Alberto Bocchetta
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View article: Microcytic Anaemia as Susceptibility Factors in Bipolar Spectrum Disorders: Review of the Literature, Replication Survey, and Co-Segregation within Families
Microcytic Anaemia as Susceptibility Factors in Bipolar Spectrum Disorders: Review of the Literature, Replication Survey, and Co-Segregation within Families Open
Background: Potential interactions between mood disorders and microcytic anaemias have been suggested by case reports, surveys of haematological parameters in psychiatric populations, and surveys of psychiatric morbidity in thalassaemic ca…
View article: Exemplar scoring identifies genetically separable phenotypes of lithium responsive bipolar disorder
Exemplar scoring identifies genetically separable phenotypes of lithium responsive bipolar disorder Open
Predicting lithium response (LiR) in bipolar disorder (BD) may inform treatment planning, but phenotypic heterogeneity complicates discovery of genomic markers. We hypothesized that patients with “exemplary phenotypes”—those whose clinical…
View article: Telomere attrition and inflammatory load in severe psychiatric disorders and in response to psychotropic medications
Telomere attrition and inflammatory load in severe psychiatric disorders and in response to psychotropic medications Open
View article: Exemplar Scoring Identifies Genetically Separable Phenotypes of Lithium Responsive Bipolar Disorder
Exemplar Scoring Identifies Genetically Separable Phenotypes of Lithium Responsive Bipolar Disorder Open
Predicting lithium response (LiR) in bipolar disorder (BD) could expedite effective pharmacotherapy, but phenotypic heterogeneity of bipolar disorder has complicated the search for genomic markers. We thus sought to determine whether patie…
View article: A multidisciplinary approach to mental illness: do inflammation, telomere length and microbiota form a loop? A protocol for a cross-sectional study on the complex relationship between inflammation, telomere length, gut microbiota and psychiatric disorders
A multidisciplinary approach to mental illness: do inflammation, telomere length and microbiota form a loop? A protocol for a cross-sectional study on the complex relationship between inflammation, telomere length, gut microbiota and psychiatric disorders Open
Introduction Severe psychiatric disorders are typically associated with a significant reduction in life expectancy compared with the general population. Among the different hypotheses formulated to explain this observation, accelerated age…
View article: Psychotropic Medication of Acute Episodes of Mood Disorders: Current Prescription Attitude in Two Psychiatric Wards in Cagliari, Italy
Psychotropic Medication of Acute Episodes of Mood Disorders: Current Prescription Attitude in Two Psychiatric Wards in Cagliari, Italy Open
Background: Medication of acute episodes of mood disorders has changed over the last decades following the results of randomized clinical trials. Objective: The aim of this study was to analyze medication prescribed at discharge from two p…
View article: Internet use by older adults with bipolar disorder: international survey results
Internet use by older adults with bipolar disorder: international survey results Open
View article: Thyroid and renal tumors in patients treated with long-term lithium: case series from a lithium clinic, review of the literature and international pharmacovigilance reports
Thyroid and renal tumors in patients treated with long-term lithium: case series from a lithium clinic, review of the literature and international pharmacovigilance reports Open
So far it has not been possible epidemiologically to confirm an increased risk of thyroid or renal cancers associated with lithium. Such a conclusion is supported by the findings of low rates and mortalities of thyroid or renal cancers fro…
View article: Circulating antithyroid antibodies contribute to the decrease of glomerular filtration rate in lithium-treated patients: a longitudinal study
Circulating antithyroid antibodies contribute to the decrease of glomerular filtration rate in lithium-treated patients: a longitudinal study Open
View article: The Sardinian Puzzle: Concentration of Major Psychoses and Suicide in the Same Sub-Regions Across One Century
The Sardinian Puzzle: Concentration of Major Psychoses and Suicide in the Same Sub-Regions Across One Century Open
Background: Sardinia, the second largest Mediterranean island has long been considered a privileged observatory for the study of several medical conditions. The peculiar epidemiology of mood disorders and suicide across Sardinian sub-regio…
View article: International multi-site survey on the use of online support groups in bipolar disorder
International multi-site survey on the use of online support groups in bipolar disorder Open
The survey was completed by 1222 patients in 17 countries. The patients used the Internet at a percentage similar to the general public. Of the Internet users who looked online for information about bipolar disorder, only 21.0% read or par…
View article: Long-term lithium treatment in bipolar disorder: effects on glomerular filtration rate and other metabolic parameters
Long-term lithium treatment in bipolar disorder: effects on glomerular filtration rate and other metabolic parameters Open
View article: An observational study of 110 elderly lithium-treated patients followed up for 6 years with particular reference to renal function
An observational study of 110 elderly lithium-treated patients followed up for 6 years with particular reference to renal function Open
View article: Erratum to: Online information seeking by patients with bipolar disorder: results from an international multisite survey
Erratum to: Online information seeking by patients with bipolar disorder: results from an international multisite survey Open
View article: Reconsidering risk factors for renal dysfunction in lithium-treated patients
Reconsidering risk factors for renal dysfunction in lithium-treated patients Open
FROM: Clos S, Rauchhaus P, Severn A, et al . Long-term effect of lithium maintenance therapy on estimated glomerular filtration rate in patients with affective disorders: a population-based cohort study. Lancet Psychiatry 2015;2:1075–83.
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View article: Online information seeking by patients with bipolar disorder: results from an international multisite survey
Online information seeking by patients with bipolar disorder: results from an international multisite survey Open
View article: Internet use by patients with bipolar disorder: Results from an international multisite survey
Internet use by patients with bipolar disorder: Results from an international multisite survey Open
View article: Bipolar disorder and antithyroid antibodies: review and case series
Bipolar disorder and antithyroid antibodies: review and case series Open
View article: Long-term lithium and estimated glomerular filtration rate
Long-term lithium and estimated glomerular filtration rate Open
View article: Renal function during long-term lithium treatment: a cross-sectional and longitudinal study
Renal function during long-term lithium treatment: a cross-sectional and longitudinal study Open
Duration of lithium treatment is to be added to advancing age as a risk factor for reduced glomerular filtration rate. However, renal dysfunction tends to appear after decades of treatment and to progress slowly and irrespective of lithium…