Alan F. Hofmann
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View article: Guts and Gall: Bile Acids in Regulation of Intestinal Epithelial Function in Health and Disease
Guts and Gall: Bile Acids in Regulation of Intestinal Epithelial Function in Health and Disease Open
Epithelial cells line the entire surface of the gastrointestinal tract and its accessory organs where they primarily function in transporting digestive enzymes, nutrients, electrolytes, and fluid to and from the luminal contents. At the sa…
View article: Absorption of Unconjugated Bile Acids from the Perfused Jejunum of the Anesthetized Rat: Structure–Activity Relationships and Rate‐Limiting Steps
Absorption of Unconjugated Bile Acids from the Perfused Jejunum of the Anesthetized Rat: Structure–Activity Relationships and Rate‐Limiting Steps Open
CA cholic acid CDCA chenodeoxycholic acid CDC
View article: Hepatobiliary Secretion Kinetics of Conjugated Bile Acids Measured in Pigs by <sup>11</sup> C-Cholylsarcosine PET
Hepatobiliary Secretion Kinetics of Conjugated Bile Acids Measured in Pigs by <sup>11</sup> C-Cholylsarcosine PET Open
The in vivo kinetics of hepatobiliary secretion of conjugated bile acids can now be determined by dynamic (11)C-CSar PET.
View article: Chemical Synthesis of Uncommon Natural Bile Acids: The 9α-Hydroxy Derivatives of Chenodeoxycholic and Lithocholic Acids
Chemical Synthesis of Uncommon Natural Bile Acids: The 9α-Hydroxy Derivatives of Chenodeoxycholic and Lithocholic Acids Open
The chemical synthesis of the 9α-hydroxy derivatives of chenodeoxycholic and lithocholic acids is reported. For initiating the synthesis of the 9α-hydroxy derivative of chenodeoxycholic acid, cholic acid was used; for the synthesis of the …