2019-01-01
A principled framework for phenotyping postpartum hemorrhage across multiple levels of severity.
2019-01-01 • Matthew Oberhardt, Alexander M. Friedman, Rimma Perotte, Jean‐Ju Sheen, Alan Kessler, David K. Vawdrey, Robert A. Green, Mary E. D’Alton, Dena Goffman
Maternal morbidity and mortality have gained major attention recently, spurred on by rising domestic rates even as maternal mortality decreases in Europe. A major driver of morbidity and mortality among delivering women is postpartum hemorrhage (PPH). PPH is currently phenotyped using the subjective measure of 'Estimated blood loss' (EBL), which has been shown to be unreliable for tracking quality. Here we present a framework for phenotyping PPH into multiple severity levels, using a combination of data-driven tec…