Albert Abhishek
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View article: Biochemical and molecular anticancer approaches for Boerhaavia diffusa root extracts in oral cancer
Biochemical and molecular anticancer approaches for Boerhaavia diffusa root extracts in oral cancer Open
Background: Boerhaavia diffusa is a medicinal herb with anti-inflammatory, antiproliferative, anticancer, and immunomodulatory properties, found across India. Aim and Objectives: The present study is designed to investigate the therapeutic…
View article: Effect of cadmium on essential metals and their impact on lipid metabolism in Saccharomyces cerevisiae
Effect of cadmium on essential metals and their impact on lipid metabolism in Saccharomyces cerevisiae Open
View article: Renoprotective effect of tectorigenin glycosides isolated from <i>Iris spuria</i> L. (Zeal) against hyperoxaluria and hyperglycemia in NRK-49Fcells
Renoprotective effect of tectorigenin glycosides isolated from <i>Iris spuria</i> L. (Zeal) against hyperoxaluria and hyperglycemia in NRK-49Fcells Open
Oxidative stress has been identified as an underlying factor in the development of insulin resistance, β-cell dysfunction, impaired glucose tolerance and type 2 diabetes mellitus and it also play major role in kidney stone formation. The p…
View article: Combination of ramipril and rutin alleviate alloxan induced diabetic nephropathy targeting multiple stress pathways in vivo
Combination of ramipril and rutin alleviate alloxan induced diabetic nephropathy targeting multiple stress pathways in vivo Open
Diabetic nephropathy (DN) is considered as one of the major microvascular complications of diabetes mellitus (DM) which leads to end stage renal disease (ESRD). Even though existing therapeutic options are effective in decreasing albuminur…
View article: Oral administration of oxalate-enriched spinach extract as an improved methodology for the induction of dietary hyperoxaluric nephrocalcinosis in experimental rats
Oral administration of oxalate-enriched spinach extract as an improved methodology for the induction of dietary hyperoxaluric nephrocalcinosis in experimental rats Open
Experimental induction of hyperoxaluria by ethylene glycol (EG) administration is disapproved as it causes metabolic acidosis while the oral administration of chemically synthesized potassium oxalate (KOx) diet does not mimic our natural s…
View article: Gut microbial degradation of organophosphate insecticides-induces glucose intolerance via gluconeogenesis
Gut microbial degradation of organophosphate insecticides-induces glucose intolerance via gluconeogenesis Open
Collectively, our results implicate gluconeogenesis as the key mechanism behind organophosphate-induced hyperglycemia, mediated by the organophosphate-degrading potential of gut microbiota. This study reveals the gut microbiome-mediated di…
View article: Expression of heterologous oxalate decarboxylase in HEK293 cells confers protection against oxalate induced oxidative stress as a therapeutic approach for calcium oxalate stone disease
Expression of heterologous oxalate decarboxylase in HEK293 cells confers protection against oxalate induced oxidative stress as a therapeutic approach for calcium oxalate stone disease Open
Oxalates stimulate alterations in renal epithelial cells and thereby induce calcium oxalate (CaOx) stone formation. Bacillus subtilis YvrK gene encodes for oxalate decarboxylase (OxdC) which degrades oxalate to formate and CO2. …