Alejandro F. Siller
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View article: Enhancing Recruitment Rate and Heterogeneity in the TrialNet Pathway to Prevention Study: Insights from a Single Center Experience
Enhancing Recruitment Rate and Heterogeneity in the TrialNet Pathway to Prevention Study: Insights from a Single Center Experience Open
Studies to predict and prevent type 1 diabetes (T1D) are limited by small numbers and lack of participation from all affected populations. We compared TrialNet Pathway to Prevention recruitments at one pediatric center 12 months before (Ju…
View article: Hypoglycemia risk with physical activity in type 1 diabetes: a data-driven approach
Hypoglycemia risk with physical activity in type 1 diabetes: a data-driven approach Open
Physical activity (PA) provides numerous health benefits for individuals with type 1 diabetes (T1D). However, the threat of exercise-induced hypoglycemia may impede the desire for regular PA. Therefore, we aimed to study the association be…
View article: Sex differences in circulating leptin as a marker of adiposity in obese or overweight adolescents with type 1 diabetes
Sex differences in circulating leptin as a marker of adiposity in obese or overweight adolescents with type 1 diabetes Open
Introduction We aimed to test whether the serum adipokines leptin and adiponectin are more strongly associated with body fat percentage (BF%) than body mass index (BMI) in adolescents with type 1 diabetes (T1D) and overweight/obesity. Rese…
View article: Inherited Deletion of 1q, Hyperparathyroidism and Signs of Y-chromosomal Influence in a Patient with Turner Syndrome
Inherited Deletion of 1q, Hyperparathyroidism and Signs of Y-chromosomal Influence in a Patient with Turner Syndrome Open
We report a detailed phenotypic, cytogenetic and molecular characterization of a patient prenatally diagnosed with Turner syndrome (TS). In addition to having typical TS clinical characteristics including webbed neck, high arched palate an…
View article: Inherited Deletion of 1q, Hyperparathyroidism, and Signs of Y-Chromosomal Influence in a Patient with Turner Syndrome
Inherited Deletion of 1q, Hyperparathyroidism, and Signs of Y-Chromosomal Influence in a Patient with Turner Syndrome Open
View article: Severity of clinical presentation in youth with type 1 diabetes is associated with differences in brain structure
Severity of clinical presentation in youth with type 1 diabetes is associated with differences in brain structure Open
These data suggest that severity of clinical presentation is an important factor in predicting brain structural differences in youth with type 1 diabetes approximately 3 months after diagnosis.
View article: Clinical presentation and memory function in youth with type 1 diabetes
Clinical presentation and memory function in youth with type 1 diabetes Open
DKA and degree of hyperglycemia exposure at diagnosis have implications for long-delay spatial memory function within 3.5 months of diagnosis. These findings suggest that early detection of T1DM, which decreases risk for prolonged exposure…