Alan F. Murray
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View article: pH-Activated Dissolvable Polymeric Coatings to Reduce Biofouling on Electrochemical Sensors
pH-Activated Dissolvable Polymeric Coatings to Reduce Biofouling on Electrochemical Sensors Open
Implantable electrochemical sensors that enable the real-time detection of significant biomarkers offer huge potential for the enhancement and personalisation of therapies; however, biofouling is a key challenge encountered by any implanta…
View article: In vivo application of an implantable tri-anchored methylene blue-based electrochemical pH sensor
In vivo application of an implantable tri-anchored methylene blue-based electrochemical pH sensor Open
View article: Adhesion and Growth of Neuralized Mouse Embryonic Stem Cells on Parylene-C/SiO2 Substrates
Adhesion and Growth of Neuralized Mouse Embryonic Stem Cells on Parylene-C/SiO2 Substrates Open
Neuronal patterning on microfabricated architectures has developed rapidly over the past few years, together with the emergence of soft biocompatible materials and tissue engineering scaffolds. Previously, we introduced a patterning techni…
View article: Predictive and Diagnostic Biomarkers of Anastomotic Leakage: A Precision Medicine Approach for Colorectal Cancer Patients
Predictive and Diagnostic Biomarkers of Anastomotic Leakage: A Precision Medicine Approach for Colorectal Cancer Patients Open
Development of an anastomotic leak (AL) following intestinal surgery for the treatment of colorectal cancers is a life-threatening complication. Failure of the anastomosis to heal correctly can lead to contamination of the abdomen with int…
View article: Real-time measurement of tumour hypoxia using an implantable microfabricated oxygen sensor
Real-time measurement of tumour hypoxia using an implantable microfabricated oxygen sensor Open
View article: The impact of tumour pH on cancer progression: strategies for clinical intervention
The impact of tumour pH on cancer progression: strategies for clinical intervention Open
Dysregulation of cellular pH is frequent in solid tumours and provides potential opportunities for therapeutic intervention. The acidic microenvironment within a tumour can promote migration, invasion and metastasis of cancer cells through…
View article: Miniaturisation of a peptide-based electrochemical protease activity sensor using platinum microelectrodes
Miniaturisation of a peptide-based electrochemical protease activity sensor using platinum microelectrodes Open
A miniaturised sensor displayed efficient analytical performance with differences in kinetics from the macroelectrodes, attributed to the structural differences in probe accessibility.
View article: In vivo validation of a miniaturized electrochemical oxygen sensor for measuring intestinal oxygen tension
In vivo validation of a miniaturized electrochemical oxygen sensor for measuring intestinal oxygen tension Open
Recent advances in the fields of electronics and microfabrication techniques have led to the development of implantable medical devices for use within the field of precision medicine. Monitoring visceral surface tissue O 2 tension ([Formul…
View article: Dataset for "Real-time measurement of tumour hypoxia using an implantable microfabricated oxygen sensor"
Dataset for "Real-time measurement of tumour hypoxia using an implantable microfabricated oxygen sensor" Open
Dataset for "Real-time measurement of tumour hypoxia using an implantable microfabricated oxygen sensor" by Marland et al. (2020) https://doi.org/10.1016/j.sbsr.2020.100375. # Change to title # The original title of this dataset was: 'Data…
View article: Data associated with manuscript: Miniaturisation of a peptide-based electrochemical protease activity sensor using platinum microelectrodes
Data associated with manuscript: Miniaturisation of a peptide-based electrochemical protease activity sensor using platinum microelectrodes Open
Data associated with the manuscript: "Miniaturisation of a peptide-based electrochemical protease activity sensor using platinum microelectrodes". Robust and sensitive miniaturised peptide-based electrochemical biosensor for protease activ…
View article: Electrochemical sensing of human neutrophil elastase and polymorphonuclear neutrophil activity
Electrochemical sensing of human neutrophil elastase and polymorphonuclear neutrophil activity Open
View article: A tripod anchor offers improved robustness of peptide-based electrochemical biosensors
A tripod anchor offers improved robustness of peptide-based electrochemical biosensors Open
View article: Horizon scanning implanted biosensors in personalising breast cancer management: <scp>First</scp> pilot study of breast cancer patients views
Horizon scanning implanted biosensors in personalising breast cancer management: <span>First</span> pilot study of breast cancer patients views Open
Aims This study aimed to explore breast cancer patients' understanding and acceptability of implanted biosensors (BS) within the primary tumour to personalise adjuvant radiotherapy, and to determine optimal design and number of BS, and eva…
View article: Data associated with manuscript: A tripod anchor offers improved robustness of peptide-based electrochemical biosensors
Data associated with manuscript: A tripod anchor offers improved robustness of peptide-based electrochemical biosensors Open
Data associated to manuscript. Includes set of tables containing the data used for obtaining figures and results.
View article: Electrodrugs: an electrochemical prodrug activation strategy
Electrodrugs: an electrochemical prodrug activation strategy Open
Controlled activation of a Pt(iv) prodrug into its active Pt(ii) form within a cellular context, using an electrochemical activation strategy.
View article: Data associated with manuscript: Electrochemical sensing of human neutrophil elastase and polymorphonuclear neutrophil activity
Data associated with manuscript: Electrochemical sensing of human neutrophil elastase and polymorphonuclear neutrophil activity Open
Data associated with the manuscript. "Electrochemical sensing of human neutrophil elastase and polymorphonuclear neutrophil activity". Design and evaluation of a peptide-based electrochemical biosensor for HNE activity detection. The analy…
View article: Effect of spacer length on the performance of peptide-based electrochemical biosensors for protease detection
Effect of spacer length on the performance of peptide-based electrochemical biosensors for protease detection Open
View article: Test structures for optimizing polymer electrolyte performance in a microfabricated electrochemical oxygen sensor
Test structures for optimizing polymer electrolyte performance in a microfabricated electrochemical oxygen sensor Open
Test structures were produced for optimizing the design and fabrication of a patterned solid polymer electrolyte in an electrochemical oxygen sensor. Measurements showed that choice of photoresist developer and the underlying insulator mat…
View article: Data associated with manuscript: Effect of spacer length on the performance of peptide-based electrochemical biosensors for protease detection
Data associated with manuscript: Effect of spacer length on the performance of peptide-based electrochemical biosensors for protease detection Open
The design of peptide-based electrochemical biosensors involves selecting a suitable spacer, connecting the peptide sequence with the anchor moiety. The effect of varying the length of such a spacer has been evaluated for an electrochemica…
View article: Methylene blue not ferrocene: Optimal reporters for electrochemical detection of protease activity
Methylene blue not ferrocene: Optimal reporters for electrochemical detection of protease activity Open
View article: Towards a ‘siliconeural computer’: technological successes and challenges
Towards a ‘siliconeural computer’: technological successes and challenges Open
Electronic signals govern the function of both nervous systems and computers, albeit in different ways. As such, hybridizing both systems to create an iono-electric brain–computer interface is a realistic goal; and one that promises exciti…
View article: Data associated with manuscript: Methylene blue not ferrocene: optimal reporters for electrochemical detection of protease activity
Data associated with manuscript: Methylene blue not ferrocene: optimal reporters for electrochemical detection of protease activity Open
Optimisation and evaluation of an electrochemical biosensor for protease activity employing self-assembled monolayers. A platform for detecting proteases in a clinically-relevant range is reported.