Albert Lai
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View article: IMG-43. Non-Invasive Prediction of Malignant Transformation in Grade 2 IDH-Mutant Gliomas Using Radiomics and Machine Learning
IMG-43. Non-Invasive Prediction of Malignant Transformation in Grade 2 IDH-Mutant Gliomas Using Radiomics and Machine Learning Open
Grade 2 IDH mutant gliomas are known to undergo malignant transformation (MT). Early prediction of this transformation remains a significant clinical challenge. Radiomics, the extraction of high-dimensional imaging features, has emerged as…
View article: IMG-68. Corticosteroid-induced contrast-enhancing volume shrinkage and apparent diffusion coefficient reduction in glioblastoma MRI
IMG-68. Corticosteroid-induced contrast-enhancing volume shrinkage and apparent diffusion coefficient reduction in glioblastoma MRI Open
BACKGROUND Corticosteroids, which are commonly used in the clinical management of glioblastoma, are known to impact the radiographic interpretation of glioblastoma. In particular, corticosteroids can induce an apparent reduction in contras…
View article: PATH-51. Identification of molecular markers predicting malignant transformation in low grade gliomas
PATH-51. Identification of molecular markers predicting malignant transformation in low grade gliomas Open
Low-grade gliomas generally have an indolent course and good prognosis after maximal safe resection; however, progression to high-grade gliomas via malignant transformation is a poorly understood process. In order to further elucidate the …
View article: Wharton’s Jelly Allografts for Intra-Articular Cartilage Degeneration in the Ankle
Wharton’s Jelly Allografts for Intra-Articular Cartilage Degeneration in the Ankle Open
Introduction: Despite its lower prevalence, ankle osteoarthritis is equally debilitating as the more commonly known types of osteoarthritis. The high complication rate for surgical intervention necessitates the need for more efficacious, c…
View article: Advanced imaging characterization of post-chemoradiation glioblastoma stratified by diffusion MRI phenotypes known to predict favorable anti-VEGF response
Advanced imaging characterization of post-chemoradiation glioblastoma stratified by diffusion MRI phenotypes known to predict favorable anti-VEGF response Open
Purpose Recurrent glioblastomas showing a survival benefit from anti-VEGF agents are known to exhibit a distinct diffusion MRI phenotype. We aim to characterize advanced imaging features of this glioblastoma subset. Methods MRI scans from …
View article: Supplementary Figure 1 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Figure 1 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Fig S1A-D
View article: Supplementary Figure 4 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Figure 4 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Fig S4 A-C
View article: Supplementary Figure 6 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Figure 6 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Fig S6 A-F
View article: Supplementary Data 2 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Data 2 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
hERV raw counts and FPKM values
View article: Supplementary Figure 5 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Figure 5 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Fig S5 A-F
View article: Supplementary Figure 3 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Figure 3 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Fig S3 A-C
View article: Supplementary Data 1 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Data 1 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Isoplexis fluorescence values per cytokine per cell
View article: Supplementary Figure 2 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Figure 2 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Fig S2 A-C
View article: A comparative study of preclinical and clinical molecular imaging response to EGFR inhibition using osimertinib in glioblastoma
A comparative study of preclinical and clinical molecular imaging response to EGFR inhibition using osimertinib in glioblastoma Open
Background To demonstrate the potential value of 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) as a rapid, non-invasive metabolic imaging surrogate for pharmacological modulation of EGFR signaling in EGFR-driven GBM, we…
View article: Publisher Correction: Valproic acid targets IDH1 mutants through alteration of lipid metabolism
Publisher Correction: Valproic acid targets IDH1 mutants through alteration of lipid metabolism Open
View article: Diffusion MRI is superior to quantitative T2-FLAIR mismatch in predicting molecular subtypes of human non-enhancing gliomas
Diffusion MRI is superior to quantitative T2-FLAIR mismatch in predicting molecular subtypes of human non-enhancing gliomas Open
Purpose This study compared the classification performance of normalized apparent diffusion coefficient (nADC) with percentage T2-FLAIR mismatch-volume (%T2FM-volume) for differentiating between IDH-mutant astrocytoma (IDHm-A) and other gl…
View article: Supplementary Figure 3 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Figure 3 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Fig S3 A-C
View article: Supplementary Figure 4 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Figure 4 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Fig S4 A-C
View article: Supplementary Figure 6 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Figure 6 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Fig S6 A-F
View article: Supplementary Figure 5 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Figure 5 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Fig S5 A-F
View article: Supplementary Data 1 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Data 1 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Isoplexis fluorescence values per cytokine per cell
View article: Supplementary Figure 4 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Figure 4 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Fig S4 A-C
View article: Supplementary Data 2 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Data 2 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
hERV raw counts and FPKM values
View article: Supplementary Figure 1 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Figure 1 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Fig S1A-D
View article: Supplementary Figure 1 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Figure 1 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Fig S1A-D
View article: Supplementary Figure 6 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Figure 6 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Fig S6 A-F
View article: Supplementary Data 1 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Data 1 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Isoplexis fluorescence values per cytokine per cell
View article: Supplementary Figure 3 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Figure 3 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Fig S3 A-C
View article: Supplementary Figure 2 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Supplementary Figure 2 from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Fig S2 A-C
View article: Data from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
Data from Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma Open
Glioblastoma (GBM) is the most common malignant primary brain tumor and remains incurable. Previous work has shown that systemic administration of Decitabine (DAC) induces sufficient expression of cancer-testis antigens (CTA) in GBM for ta…