Patricia Muñóz
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View article: Latent classes of mental health disorders and their associations with polymorphisms of 5HTTLPR and BDNF in a Chilean primary care population
Latent classes of mental health disorders and their associations with polymorphisms of 5HTTLPR and BDNF in a Chilean primary care population Open
View article: Comparative effectiveness of echinocandins and liposomal amphotericin B for fluconazole-resistant <i>Candida parapsilosis</i> bloodstream infections
Comparative effectiveness of echinocandins and liposomal amphotericin B for fluconazole-resistant <i>Candida parapsilosis</i> bloodstream infections Open
Current therapeutic options for fluconazole-resistant Candida parapsilosis (FLZR-CP) bloodstream infections (BSI) are limited to echinocandins and liposomal amphotericin B (L-AmB). To the best of our knowledge, no real-world comparative ef…
View article: Direct nanopore sequencing of <i>M. tuberculosis</i> on sputa and rescue of suboptimal results to enhance transmission surveillance
Direct nanopore sequencing of <i>M. tuberculosis</i> on sputa and rescue of suboptimal results to enhance transmission surveillance Open
Summary Whole-genome sequencing (WGS) enhances precision in predicting antimicrobial resistance and tracking Mycobacterium tuberculosis (MTB) transmission. Due to MTB’s slow-growing nature, genomic results are delayed; however, few efforts…
View article: Correction: Current trends on antifungal prophylaxis in solid organ transplantation: a study from ESCMID-EFISG, ESCMID-ESGICH, SITA, and SEIMC-GESITRA-IC
Correction: Current trends on antifungal prophylaxis in solid organ transplantation: a study from ESCMID-EFISG, ESCMID-ESGICH, SITA, and SEIMC-GESITRA-IC Open
View article: Persistent candidemia caused by different Candida species: Data from a multicenter contemporary cohort
Persistent candidemia caused by different Candida species: Data from a multicenter contemporary cohort Open
Persistent candidemia affects one in four patients with Candida BSI. Infections caused by Candida parapsilosis or Candida auris require individualized management, with early source control being essential to reduce the risk of persistence.
View article: Epidemiology of resistant bacterial infections in patients with hematological malignancies or undergoing hematopoietic cell transplantation in Europe: A systematic review by the European Conference on Infections in Leukemia (ECIL)
Epidemiology of resistant bacterial infections in patients with hematological malignancies or undergoing hematopoietic cell transplantation in Europe: A systematic review by the European Conference on Infections in Leukemia (ECIL) Open
AMR presents an escalating challenge in febrile neutropenic HM/HCT patients with geographical variability and increasing resistance trends. These findings strongly support the need for updated guidelines, antimicrobial stewardship programs…
View article: Quantification and Comparison of Different Biofilm Components from Methicillin-Susceptible Staphylococcus aureus Treated with Tranexamic Acid Using an In Vitro Model
Quantification and Comparison of Different Biofilm Components from Methicillin-Susceptible Staphylococcus aureus Treated with Tranexamic Acid Using an In Vitro Model Open
As we previously demonstrated that tranexamic acid (TXA), an antifibrinolytic, showed an antibacterial effect alone and in combination with vancomycin and gentamicin, we now wanted to analyze its own efficacy using new, different fluoresce…
View article: Management of Clostridioides difficile infection in patients with haematological malignancies and after cellular therapy: guidelines from 10th European Conference on Infections in Leukaemia (ECIL-10)
Management of Clostridioides difficile infection in patients with haematological malignancies and after cellular therapy: guidelines from 10th European Conference on Infections in Leukaemia (ECIL-10) Open
View article: Redefinition of transmission clusters by accessing to additional diversity in Mycobacterium tuberculosis through long-read sequencing
Redefinition of transmission clusters by accessing to additional diversity in Mycobacterium tuberculosis through long-read sequencing Open
Whole-genome sequencing, supported on short-read-sequencing, has revolutionized the precision to track Mycobacterium tuberculosis (MTB) transmission. However, the complexity of the MTB genome (10% repetitive regions and 65% GC content) cha…
View article: Corrigendum to “Characterization of a nosocomial outbreak caused by VIM-1 Klebsiella michiganensis using Fourier transform infrared (FT-IR) spectroscopy” [J Hosp Infect 162 (2025) 9–16]
Corrigendum to “Characterization of a nosocomial outbreak caused by VIM-1 Klebsiella michiganensis using Fourier transform infrared (FT-IR) spectroscopy” [J Hosp Infect 162 (2025) 9–16] Open
View article: Assessment of the Anti-Biofilm Effect of Cefiderocol Against 28 Clinical Strains of Multidrug-Resistant Gram-Negative Bacilli
Assessment of the Anti-Biofilm Effect of Cefiderocol Against 28 Clinical Strains of Multidrug-Resistant Gram-Negative Bacilli Open
Objectives: Cefideroccol (FDC) is a siderophore cephalosporin with potent antibacterial activity against a wide range of Gram-negative multidrug-resistant (MDR) microorganisms. We investigated the anti-biofilm capacity of FDC against clini…
View article: Current trends on antifungal prophylaxis in solid organ transplantation: a study from ESCMID-EFISG, ESCMID-ESGICH, SITA, and SEIMC-GESITRA-IC
Current trends on antifungal prophylaxis in solid organ transplantation: a study from ESCMID-EFISG, ESCMID-ESGICH, SITA, and SEIMC-GESITRA-IC Open
Introduction Invasive fungal diseases (IFD) present serious risks to solid organ transplant recipients, particularly in the first 180 days post-transplant. Existing European and US guidelines offer limited evidence, prompting a shift away …
View article: Is Time to Positivity in <i>Staphylococcus aureus</i> Bacteremia a Harbinger of Endocarditis?
Is Time to Positivity in <i>Staphylococcus aureus</i> Bacteremia a Harbinger of Endocarditis? Open
View article: Trends in Candidemia Over the Last 14 Years: A Comparative Analysis of <i>Candida parapsilosis</i> and <i>Candida albicans</i>
Trends in Candidemia Over the Last 14 Years: A Comparative Analysis of <i>Candida parapsilosis</i> and <i>Candida albicans</i> Open
Background Data on the trends of the incidence of candidemia caused by C. albicans and C. parapsilosis in recent years are very limited. At the same time, factors that predispose to candidemia, caused by both species and the epidemiology o…
View article: Is It Possible to Optimize the Elaboration and Preservation of a Vancomycin Catheter Lock Solution?
Is It Possible to Optimize the Elaboration and Preservation of a Vancomycin Catheter Lock Solution? Open
Background/Objectives: Vancomycin (V) is widely used for catheter lock therapy. However, its ad hoc preparation in pharmacy departments involves discarding most of an intravenous vial and contributes to high workload. We aimed to assess th…
View article: Development of a toxin-selective immunotracer for in vivo detection of Clostridioides difficile infection by immunoPET
Development of a toxin-selective immunotracer for in vivo detection of Clostridioides difficile infection by immunoPET Open
View article: Evaluation of Perioperative Risk Factors for Infection by Multidrug-Resistant Bacteria in Patients Undergoing Liver Transplantation
Evaluation of Perioperative Risk Factors for Infection by Multidrug-Resistant Bacteria in Patients Undergoing Liver Transplantation Open
Background: Liver transplantation (LT) is a critical intervention for patients with end-stage liver disease. Infections caused by multidrug-resistant bacteria (MDRB) significantly worsen post-transplant outcomes. The main objective of this…
View article: A prospective randomized study that compares three different dressings for the prevention of surgical site infections following major heart surgery
A prospective randomized study that compares three different dressings for the prevention of surgical site infections following major heart surgery Open
Surgical site infection (SSI) is among the most common complication of major heart surgery patients with incidences ranging from 0.5 to 16.5%. Our aim was to compare the incidence, etiology and prognosis of surgical wound infection in thre…
View article: Effectiveness of the BioFire FilmArray for the rapid detection of bloodstream infection in haematological patients with febrile neutropenia (the ONFIRE study): study protocol of a prospective, multicentre observational study at three reference university hospitals in Spain
Effectiveness of the BioFire FilmArray for the rapid detection of bloodstream infection in haematological patients with febrile neutropenia (the ONFIRE study): study protocol of a prospective, multicentre observational study at three reference university hospitals in Spain Open
Introduction Bloodstream infection (BSI) due to multidrug-resistant Gram-negative bacilli is a serious global health problem that has a profound impact on severely immunosuppressed neutropenic haematological patients. Prompt institution of…
View article: Corrigendum to “In vitro study to assess modulation of Candida biofilm by Escherichia coli from vaginal strains” [Biofilm 5 (2023) 100116]
Corrigendum to “In vitro study to assess modulation of Candida biofilm by Escherichia coli from vaginal strains” [Biofilm 5 (2023) 100116] Open
View article: Evolution of postsurgical mediastinitis after Major Heart Surgery (MHS) in the last 12 years: Are we improving?
Evolution of postsurgical mediastinitis after Major Heart Surgery (MHS) in the last 12 years: Are we improving? Open
Background: Postsurgical mediastinitis (PSM) is a serious and potentially life-threatening complication of Major Heart Surgery (MHS). Data on the evolution of the incidence of PSM after MHS in large series of operated patients in recent ye…
View article: Surveillance of nasal <i>Staphylococcus aureus</i> in patients undergoing breast surgery
Surveillance of nasal <i>Staphylococcus aureus</i> in patients undergoing breast surgery Open
Screening and decolonization programs have proven effective in reducing the frequency of Staphylococcus aureus infections, mainly in orthopedic and cardiac procedures. Despite being classified as clean, breast surgery is associated with in…
View article: Development of a Toxin-selective immunotracer for the specific in vivo detection of Clostridioides difficile infection by immunoPET
Development of a Toxin-selective immunotracer for the specific in vivo detection of Clostridioides difficile infection by immunoPET Open
Background: Clostridioides difficile infection (CDI) is a major healthcare challenge, associated with high morbidity and mortality. Current diagnostic methods have limitations in specificity and invasiveness, necessitating the development …
View article: Current Performance of MALDI–TOF Mass Spectrometry Databases for the Identification of Dermatophyte Species
Current Performance of MALDI–TOF Mass Spectrometry Databases for the Identification of Dermatophyte Species Open
The identification of filamentous fungi by matrix-assisted laser desorption/ionization–time of flight mass spectrometry (MALDI–TOF MS) represents a challenge due to their complex taxonomy and the lack of comprehensive databases. The aim of…
View article: C07. INFECCIONES EN PACIENTES PORTADORES DE DISPOSITIVOS HEARTMATE
C07. INFECCIONES EN PACIENTES PORTADORES DE DISPOSITIVOS HEARTMATE Open
View article: C07. RENTABILIDAD DIAGNÓSTICA DE LA SEROLOGÍA PARA LEGIONELLA, MYCOPLASMA Y CHLAMYDIA EN LA ENDOCARDITIS INFECCIOSA, ¿ES HORA DE DECIR ADIÓS?
C07. RENTABILIDAD DIAGNÓSTICA DE LA SEROLOGÍA PARA LEGIONELLA, MYCOPLASMA Y CHLAMYDIA EN LA ENDOCARDITIS INFECCIOSA, ¿ES HORA DE DECIR ADIÓS? Open
View article: Safety and immunogenicity of PHH-1V booster against SARS-CoV-2 variants, including omicron subvariants: Results from a phase IIb open-label extension study
Safety and immunogenicity of PHH-1V booster against SARS-CoV-2 variants, including omicron subvariants: Results from a phase IIb open-label extension study Open
SARS-CoV-2 vaccination campaigns on current endemic situation would benefit from vaccine alternatives with easy logistics and accessibility, sustained response and cross-reactivity against emerging variants. Herein, safety and immunogenici…
View article: Reliability of differential time to positivity technique for diagnosing catheter-related bloodstream infections: a retrospective analysis
Reliability of differential time to positivity technique for diagnosing catheter-related bloodstream infections: a retrospective analysis Open
The differential time to positivity (DTTP) technique is the recommended conservative procedure to diagnose catheter-related bloodstream infection (C-RBSI). However, its reliability and accuracy remain under debate. Therefore, we aimed to c…
View article: New insights in the role of Candida biofilm in the pathogenesis of recurrent vulvovaginal candidiasis: a prospective clinical study
New insights in the role of Candida biofilm in the pathogenesis of recurrent vulvovaginal candidiasis: a prospective clinical study Open
Background Despite the pathogenesis of vulvovaginal candidiasis (VVC) is multifactorial, this study aimed to assess whether phenotypic characteristics, such as biofilm production and quality, along with clinical symptoms, are associated wi…
View article: A rationalized molecular and genomic strategy to get a snapshot of the tuberculosis peri-pandemic transmission in Madrid
A rationalized molecular and genomic strategy to get a snapshot of the tuberculosis peri-pandemic transmission in Madrid Open
Genomic epidemiology has improved our understanding of tuberculosis (TB) transmission, overpassing the lower discriminatory MIRU-VNTR analysis. However, universal long-term genomic analysis is required to properly identify transmission clu…