Alberto Floris
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View article: The impact of demographics on organ damage in Behçet’s syndrome: a cross-sectional analysis of the international PROBE cohort
The impact of demographics on organ damage in Behçet’s syndrome: a cross-sectional analysis of the international PROBE cohort Open
Objective To examine the influence of demographics on organ damage in a broad, multiethnic cohort of patients with Behçet’s Syndrome (BS). Methods In this cross-sectional ancillary analysis of the PROBE project, the investigated demographi…
View article: The Risk of Developing Ocular Involvement Among Behçet’s Disease Patients Presenting with Mucocutaneous Involvement at Disease Onset: Data from the International AIDA Network Behçet’s Disease Registry
The Risk of Developing Ocular Involvement Among Behçet’s Disease Patients Presenting with Mucocutaneous Involvement at Disease Onset: Data from the International AIDA Network Behçet’s Disease Registry Open
Major oral aphthosis, genital aphthous attacks with more than five concurrent ulcers, erythema nodosum coexisting with pseudofolliculitis, a positive family history of BD, and Arab ethnicity are associated with a higher risk of ocular invo…
View article: Stratifying patients by TNFSF13B genotype revealed increased flare and renal flare risk, but a greater benefit from belimumab: a potential biomarker for personalized treatment in systemic lupus erythematosus
Stratifying patients by TNFSF13B genotype revealed increased flare and renal flare risk, but a greater benefit from belimumab: a potential biomarker for personalized treatment in systemic lupus erythematosus Open
Pending further validation, BAFF-var may serve as a predictive and prognostic biomarker for personalized treatment in SLE.
View article: OP0040 Trajectory and Determinants of Organ Damage Accrual in Behçet's Syndrome: 1-Year Preliminary Results from the PROBE Study
OP0040 Trajectory and Determinants of Organ Damage Accrual in Behçet's Syndrome: 1-Year Preliminary Results from the PROBE Study Open
View article: POS0824 RADIOGRAPHIC DAMAGE ACCRUAL IN PSORIATIC ARTHRITIS: INSIGHT INTO ASSOCIATIONS WITH DEMOGRAPHICS, CLINICAL FACTORS, DIFFICULT-TO-TREAT STATUS AND FUNCTIONAL IMPAIRMENT
POS0824 RADIOGRAPHIC DAMAGE ACCRUAL IN PSORIATIC ARTHRITIS: INSIGHT INTO ASSOCIATIONS WITH DEMOGRAPHICS, CLINICAL FACTORS, DIFFICULT-TO-TREAT STATUS AND FUNCTIONAL IMPAIRMENT Open
View article: BELIMUMAB REDUCES THE RISK OF FLARES ASSOCIATED WITH THE BAFF OVEREXPRESSING TNFSF13B GENE VARIANT: A HINT FOR PERSONALIZED TREATMENT IN SLE.
BELIMUMAB REDUCES THE RISK OF FLARES ASSOCIATED WITH THE BAFF OVEREXPRESSING TNFSF13B GENE VARIANT: A HINT FOR PERSONALIZED TREATMENT IN SLE. Open
PV183 / #357 Poster Topic: AS20 - Precision Medicine Background/Purpose The TNFSF13B gene functional variant (BAFFvar) is an insertion-deletion (GCTGT→A) introducing an alternative polyadenylation motif generating a truncated/shorter gene …
View article: Super-Eddington Accretion in Quasars
Super-Eddington Accretion in Quasars Open
This review provides an observational perspective on the fundamental properties of super-Eddington accretion onto supermassive black holes in quasars. It begins by outlining the selection criteria, particularly focusing on optical and UV b…
View article: The role of Anti-PAD4, Anti-CarP, and Anti-RA33 antibodies combined with RF and ACPA in predicting abatacept response in rheumatoid arthritis
The role of Anti-PAD4, Anti-CarP, and Anti-RA33 antibodies combined with RF and ACPA in predicting abatacept response in rheumatoid arthritis Open
This study highlights the potential benefits of using a combined assessment of ACPA aPAD4 and aCarP in predicting effectiveness of ABT in RA.
View article: Efficacy and retention rate of secukinumab in psoriatic arthritis across different clinical phenotypes: insights from the Italian GISEA Registry
Efficacy and retention rate of secukinumab in psoriatic arthritis across different clinical phenotypes: insights from the Italian GISEA Registry Open
Background: Randomized clinical trials have demonstrated the efficacy of secukinumab (SECU) in reducing disease activity in psoriatic arthritis (PsA), while real-world studies prove a broader perspective on SECU’s usefulness in everyday cl…
View article: Influence of gender on Behçet's disease phenotype and irreversible organ damage: Data from the International AIDA Network Behçet's Disease Registry
Influence of gender on Behçet's disease phenotype and irreversible organ damage: Data from the International AIDA Network Behçet's Disease Registry Open
View article: Efficacy and safety of infliximab or adalimumab in severe mucocutaneous Behçet's syndrome refractory to traditional immunosuppressants: a 6-month, multicentre, randomised controlled, prospective, parallel group, single-blind trial
Efficacy and safety of infliximab or adalimumab in severe mucocutaneous Behçet's syndrome refractory to traditional immunosuppressants: a 6-month, multicentre, randomised controlled, prospective, parallel group, single-blind trial Open
View article: Corrigendum to: Mood Disorder Questionnaire Positivity in Systemic Lupus Erythematosus and Other Chronic Diseases
Corrigendum to: Mood Disorder Questionnaire Positivity in Systemic Lupus Erythematosus and Other Chronic Diseases Open
[This corrects the article on p. e17450179303653 in vol. 20 PMC11318155.].
View article: Mood Disorder Questionnaire Positivity in Systemic Lupus Erythematosus and Other Chronic Diseases including Screen Bipolar Disorders or Rhythm and Energy Dysregulation Syndromes (DYMERS)
Mood Disorder Questionnaire Positivity in Systemic Lupus Erythematosus and Other Chronic Diseases including Screen Bipolar Disorders or Rhythm and Energy Dysregulation Syndromes (DYMERS) Open
Introduction This study explores the issue of paper-and-pencil screening tests for bipolar disorder, often leading to false positives. It discusses hypotheses that connect MDQ positivity with sleep disorders, a decline in health-related qu…
View article: Treatment of psoriasis with different classes of biologics reduces the likelihood of peripheral and axial psoriatic arthritis development
Treatment of psoriasis with different classes of biologics reduces the likelihood of peripheral and axial psoriatic arthritis development Open
Objective To assess the potential role of biologic treatment for psoriasis (PsO) in reducing the likelihood of psoriatic arthritis (PsA) development, through a detailed analysis that considered the different historical phases in PsA manage…
View article: Composite convolution: A flexible operator for deep learning on 3D point clouds
Composite convolution: A flexible operator for deep learning on 3D point clouds Open
Deep neural networks require specific layers to process point clouds, as the scattered and irregular location of 3D points prevents the use of conventional convolutional filters. We introduce the composite layer, a flexible and general alt…
View article: Effectiveness of ixekizumab over 24 months in different clinical scenarios in psoriatic arthritis: results from the Gruppo Italiano Studio Early Arthritis multicentric prospective registry
Effectiveness of ixekizumab over 24 months in different clinical scenarios in psoriatic arthritis: results from the Gruppo Italiano Studio Early Arthritis multicentric prospective registry Open
IXE effectiveness was highlighted after 6 months at both joint and skin levels and lasted up to 24 months in different clinical scenarios, making IXE effective in the complexity of managing PsA in a real-life setting.
View article: Psychometric Properties of Patient Global Assessment in Psoriatic Arthritis: A Systematic Literature Review
Psychometric Properties of Patient Global Assessment in Psoriatic Arthritis: A Systematic Literature Review Open
Objective Patient global assessment (PtGA) is a patient-reported outcome (PRO) that reflects a patient's judgment of their health/disease activity (DA). The objective of this systematic literature review was to assess the psychometric prop…
View article: Quality of Life in Systemic Lupus Erythematosus and Other Chronic Diseases: Highlighting the Amplified Impact of Depressive Episodes
Quality of Life in Systemic Lupus Erythematosus and Other Chronic Diseases: Highlighting the Amplified Impact of Depressive Episodes Open
Background: Extensive research has explored SLE’s impact on health-related quality of life (H-QoL), especially its connection with mental wellbeing. Recent evidence indicates that depressive syndromes significantly affect H-QoL in SLE. Thi…
View article: From sub-solar to super-solar chemical abundances along the quasar main sequence
From sub-solar to super-solar chemical abundances along the quasar main sequence Open
The 4D Eigenvector 1 sequence has proven to be a highly effective tool for organizing observational and physical properties of type 1 active galactic nuclei (AGN). In this paper, we present multiple measurements of metallicity for the broa…
View article: Long-Term Optical Monitoring of Broad-Line AGNs (LoTerm AGN): Case Study of NGC 3516
Long-Term Optical Monitoring of Broad-Line AGNs (LoTerm AGN): Case Study of NGC 3516 Open
Properties of the broad line region (BLR) in active galactic nuclei (AGNs) are commonly used to estimate the mass of the supermassive black hole (SMBH) that powers an AGN. However, the understanding of the physics behind the BLR remains in…
View article: Organ damage is a major determinant of work productivity impairment in Behçet’s syndrome: a post hoc analysis of the BODI validation study
Organ damage is a major determinant of work productivity impairment in Behçet’s syndrome: a post hoc analysis of the BODI validation study Open
Objectives To evaluate the prevalence, magnitude and potential determinants of work productivity impairment in patients with Behçet’s syndrome (BS), focusing on the role of irreversible organ damage. Methods A post hoc analysis of the BS O…
View article: Effect of anti-P ribosomal and anti-NR2 antibodies on depression and cognitive processes in SLE: an integrated clinical and functional MRI study
Effect of anti-P ribosomal and anti-NR2 antibodies on depression and cognitive processes in SLE: an integrated clinical and functional MRI study Open
Objectives To explore the effects of anti-ribosomal P protein (anti-P) and anti-N-methyl-D-aspartic acid receptor subunit 2 (anti-NR2) autoantibodies on depression and cognitive dysfunction and their relationships with functional brain con…
View article: Molecular profiling of clinical remission in psoriatic arthritis reveals dysregulation of FOS and CCDC50 genes: a gene expression study
Molecular profiling of clinical remission in psoriatic arthritis reveals dysregulation of FOS and CCDC50 genes: a gene expression study Open
Background In psoriatic arthritis (PsA), the primary goal of treatment is clinical remission. This study aimed to characterize the molecular profile underlying the induced clinical remission in patients with PsA, comparing the remission st…
View article: The Challenging Differentiation of Psoriatic Arthritis from Other Arthropathies and Nonspecific Arthralgias in Patients with Psoriasis: Results of a Cross-Sectional Rheumatologic Assessment of a Large Dermatologic Cohort
The Challenging Differentiation of Psoriatic Arthritis from Other Arthropathies and Nonspecific Arthralgias in Patients with Psoriasis: Results of a Cross-Sectional Rheumatologic Assessment of a Large Dermatologic Cohort Open
Aiming to identify the potential challenges in the classification of musculoskeletal manifestations in patients with psoriasis (PsO), this study analyzed the outcomes of a cross-sectional rheumatologic assessment of 1057 PsO patients. In t…
View article: Brain-reactive autoantibodies in neuropsychiatric systemic lupus erythematosus
Brain-reactive autoantibodies in neuropsychiatric systemic lupus erythematosus Open
Introduction The pathogenesis of neuropsychiatric systemic lupus erythematosus (NPSLE) is widely unknown, and the role of autoantibodies is still undetermined. Methods To identify brain-reactive autoantibodies possibly related to NPSLE, im…
View article: POS1172 GEOGRAPHICAL VARIABILITY OF ORGAN DAMAGE BURDEN IN A LARGE INTERNATIONAL MULTICENTER COHORT OF PATIENTS WITH BEHÇET'S SYNDROME: PRELIMINARY RESULTS OF THE PROBE STUDY
POS1172 GEOGRAPHICAL VARIABILITY OF ORGAN DAMAGE BURDEN IN A LARGE INTERNATIONAL MULTICENTER COHORT OF PATIENTS WITH BEHÇET'S SYNDROME: PRELIMINARY RESULTS OF THE PROBE STUDY Open
View article: POS0422 METABOLOMIC FINGERPRINT TO DISCRIMINATE REMISSION FROM ACTIVE DISEASE AND HEALTHY CONTROLS IN PSORIATIC ARTHRITIS
POS0422 METABOLOMIC FINGERPRINT TO DISCRIMINATE REMISSION FROM ACTIVE DISEASE AND HEALTHY CONTROLS IN PSORIATIC ARTHRITIS Open
View article: POS0691 ANALYSIS OF GAIT IN LONGSTANDING AXIAL-SPONDYLOARTHRITIS: A MONOCENTRIC PILOT STUDY
POS0691 ANALYSIS OF GAIT IN LONGSTANDING AXIAL-SPONDYLOARTHRITIS: A MONOCENTRIC PILOT STUDY Open
Background Progression of radiographic damage in axial-spondyloarthropaties is related to higher functionality impairment in longstanding patients, resulting in poorer quality of life and autonomy. Its impact on gait has not been extensive…
View article: Glucocorticoid tapering and associated outcome in patients with newly diagnosed systemic lupus erythematosus: the real-world GULP prospective observational study
Glucocorticoid tapering and associated outcome in patients with newly diagnosed systemic lupus erythematosus: the real-world GULP prospective observational study Open
Objective A subanalysis of the multicentre Early Lupus inception cohort was performed to investigate the real-world Glucocorticoids (GCs) Use in newly diagnosed systemic lupus erythematosus (SLE) Patients (GULP). Methods Patients starting …
View article: Accrual of organ damage in Behçet’s syndrome: trajectory, associated factors, and impact on patients’ quality of life over a 2-year prospective follow-up study
Accrual of organ damage in Behçet’s syndrome: trajectory, associated factors, and impact on patients’ quality of life over a 2-year prospective follow-up study Open
Background This study aimed to investigate the trajectory of damage accrual, associated factors, and impact on health-related quality of life (HR-QoL) in a multicenter cohort of patients with Behçet’s syndrome (BS) over 2 years of follow-u…