information of agarose hydro…
View article: Correction: Co, Fe and N co-doped 1D assembly of hollow carbon nanoboxes for high-performance supercapacitors
Correction: Co, Fe and N co-doped 1D assembly of hollow carbon nanoboxes for high-performance supercapacitors Open
Correction for ‘Co, Fe and N co-doped 1D assembly of hollow carbon nanoboxes for high-performance supercapacitors’ by Minjun Kim et al. , J. Mater. Chem. A , 2022, 10 , 24056–24063, https://doi.org/10.1039/D2TA06950D.
View article: Transcriptional comparison of testicular adrenal rest tumors with fetal and adult tissues
Transcriptional comparison of testicular adrenal rest tumors with fetal and adult tissues Open
Background Testicular adrenal rest tumors (TART) are a common complication of unknown cellular origin in patients with congenital adrenal hyperplasia (CAH). These benign tumors have both adrenal and testicular characteristics and are hypot…
View article: Snake venom-defined fibrin architecture dictates fibroblast survival and differentiation
Snake venom-defined fibrin architecture dictates fibroblast survival and differentiation Open
Fibrin is commonly used as a natural hydrogel for three-dimensional (3D) cell culture but is poorly defined. We demonstrate a novel snake venom-controlled fibrin system with tunable architectural and mechanical properties. Employing the sn…
View article: Snake Venom Hydrogels as a Rapid Hemostatic Agent for Uncontrolled Bleeding
Snake Venom Hydrogels as a Rapid Hemostatic Agent for Uncontrolled Bleeding Open
Uncontrolled bleeding from traumatic injury remains the leading cause of preventable death with loss of balance between blood clotting (coagulation) and blood clot breakdown (fibrinolysis). A major limitation of existing hemostatic agents …
View article: The Mechanosensory Role of Osteocytes and Implications for Bone Health and Disease States
The Mechanosensory Role of Osteocytes and Implications for Bone Health and Disease States Open
Bone homeostasis is a dynamic equilibrium between bone-forming osteoblasts and bone-resorbing osteoclasts. This process is primarily controlled by the most abundant and mechanosensitive bone cells, osteocytes, that reside individually, wit…
View article: Magnetic anisotropy of individually addressed spin states
Magnetic anisotropy of individually addressed spin states Open
Controlling magnetic anisotropy is a key requirement for the fundamental understanding of molecular magnetism and is a prerequisite for numerous applications in magnetic storage, spintronics, and all-spin logic devices. In order to address…
View article: The magnetic anisotropy of individually addressed spin states
The magnetic anisotropy of individually addressed spin states Open
Controlling magnetic anisotropy is a key requirement for the fundamental understanding of molecular magnetism and is a prerequisite for numerous applications in magnetic storage, spintronics, and all-spin logic devices. In order to address…
View article: Heterodyne Brillouin microscopy for biomechanical imaging
Heterodyne Brillouin microscopy for biomechanical imaging Open
Microscopic variations in material stiffness play a vital role in cellular scale biomechanics, but are difficult to measure in a natural 3D environment. Brillouin microscopy is a promising technology for such applications, providing non-co…
View article: CCDC 2086937: Experimental Crystal Structure Determination
CCDC 2086937: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2086941: Experimental Crystal Structure Determination
CCDC 2086941: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2086940: Experimental Crystal Structure Determination
CCDC 2086940: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Synthesis and Magnetic Properties of Two‐Step‐Coordination Schiff Base Clusters
Synthesis and Magnetic Properties of Two‐Step‐Coordination Schiff Base Clusters Open
A new family of paramagnetic coordination compounds based on a diimine‐pyridine pincer ligand has been prepared, using a two‐step synthetic approach. The sequential introduction of identical or different transition metals (Co, Mn, Ni, Zn) …
View article: Adsorchromism: Molecular Nanoarchitectonics at 2D Nanosheets—Old Chemistry for Advanced Chromism
Adsorchromism: Molecular Nanoarchitectonics at 2D Nanosheets—Old Chemistry for Advanced Chromism Open
Chromism induced by changes in the electronic states of dye molecules due to surface adsorption is termed “adsorchromism” in this article. These changes of molecular electronic states are induced by protonation, aggregation, intramolecular…
View article: In Search of Excellence: Convex versus Concave Noble Metal Nanostructures for Electrocatalytic Applications
In Search of Excellence: Convex versus Concave Noble Metal Nanostructures for Electrocatalytic Applications Open
Controlling the shape of noble metal nanoparticles is a challenging but important task in electrocatalysis. Apart from hollow and nanocage structures, concave noble metal nanoparticles are considered a new class of unconventional electroca…