Alba Lucía Cómbita
YOU?
Author Swipe
View article: Data from Reduction in Vaccine HPV Type Infections in a Young Women Group (18–25 Years) Five Years after HPV Vaccine Introduction in Colombia
Data from Reduction in Vaccine HPV Type Infections in a Young Women Group (18–25 Years) Five Years after HPV Vaccine Introduction in Colombia Open
In Colombia, the human papillomavirus (HPV) vaccine was launched in 2012 in the context of a school-based national vaccination program targeting girls ages 9 to 14 and offering catch-up vaccination for girls ages 14 to 17. In this study, w…
View article: Figure 5 from Reduction in Vaccine HPV Type Infections in a Young Women Group (18–25 Years) Five Years after HPV Vaccine Introduction in Colombia
Figure 5 from Reduction in Vaccine HPV Type Infections in a Young Women Group (18–25 Years) Five Years after HPV Vaccine Introduction in Colombia Open
HPV prevalence by Pap smear result. Comparison of cytological abnormalities between unvaccinated and vaccinates women ages 18 to 25 years (A) prevalence of HPV types in ASC-US and (B) L-SIL. Adjusted by using a propensity sco…
View article: Figure 3 from Reduction in Vaccine HPV Type Infections in a Young Women Group (18–25 Years) Five Years after HPV Vaccine Introduction in Colombia
Figure 3 from Reduction in Vaccine HPV Type Infections in a Young Women Group (18–25 Years) Five Years after HPV Vaccine Introduction in Colombia Open
Prevalence of HPV vaccine types in the study population. Comparison between unvaccinated and vaccinates women ages 18 to 25 years according to doses (A) and to sexual debut (B).
View article: Table 1 from Reduction in Vaccine HPV Type Infections in a Young Women Group (18–25 Years) Five Years after HPV Vaccine Introduction in Colombia
Table 1 from Reduction in Vaccine HPV Type Infections in a Young Women Group (18–25 Years) Five Years after HPV Vaccine Introduction in Colombia Open
Characteristic of the study population. Comparison between vaccinated and unvaccinated women ages 18 to 25 years by sociodemographic and sexual behavior characteristics.
View article: Figure 4 from Reduction in Vaccine HPV Type Infections in a Young Women Group (18–25 Years) Five Years after HPV Vaccine Introduction in Colombia
Figure 4 from Reduction in Vaccine HPV Type Infections in a Young Women Group (18–25 Years) Five Years after HPV Vaccine Introduction in Colombia Open
Vaccine effectiveness (VE) in vaccinated women aged 18–25 years: to different groups of HPV types (A) and to HPV16/18 according to sexual debut and number of doses (B). VEaAdjusted by using a propensity score analy…
View article: Figure 1 from Reduction in Vaccine HPV Type Infections in a Young Women Group (18–25 Years) Five Years after HPV Vaccine Introduction in Colombia
Figure 1 from Reduction in Vaccine HPV Type Infections in a Young Women Group (18–25 Years) Five Years after HPV Vaccine Introduction in Colombia Open
Prevalence of HPV types in the study population. Comparison between unvaccinated and vaccinates women ages 18 to 25 years. Adjusted by using a propensity score analysis.
View article: Figure 2 from Reduction in Vaccine HPV Type Infections in a Young Women Group (18–25 Years) Five Years after HPV Vaccine Introduction in Colombia
Figure 2 from Reduction in Vaccine HPV Type Infections in a Young Women Group (18–25 Years) Five Years after HPV Vaccine Introduction in Colombia Open
Prevalence of HR-HPV types in the study population. Comparison between unvaccinated and vaccinates women ages 18 to 25 years. Adjusted by using a propensity score analysis.
View article: Molecular determinants of neoadjuvant chemotherapy resistance in breast cancer: An analysis of gene expression and tumor microenvironment
Molecular determinants of neoadjuvant chemotherapy resistance in breast cancer: An analysis of gene expression and tumor microenvironment Open
Neoadjuvant chemotherapy (NAC) is a critical component of breast cancer treatment, but the molecular mechanisms underlying resistance remain poorly understood. This study aimed to identify transcriptomic changes associated with NAC resista…
View article: Diffuse gliomas: insights into clinical and histopathological features and survival rates from two centers in a middle-income country
Diffuse gliomas: insights into clinical and histopathological features and survival rates from two centers in a middle-income country Open
Introduction Gliomas are believed to arise from neuroglial stem cells and are histologically classified based on morphological similarities to normal neuroglial cells. This study aims to describe the clinical, histopathological, and demogr…
View article: Correction: Transcriptional landscape of pleural mesothelioma patients in relation to NF2 gene mutational status
Correction: Transcriptional landscape of pleural mesothelioma patients in relation to NF2 gene mutational status Open
View article: Integrative Transcriptomic Meta-Analysis Reveals Risk Signatures and Immune Infiltration Patterns in High-Grade Serous Ovarian Cancer
Integrative Transcriptomic Meta-Analysis Reveals Risk Signatures and Immune Infiltration Patterns in High-Grade Serous Ovarian Cancer Open
Background: High-grade serous ovarian cancer (HGSOC) is a highly aggressive malignancy with poor prognosis due to late-stage diagnosis and limited treatments. Identifying differentially expressed genes (DEGs), and immune cell infiltration …
View article: Transcriptional landscape of pleural mesothelioma patients in relation to NF2 gene mutational status
Transcriptional landscape of pleural mesothelioma patients in relation to NF2 gene mutational status Open
Background Pleural mesothelioma (PM) is an aggressive cancer with poor prognosis, often driven by asbestos exposure. Mutations in the NF2 gene, a key regulator of the Hippo signaling pathway, are frequently observed in PM. However, their i…
View article: Development and Validation of an Extracellular Matrix Gene Expression Signature for Prognostic Prediction in Patients with Uveal Melanoma
Development and Validation of an Extracellular Matrix Gene Expression Signature for Prognostic Prediction in Patients with Uveal Melanoma Open
Uveal melanoma (UVM) is an aggressive cancer with a poor prognosis, particularly in metastatic cases. This study aimed to develop and validate a novel extracellular matrix (ECM) gene expression signature to predict prognosis and stratify p…
View article: Current Applications of Single-Cell RNA Sequencing in Glioblastoma: A Scoping Review
Current Applications of Single-Cell RNA Sequencing in Glioblastoma: A Scoping Review Open
Background and Objective: The discovery of novel molecular biomarkers via next-generation sequencing technologies has revolutionized how glioblastomas (GBMs) are classified nowadays. This has resulted in more precise diagnostic, prognostic…
View article: ID1 and ID3 functions in the modulation of the tumour immune microenvironment in adult patients with B-cell acute lymphoblastic leukaemia
ID1 and ID3 functions in the modulation of the tumour immune microenvironment in adult patients with B-cell acute lymphoblastic leukaemia Open
Introduction B-cell acute lymphoblastic leukemia (B-ALL) in adults often presents a poor prognosis. ID1 and ID3 genes have been identified as predictors of poor response in Colombian adult B-ALL patients, contributing to cancer development…
View article: MIR4435-2HG as a possible novel predictive biomarker of chemotherapy response and death in pediatric B-cell ALL
MIR4435-2HG as a possible novel predictive biomarker of chemotherapy response and death in pediatric B-cell ALL Open
Introduction: Although B-cell acute lymphoblastic leukemia (B-cell ALL) survival rates have improved in recent years, Hispanic children continue to have poorer survival rates. There are few tools available to identify at the time of diagno…
View article: Genetic ancestry and radical prostatectomy findings in Hispanic/Latino patients
Genetic ancestry and radical prostatectomy findings in Hispanic/Latino patients Open
Background African ancestry is a known factor associated with the presentation and aggressiveness of prostate cancer (PC). Hispanic/Latino populations exhibit varying degrees of genetic admixture across Latin American countries, leading to…
View article: Gliomas difusos en áreas elocuentes: avances diagnósticos y terapéuticos
Gliomas difusos en áreas elocuentes: avances diagnósticos y terapéuticos Open
Objective: to present the diagnostic, molecular, radiological, and therapeutic advances, to address diffuse gliomas, made at Fundación Universitaria de Ciencias de la Salud (FUCS), Bogotá D.C., Colombia, in the last 5 years (2018-2023). Ma…
View article: Contribution of the TIME in BCP-ALL: the basis for novel approaches therapeutics
Contribution of the TIME in BCP-ALL: the basis for novel approaches therapeutics Open
The bone marrow (BM) niche is a microenvironment where both immune and non-immune cells functionally interact with hematopoietic stem cells (HSC) and more differentiated progenitors, contributing to the regulation of hematopoiesis. It is r…
View article: The potential of miRNA-based approaches in glioblastoma: An update in current advances and future perspectives
The potential of miRNA-based approaches in glioblastoma: An update in current advances and future perspectives Open
Glioblastoma (GBM) is the most common malignant central nervous system tumor. The emerging field of epigenetics stands out as particularly promising. Notably, the discovery of micro RNAs (miRNAs) has paved the way for advancements in diagn…
View article: MIR4435-2HG as a Novel Predictive Biomarker of Chemotherapy Response and Death in Pediatric B-cell All
MIR4435-2HG as a Novel Predictive Biomarker of Chemotherapy Response and Death in Pediatric B-cell All Open
Background Although B-cell acute lymphoblastic leukemia (B-cell ALL) survival rates have improved in recent years, Hispanic children continue to have poorer survival rates. There are few tools available to identify from the time of diagnos…
View article: Validation of an Ultraviolet Light Response Gene Signature for Predicting Prognosis in Patients with Uveal Melanoma
Validation of an Ultraviolet Light Response Gene Signature for Predicting Prognosis in Patients with Uveal Melanoma Open
Uveal melanoma (UVM) is a highly aggressive ocular cancer with limited therapeutic options and poor prognosis particularly for patients with liver metastasis. As such, the identification of new prognostic biomarkers is critical for develop…
View article: Understanding the molecular profiling of diffuse gliomas classification: A brief overview
Understanding the molecular profiling of diffuse gliomas classification: A brief overview Open
Background: Gliomas represent almost 30% of all primary brain tumors and account for 80% of malignant primary ones. In the last two decades, significant progress has been made in understanding gliomas’ molecular origin and development. The…
View article: MIR4435-2HG as a Novel Predictive Biomarker of Chemotherapy Response and Death in Pediatric B-Cell All
MIR4435-2HG as a Novel Predictive Biomarker of Chemotherapy Response and Death in Pediatric B-Cell All Open
Although B-cell acute lymphoblastic leukemia (B-cell ALL) survival rates have improved in recent years, Hispanic children continue to have poorer survival rates. Our aim was to identify biomarkers of treatment response, which may also pred…
View article: Data from Detection and Genotyping of HPV DNA in a Group of Unvaccinated Young Women from Colombia: Baseline Measures Prior to Future Monitoring Program
Data from Detection and Genotyping of HPV DNA in a Group of Unvaccinated Young Women from Colombia: Baseline Measures Prior to Future Monitoring Program Open
In 2012, Colombia launched human papillomavirus (HPV) vaccination program for girls ages 9 to 12, and in 2013, the target age was expanded to 9 to 17 years. Monitoring the changes of HPV infection prevalence among young women has been prop…
View article: Table 2S. from Comparison between Urine and Cervical Samples for HPV DNA Detection and Typing in Young Women in Colombia
Table 2S. from Comparison between Urine and Cervical Samples for HPV DNA Detection and Typing in Young Women in Colombia Open
Prevalence of HPV infection in cervical and urine samples according to cytological results in young women aged 18-25 years from Soacha and Manizales, Colombia.
View article: Figure 2S. from Comparison between Urine and Cervical Samples for HPV DNA Detection and Typing in Young Women in Colombia
Figure 2S. from Comparison between Urine and Cervical Samples for HPV DNA Detection and Typing in Young Women in Colombia Open
Agreement among cervix and urine samples for the detection of HR/pHR HPV types different from HPV 16 and 18.
View article: Data from Detection and Genotyping of HPV DNA in a Group of Unvaccinated Young Women from Colombia: Baseline Measures Prior to Future Monitoring Program
Data from Detection and Genotyping of HPV DNA in a Group of Unvaccinated Young Women from Colombia: Baseline Measures Prior to Future Monitoring Program Open
In 2012, Colombia launched human papillomavirus (HPV) vaccination program for girls ages 9 to 12, and in 2013, the target age was expanded to 9 to 17 years. Monitoring the changes of HPV infection prevalence among young women has been prop…
View article: Figure 1S. from Comparison between Urine and Cervical Samples for HPV DNA Detection and Typing in Young Women in Colombia
Figure 1S. from Comparison between Urine and Cervical Samples for HPV DNA Detection and Typing in Young Women in Colombia Open
Number of HPV types in cervical and urine samples.
View article: Table 1S. from Comparison between Urine and Cervical Samples for HPV DNA Detection and Typing in Young Women in Colombia
Table 1S. from Comparison between Urine and Cervical Samples for HPV DNA Detection and Typing in Young Women in Colombia Open
Sensitivity and specificity of urine HPV DNA test for high-risk (HR)-HPV and probable/possible high-risk (pHR)-HPV types different from HPV 16 and 18. (Results of cervical samples used as gold standard).