Albert Wolkerstorfer
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View article: Treatment of vitiligo with ruxolitinib cream in the TRuE-V1 and TRuE-V2 studies: a plain language summary of publication
Treatment of vitiligo with ruxolitinib cream in the TRuE-V1 and TRuE-V2 studies: a plain language summary of publication Open
Summary What is this summary about? • This is a summary of a research article published in a medical journal that describes the main results from two studies called TRuE-V1 and TRuE-V2 • These studies looked at the use of ruxolitinib cream…
View article: A CollaboraTive Initiative of worldwide Vitiligo Experts and patients to define vitiligo activity (ACTIVE): study protocol
A CollaboraTive Initiative of worldwide Vitiligo Experts and patients to define vitiligo activity (ACTIVE): study protocol Open
By engaging international vitiligo experts and patients/patient representatives throughout the process, the ACTIVE study is designed to enhance consistency in disease activity definitions across multiple centers. This will improve the comp…
View article: Personalized medicine in vitiligo: A guide for daily practice
Personalized medicine in vitiligo: A guide for daily practice Open
Vitiligo is a chronic autoimmune depigmenting disorder with a complex clinical course and highly heterogeneous therapeutic response. Many disease‐specific and patient‐related factors determine the best personalized management in vitiligo. …
View article: Assessment of vitiligo in clinical practice: a cross-sectional survey among experts
Assessment of vitiligo in clinical practice: a cross-sectional survey among experts Open
This study shows similarities but also remarkable differences in assessed outcomes compared to the CDS for clinical trials. These results serve as a preparatory step toward developing a COS for clinical practice with the involvement of exp…
View article: Comprehensive Update on Keloid Management
Comprehensive Update on Keloid Management Open
Background: Keloids remain one of the most challenging conditions in cutaneous wound healing, marked by complex pathophysiology and notoriously high recurrence rates. Although a universally accepted standard of care is still lacking, recen…
View article: Immune and Biological Changes during Treatment in Patients with Nonsegmental Vitiligo and their Relation to Repigmentation
Immune and Biological Changes during Treatment in Patients with Nonsegmental Vitiligo and their Relation to Repigmentation Open
The treatment of nonsegmental vitiligo remains challenging and poorly understood. The aim of this study was to evaluate protein differences in lesional and nonlesional skin and changes of cellular and proteomic markers early in treatment i…
View article: Quality Analysis of Measurement Properties of Patient‐Reported Outcome Measures for Vitiligo and of the Studies Assessing Them: A Systematic Review
Quality Analysis of Measurement Properties of Patient‐Reported Outcome Measures for Vitiligo and of the Studies Assessing Them: A Systematic Review Open
Evaluating measurement properties (MPs) of Patient Reported Outcome Measures (PROMs) in vitiligo is essential for evidence‐based recommendations and identifying research gaps. This study assesses the quality of PROMs used in vitiligo. A sy…
View article: A Quality Analysis of the Measurement Properties of the Clinician-Reported Outcome Measures for Vitiligo and of the Studies Assessing Them: A Systematic Review
A Quality Analysis of the Measurement Properties of the Clinician-Reported Outcome Measures for Vitiligo and of the Studies Assessing Them: A Systematic Review Open
Background/Objective: Evaluating the measurement properties (MPs) of Clinician-Reported Outcome Measures (ClinROMs) is crucial for selecting appropriate instruments for vitiligo assessment. This review critically appraises the existing evi…
View article: Efficacy and Safety of Ruxolitinib Cream in Vitiligo by Patient Characteristic Subgroups: Descriptive Pooled Analysis From Two Phase 3 Studies
Efficacy and Safety of Ruxolitinib Cream in Vitiligo by Patient Characteristic Subgroups: Descriptive Pooled Analysis From Two Phase 3 Studies Open
View article: Impact of COVID‐19 disease and vaccination on dermatological immune‐mediated inflammatory diseases atopic dermatitis, psoriasis, and vitiligo: a Target2B! substudy
Impact of COVID‐19 disease and vaccination on dermatological immune‐mediated inflammatory diseases atopic dermatitis, psoriasis, and vitiligo: a Target2B! substudy Open
During the COVID‐19 pandemic, the daily life of many patients with dermatological immune‐mediated inflammatory diseases (DIMIDs), such as atopic dermatitis (AD), psoriasis, and vitiligo, was impacted by social restrictions caused by (fear …
View article: Incidence of nonmelanoma skin cancer in patients with vitiligo who applied ruxolitinib cream
Incidence of nonmelanoma skin cancer in patients with vitiligo who applied ruxolitinib cream Open
View article: KECORT Study: An International e-Delphi Study on the Treatment of KEloids Using Intralesional CORTicosteroids in Clinical Practice
KECORT Study: An International e-Delphi Study on the Treatment of KEloids Using Intralesional CORTicosteroids in Clinical Practice Open
View article: Effect of Keloid Properties on Treatment Efficacy: A Systematic Review
Effect of Keloid Properties on Treatment Efficacy: A Systematic Review Open
BACKGROUND The efficacy of keloid treatment in randomized studies is highly variable. However, no systematic review has been performed to evaluate the effect of different keloid properties on treatment efficacy. OBJECTIVE To identify clini…
View article: The biodistribution of triamcinolone acetonide injections in severe keloids: an exploratory three-dimensional fluorescent cryomicrotome study
The biodistribution of triamcinolone acetonide injections in severe keloids: an exploratory three-dimensional fluorescent cryomicrotome study Open
Intralesional corticosteroid injections are a first-line treatment for keloids; yet clinical treatment results are highly variable and often suboptimal. Variation in triamcinolone acetonide (TAC) biodistribution may be an important reason …
View article: Exploring the Severity Strata of Disease Activity and Repigmentation in Vitiligo Based on Validated Physician Global Assessment (PGA) Scores
Exploring the Severity Strata of Disease Activity and Repigmentation in Vitiligo Based on Validated Physician Global Assessment (PGA) Scores Open
Background/Objectives: There is currently no guidance on how to interpret the global degrees of activity (worsening) and repigmentation (improvement) in vitiligo. Stratification into global degrees can be completed for static evaluations (…
View article: Delayed Onset Type I Allergic Reaction Following Black Tattoo Removal Using Picosecond Laser
Delayed Onset Type I Allergic Reaction Following Black Tattoo Removal Using Picosecond Laser Open
Picosecond lasers are increasingly used as the mainstay laser technology alongside nanosecond lasers for removing tattoos. We present a unique case of a patient who developed progressive and recurrent Type I allergic reactions 1 week follo…
View article: Where two keloids meet: Invasive confluent growth of chest keloids, a case report
Where two keloids meet: Invasive confluent growth of chest keloids, a case report Open
View article: Characterization of Patient-Derived GNAQ Mutated Endothelial Cells from Capillary Malformations
Characterization of Patient-Derived GNAQ Mutated Endothelial Cells from Capillary Malformations Open
Capillary malformations (CM) (port-wine stains) are congenital skin lesions that are characterized by dilated capillaries and postcapillary venules. CMs are caused by altered functioning of the vascular endothelium. Somatic genetic mutatio…
View article: Needle‐free electronically‐controlled jet injector treatment with bleomycin and lidocaine is effective and well‐tolerated in patients with recalcitrant keloids
Needle‐free electronically‐controlled jet injector treatment with bleomycin and lidocaine is effective and well‐tolerated in patients with recalcitrant keloids Open
Objectives The treatment of recalcitrant keloids is challenging. Although intralesional bleomycin using conventional needle injectors (CNI) is effective, it has important drawbacks, such as the need for repetitive and painful injections. T…
View article: Needle-free electronically controlled jet injection with corticosteroids in recalcitrant keloid scars: a retrospective study and patient survey
Needle-free electronically controlled jet injection with corticosteroids in recalcitrant keloid scars: a retrospective study and patient survey Open
First-line treatment of keloids consists of intralesional needle injections with corticosteroids, but generally entails multiple painful sessions, resulting in variable clinical outcomes. Novel needle-free jet injectors may facilitate more…
View article: Issue Information
Issue Information Open
Our policy is to use permanent paper from mills that operate a sustainable forestry policy, and which has been manufactured from pulp that is processed using acid-free and elementary chlorine-free practices.Furthermore, we ensure that the …
View article: Worldwide expert recommendations for the diagnosis and management of vitiligo: Position statement from the International Vitiligo Task Force Part 1: towards a new management algorithm
Worldwide expert recommendations for the diagnosis and management of vitiligo: Position statement from the International Vitiligo Task Force Part 1: towards a new management algorithm Open
Background The treatment of vitiligo can be challenging and depends on several factors such as the subtype, disease activity, vitiligo extent, and treatment goals. Vitiligo usually requires a long‐term approach. To improve the management o…
View article: Worldwide expert recommendations for the diagnosis and management of vitiligo: Position statement from the international Vitiligo Task Force—Part 2: Specific treatment recommendations
Worldwide expert recommendations for the diagnosis and management of vitiligo: Position statement from the international Vitiligo Task Force—Part 2: Specific treatment recommendations Open
Background The treatment of vitiligo can be challenging. Up‐to‐date agreed consensus recommendations on the use of topical and systemic therapies to facilitate the clinical management of vitiligo are currently lacking. Objectives To develo…
View article: <scp>Clinician‐reported</scp> outcome measures for the assessment of vitiligo: A scoping review
<span>Clinician‐reported</span> outcome measures for the assessment of vitiligo: A scoping review Open
Clinician‐reported outcome measures (ClinROMs) are essential for assessment of vitiligo in clinical trials and daily practice. Several instruments have been developed and tested to measure, for example, vitiligo extent, repigmentation and …
View article: Trained immunity in the pathogenesis of vitiligo
Trained immunity in the pathogenesis of vitiligo Open
Vitiligo is caused by an autoimmune reaction against melanocytes leading to melanocyte loss. The cause of vitiligo is an interaction between genetic susceptibility and environmental factors. Both the adaptive immune system—through cytotoxi…
View article: Expert opinion about laser and intense pulsed light (IPL)-induced leukoderma or vitiligo: a cross-sectional survey study
Expert opinion about laser and intense pulsed light (IPL)-induced leukoderma or vitiligo: a cross-sectional survey study Open
View article: Consensus on the safety and risks of laser and intense pulse light treatments in patients with vitiligo: An e-Delphi study
Consensus on the safety and risks of laser and intense pulse light treatments in patients with vitiligo: An e-Delphi study Open
View article: Efficacy and safety of needle-free jet injector-assisted intralesional treatments in dermatology—a systematic review
Efficacy and safety of needle-free jet injector-assisted intralesional treatments in dermatology—a systematic review Open
View article: The <scp>JAK–STAT</scp> pathway in keloid pathogenesis: a systematic review with qualitative synthesis
The <span>JAK–STAT</span> pathway in keloid pathogenesis: a systematic review with qualitative synthesis Open
Keloid tissues contain inflammatory cells and upregulated pro‐inflammatory cytokines. The Janus kinase (JAK)‐signal transducer and activator of transcription (STAT) pathway mediate cellular responses to these cytokines. We performed a syst…
View article: Intralesional corticosteroid administration in the treatment of keloids: a survey among Dutch dermatologists and plastic surgeons
Intralesional corticosteroid administration in the treatment of keloids: a survey among Dutch dermatologists and plastic surgeons Open
Intralesional corticosteroid administration (ICA) is a first-line therapy in keloid treatment. However, its clinical results are still highly variable and often suboptimal. Treatment results may strongly be influenced by various ways of IC…