Alessandra Fusco
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View article: Antibacterial and Antifungal Potential of Hermetia illucens Hemolymph Contained-Peptides
Antibacterial and Antifungal Potential of Hermetia illucens Hemolymph Contained-Peptides Open
Antimicrobial peptides (AMPs) constitute a chemically and structurally heterogeneous family of molecules produced by a wide range of living organisms, including plants, fish, amphibians, mammals, and insects. Their expression is particular…
View article: Lactococcus lactis I7 isolated from traditional Italian cheese making: a biotechnological integrated platform
Lactococcus lactis I7 isolated from traditional Italian cheese making: a biotechnological integrated platform Open
This paper focused its attention on optimization of fermentation conditions (in particular a vegan grade media using Design of Experiment approach) using fed-batch and microfiltration processes increasing the production of biomass and bioa…
View article: <i>Hermetia illucens</i>-Derived Chitosan: A Promising Immunomodulatory Agent for Applications in Biomedical Fields
<i>Hermetia illucens</i>-Derived Chitosan: A Promising Immunomodulatory Agent for Applications in Biomedical Fields Open
Chitosan, renowned for its important biological properties, is a valuable pharmaceutical excipient for different therapeutic approaches. Currently, the demand for the biopolymer on the market is growing, and, for this reason, it is importa…
View article: Characterization of Pseudomonas Aeruginosa Biofilms Grown on Different Substrates by Means of FT-IR Spectroscopy
Characterization of Pseudomonas Aeruginosa Biofilms Grown on Different Substrates by Means of FT-IR Spectroscopy Open
Fourier transform infrared spectroscopy (FT-IR) is a vibrational technique largely adopted for the study of bacterial biofilms. FT-IR is a non-destructive method allowing multiple analyses of the same biofilm. Pseudomonas aeruginosa…
View article: Tunable ciprofloxacin delivery through personalized electrospun patches for tympanic membrane perforations
Tunable ciprofloxacin delivery through personalized electrospun patches for tympanic membrane perforations Open
View article: Probiotic Properties of Lactococcus lactis Strains Isolated from Natural Whey Starter Cultures
Probiotic Properties of Lactococcus lactis Strains Isolated from Natural Whey Starter Cultures Open
Lactococcus lactis is a lactic acid bacterium (LAB), generally recognized as safe, and has been widely used in the food industry, especially in fermented dairy products. Numerous studies have evaluated the technological and probiotic prope…
View article: Leading by Example: A Call to Action for the New Committee “I.S.Mu.L.T. Sport and Disability” to Promote the Benefits of Sports for Individuals with Severe Disabilities
Leading by Example: A Call to Action for the New Committee “I.S.Mu.L.T. Sport and Disability” to Promote the Benefits of Sports for Individuals with Severe Disabilities Open
SCOPUS: ed.j
View article: Screening, Diagnosis, and Treatment of Patients with Binge Eating Disorder and Obesity: What the Endocrinologist Needs to Know
Screening, Diagnosis, and Treatment of Patients with Binge Eating Disorder and Obesity: What the Endocrinologist Needs to Know Open
Binge eating disorder (BED) is the most common eating disorder categorized in the DSM-V, but it is often not diagnosed in patients with obesity because it can be difficult to detect in these patients who often have altered eating patterns.…
View article: Screening, Diagnosis and Treatment of Patients with Binge Eating Disorder and Obesity: What the Endocrinologist Need to Know
Screening, Diagnosis and Treatment of Patients with Binge Eating Disorder and Obesity: What the Endocrinologist Need to Know Open
Background Binge eating disorder (BED) is the most common eating disorder, categorized in DSM-V, but many patients are not diagnosed, because of the difficulty to consider BED distinct condition from obesity. Its identification is importan…
View article: Regulatory Ability of Lactiplantibacillus plantarum on Human Skin Health by Counteracting In Vitro Malassezia furfur Effects
Regulatory Ability of Lactiplantibacillus plantarum on Human Skin Health by Counteracting In Vitro Malassezia furfur Effects Open
The skin serves as the first barrier against pathogen attacks, thanks to its multifunctional microbial community. Malassezia furfur is a commensal organism of normal cutaneous microflora but is also a cause of skin diseases. It acts on dif…
View article: Biopolymer- and Natural Fiber-Based Biomimetic Tissues to Realize Smart Cosmeceuticals and Nutraceuticals Using an Innovative Approach
Biopolymer- and Natural Fiber-Based Biomimetic Tissues to Realize Smart Cosmeceuticals and Nutraceuticals Using an Innovative Approach Open
More sustainable and smart cosmeceuticals and nutraceuticals are necessary due to the ecological transition. In this study, a pullulan-based water solution containing chitin nanofibril–nano-lignin (CN-LG) complexes that encapsulate fish co…
View article: Oreoch-1: A Peptide from Oreochromis niloticus as a Potential Tool against Staphylococci
Oreoch-1: A Peptide from Oreochromis niloticus as a Potential Tool against Staphylococci Open
Staphylococci, including Staphylococcus aureus and Staphylococcus epidermidis, are important human pathogens associated with potentially life-threatening infections. Their great biofilm-producing ability and the development of resistance m…
View article: Evaluation of Different Activity of Lactobacillus spp. against Two Proteus mirabilis Isolated Clinical Strains in Different Anatomical Sites In Vitro: An Explorative Study to Improve the Therapeutic Approach
Evaluation of Different Activity of Lactobacillus spp. against Two Proteus mirabilis Isolated Clinical Strains in Different Anatomical Sites In Vitro: An Explorative Study to Improve the Therapeutic Approach Open
Urinary tract infections (UTIs) and catheter-associated UTIs (CAUTIs) are the principal hospital-acquired infections. Between these, bacterial prostatitis is believed to be the leading cause of recurrent UTIs in men under 50 years of age a…
View article: In Vitro Evaluation of the Most Active Probiotic Strains Able to Improve the Intestinal Barrier Functions and to Prevent Inflammatory Diseases of the Gastrointestinal System
In Vitro Evaluation of the Most Active Probiotic Strains Able to Improve the Intestinal Barrier Functions and to Prevent Inflammatory Diseases of the Gastrointestinal System Open
Background: The integrity of the intestinal barrier is fundamental to gut health and homeostasis; its damage can increase intestinal permeability, with translocation of bacteria and/or endotoxins from gut, and the onset of various intestin…
View article: An Unconventional Oral Candidiasis in an Immunocompetent Patient
An Unconventional Oral Candidiasis in an Immunocompetent Patient Open
Oral candidiasis (OC) is an opportunistic fungal infection of the oral mucosae, sustained by Candida albicans or other non-albican Candida species (NAC), usually eradicated by conventional antifungals of the classes of azoles, polyenes, or…
View article: Clinical and microbiological efficacy of indocyanine green-based antimicrobial photodynamic therapy as an adjunct to non-surgical treatment of periodontitis: a randomized controlled clinical trial
Clinical and microbiological efficacy of indocyanine green-based antimicrobial photodynamic therapy as an adjunct to non-surgical treatment of periodontitis: a randomized controlled clinical trial Open
Objectives The aim of the present randomized clinical trial (RCT) with a parallel arm design was to evaluate the clinical and microbiological efficacy of repeated ICG-aPDT as an adjunct to full-mouth subgingival debridement in the treatmen…
View article: Photocatalytic activity of P-doped TiO2 photocatalyst
Photocatalytic activity of P-doped TiO2 photocatalyst Open
In this study, P-doped TiO 2 photocatalysts with different molar percentages (in the range 0.071–1.25 mol %) of the non-metallic element were prepared and their photocatalytic activity under visible light irradiation was tested. All achiev…
View article: Tunable Ciprofloxacin Delivery Through Personalized Electrospun Patches for Tympanic Membrane Perforations
Tunable Ciprofloxacin Delivery Through Personalized Electrospun Patches for Tympanic Membrane Perforations Open
View article: Older Adults with Type 2 Diabetes Treated with Metformin: AME-METStudy - A Multicentric Real-world Study in Italy
Older Adults with Type 2 Diabetes Treated with Metformin: AME-METStudy - A Multicentric Real-world Study in Italy Open
Aims: Metformin is the most widely used drug for the first-line treatment of type 2 diabetes mellitus (T2DM), but its use and schedule have been poorly investigated in elderly patients. Methods: We conducted an observational, cross-section…
View article: Optimization of growth of Levilactobacillus brevis SP 48 and in vitro evaluation of the effect of viable cells and high molecular weight potential postbiotics on Helicobacter pylori
Optimization of growth of Levilactobacillus brevis SP 48 and in vitro evaluation of the effect of viable cells and high molecular weight potential postbiotics on Helicobacter pylori Open
Several Levilactobacillus brevis strains have the potential to be used as probiotics since they provide health benefits due to the interaction of live cells, and of their secreted products, with the host (tissues). Therefore, the developme…
View article: Antimicrobial peptide human β-defensin-2 improves in vitro cellular viability and reduces pro-inflammatory effects induced by enteroinvasive Escherichia coli in Caco-2 cells by inhibiting invasion and virulence factors’ expression
Antimicrobial peptide human β-defensin-2 improves in vitro cellular viability and reduces pro-inflammatory effects induced by enteroinvasive Escherichia coli in Caco-2 cells by inhibiting invasion and virulence factors’ expression Open
Escherichia coli is one of the commensal species most represented in the intestinal microbiota. However, there are some strains that can acquire new virulence factors that enable them to adapt to new intestinal niches. These include entero…
View article: Hydroxychloroquine Blood Concentrations Can Be Clinically Relevant Also After Drug Discontinuation
Hydroxychloroquine Blood Concentrations Can Be Clinically Relevant Also After Drug Discontinuation Open
The study confirms the long half-life of hydroxychloroquine and its effect on the corrected QT interval even after short-term courses of the drug. This can inform the clinician using hydroxychloroquine treatments that it would be safer to …
View article: P341 DANTE (DIAGNOSTIC ACUTE PATIENT TOOL IN EMERGENCY) & BEATRICE (BEDSIDE ECHOCARDIOGRAPHIC ASSESMENT FOR IMPROVE CLINICAL EVALUATION) FOR GERIATRIC PATIENTS
P341 DANTE (DIAGNOSTIC ACUTE PATIENT TOOL IN EMERGENCY) & BEATRICE (BEDSIDE ECHOCARDIOGRAPHIC ASSESMENT FOR IMPROVE CLINICAL EVALUATION) FOR GERIATRIC PATIENTS Open
Objectives To determine whether comprehensive quantitative bed side echocardiogram could be used as a usual assessment tool in acute geriatric patients and to assess its effect on patient care. Design Retrospective. Setting: DEA di II live…
View article: Limosilactobacillus fermentum from buffalo milk is suitable for potential biotechnological process development and inhibits Helicobacter pylori in a gastric epithelial cell model
Limosilactobacillus fermentum from buffalo milk is suitable for potential biotechnological process development and inhibits Helicobacter pylori in a gastric epithelial cell model Open
View article: Chitin Nanofibril-Nanolignin Complexes as Carriers of Functional Molecules for Skin Contact Applications
Chitin Nanofibril-Nanolignin Complexes as Carriers of Functional Molecules for Skin Contact Applications Open
Chitin nanofibrils (CN) and nanolignin (NL) were used to embed active molecules, such as vitamin E, sodium ascorbyl phosphate, lutein, nicotinamide and glycyrrhetinic acid (derived from licorice), in the design of antimicrobial, anti-infla…
View article: Impact of COVID‐19 in immunosuppressive drug‐naïve autoimmune disorders: Autoimmune gastritis, celiac disease, type 1 diabetes, and autoimmune thyroid disease
Impact of COVID‐19 in immunosuppressive drug‐naïve autoimmune disorders: Autoimmune gastritis, celiac disease, type 1 diabetes, and autoimmune thyroid disease Open
Few conflicting data are currently available on the risk of SARS‐CoV‐2 infection in patients with autoimmune disorders. The studies performed so far are influenced, in most cases, by the treatment with immunosuppressive drugs, making it di…
View article: Chitin Nanofibril Application in Tympanic Membrane Scaffolds to Modulate Inflammatory and Immune Response
Chitin Nanofibril Application in Tympanic Membrane Scaffolds to Modulate Inflammatory and Immune Response Open
Chitin nanofibrils (CNs) are an emerging bio-based nanomaterial. Due to nanometric size and high crystallinity, CNs lose the allergenic features of chitin and interestingly acquire anti-inflammatory activity. Here we investigate the possib…
View article: Silver Nanoparticle-Coated Polyhydroxyalkanoate Based Electrospun Fibers for Wound Dressing Applications
Silver Nanoparticle-Coated Polyhydroxyalkanoate Based Electrospun Fibers for Wound Dressing Applications Open
Wound dressings are high performance and high value products which can improve the regeneration of damaged skin. In these products, bioresorption and biocompatibility play a key role. The aim of this study is to provide progress in this ar…
View article: V-Gel® Guided Endotracheal Intubation in Rabbits
V-Gel® Guided Endotracheal Intubation in Rabbits Open
Background: General anesthesia in rabbits is associated with higher morbidity and mortality relative to other mammalian species commonly anesthetized. Unique challenges related to endotracheal intubation (ETI) in rabbits contribute to this…
View article: Electrosprayed Shrimp and Mushroom Nanochitins on Cellulose Tissue for Skin Contact Application
Electrosprayed Shrimp and Mushroom Nanochitins on Cellulose Tissue for Skin Contact Application Open
Cosmetics has recently focused on biobased skin-compatible materials. Materials from natural sources can be used to produce more sustainable skin contact products with enhanced bioactivity. Surface functionalization using natural-based nan…