Alessandra S Orfanó
YOU?
Author Swipe
View article: <i>Anopheles</i> mosquitoes exposed to long-acting antimalarials via drug-spiked bloodmeal absorb drug but do not suffer fitness costs
<i>Anopheles</i> mosquitoes exposed to long-acting antimalarials via drug-spiked bloodmeal absorb drug but do not suffer fitness costs Open
The World Health Organization’s recommendations regarding the use of antimalarials for the prevention of malaria in endemic areas have greatly expanded, allowing more flexibility in the demographic groups and regions where chemoprevention …
View article: Structure-guided insights into potential function of novel genetic variants in the malaria vaccine candidate PfRh5
Structure-guided insights into potential function of novel genetic variants in the malaria vaccine candidate PfRh5 Open
The recent stall in the global reduction of malaria deaths has made the development of a highly effective vaccine essential. A major challenge to developing an efficacious vaccine is the extensive diversity of Plasmodium falciparum antigen…
View article: Corrigendum to: Morphological Characterization of the Antennal Sensilla of the Afrotropical Sand Fly, <i>Phlebotomus duboscqi</i> (Diptera: Psychodidae)
Corrigendum to: Morphological Characterization of the Antennal Sensilla of the Afrotropical Sand Fly, <i>Phlebotomus duboscqi</i> (Diptera: Psychodidae) Open
Laboratory of Insects and Parasites Biochemistry. Carlos Chagas Filho Biophysics Institute. Federal University of Rio de Janeiro. Rio de Janeiro, RJ, Brazil
View article: Morphological Characterization of the Antennal Sensilla of the Afrotropical Sand Fly,<i>Phlebotomus duboscqi</i>(Diptera: Psychodidae)
Morphological Characterization of the Antennal Sensilla of the Afrotropical Sand Fly,<i>Phlebotomus duboscqi</i>(Diptera: Psychodidae) Open
We investigated by scanning electron microscopy the morphology, distribution, and abundance of antennal sensilla of females Phlebotomus duboscqi sand fly, an important vector of zoonotic cutaneous leishmaniasis at Afrotropical region. Thir…
View article: Ultrastructure of the Antennae and Sensilla of<i>Nyssomyia intermedia</i>(Diptera: Psychodidae), Vector of American Cutaneous Leishmaniasis
Ultrastructure of the Antennae and Sensilla of<i>Nyssomyia intermedia</i>(Diptera: Psychodidae), Vector of American Cutaneous Leishmaniasis Open
The antennal sensilla and the antenna of females Nyssomyia intermedia, one of the main vectors of American cutaneous leishmaniasis, were studied by scanning electron microscopy. The main goal was to characterize the quantity, typology, and…
View article: Characterization of the complete mitogenome of Anopheles aquasalis, and phylogenetic divergences among Anopheles from diverse geographic zones
Characterization of the complete mitogenome of Anopheles aquasalis, and phylogenetic divergences among Anopheles from diverse geographic zones Open
Whole mitogenome sequences (mtDNA) have been exploited for insect ecology studies, using them as molecular markers to reconstruct phylogenies, or to infer phylogeographic relationships and gene flow. Recent Anopheles phylogenomic studies h…
View article: Microanatomy of the American Malaria Vector Anopheles aquasalis (Diptera: Culicidae: Anophelinae) Midgut: Ultrastructural and Histochemical Observations
Microanatomy of the American Malaria Vector Anopheles aquasalis (Diptera: Culicidae: Anophelinae) Midgut: Ultrastructural and Histochemical Observations Open
The mosquito gut is divided into foregut, midgut, and hindgut. The midgut functions in storage and digestion of the bloodmeal. This study used light, scanning (SEM), and transmission (TEM) electron microscopy to analyze in detail the micro…
View article: The Midgut Muscle Network of<i>Anopheles aquasalis</i>(Culicidae, Anophelinae): Microanatomy and Structural Modification After Blood Meal and<i>Plasmodium vivax</i>(Haemosporida, Plasmodiidae) Infection
The Midgut Muscle Network of<i>Anopheles aquasalis</i>(Culicidae, Anophelinae): Microanatomy and Structural Modification After Blood Meal and<i>Plasmodium vivax</i>(Haemosporida, Plasmodiidae) Infection Open
The mosquito midgut is divided into two regions named anterior midgut (AMG) and posterior midgut (PMG). The midgut expands intensely after the blood ingestion to accommodate a large amount of ingested food. To efficiently support the blood…
View article: Coinfection with Zika Virus (ZIKV) and Dengue Virus Results in Preferential ZIKV Transmission by Vector Bite to Vertebrate Host
Coinfection with Zika Virus (ZIKV) and Dengue Virus Results in Preferential ZIKV Transmission by Vector Bite to Vertebrate Host Open
This finding suggests that A. aegypti is an efficient vector of ZIKV and that ZIKV would be preferentially transmitted by coinfected A. aegypti. Coinfection in the vector population should be considered a new critical epidemiological facto…
View article: The role of the peritrophic matrix and red blood cell concentration in Plasmodium vivax infection of Anopheles aquasalis
The role of the peritrophic matrix and red blood cell concentration in Plasmodium vivax infection of Anopheles aquasalis Open
View article: Promising approach to reducing Malaria transmission by ivermectin: Sporontocidal effect against Plasmodium vivax in the South American vectors Anopheles aquasalis and Anopheles darlingi
Promising approach to reducing Malaria transmission by ivermectin: Sporontocidal effect against Plasmodium vivax in the South American vectors Anopheles aquasalis and Anopheles darlingi Open
In conclusion, whole blood spiked with IVM reduced the infection rate of P. vivax in An. aquasalis and An. darlingi, and increased the mortality of mosquitoes. Plasma from healthy volunteers after IVM administration affect asexual P. vivax…
View article: Zika virus infection modulates the bacterial diversity associated with Aedes aegypti as revealed by metagenomic analysis
Zika virus infection modulates the bacterial diversity associated with Aedes aegypti as revealed by metagenomic analysis Open
Zika is a re-emerging infection that has been considered a major threat to global public health. Currently at least 100 countries are at risk of Zika virus (ZIKV) transmission. Aedes aegypti is the main mosquito vector in the Americas. Thi…
View article: Bacterial diversity of wild-caught Lutzomyia longipalpis (a vector of zoonotic visceral leishmaniasis in Brazil) under distinct physiological conditions by metagenomics analysis
Bacterial diversity of wild-caught Lutzomyia longipalpis (a vector of zoonotic visceral leishmaniasis in Brazil) under distinct physiological conditions by metagenomics analysis Open
The observed dynamic nature of the bacterial community expands the knowledge pertaining to the tripartite host-microbiota-pathogen interactions. Further studies addressing how laboratory and field collected communities differ are critical …
View article: Zika virus transmission to mouse ear by mosquito bite: a laboratory model that replicates the natural transmission process
Zika virus transmission to mouse ear by mosquito bite: a laboratory model that replicates the natural transmission process Open
View article: Plasmodium yoelii nigeriensis (N67) Is a Robust Animal Model to Study Malaria Transmission by South American Anopheline Mosquitoes
Plasmodium yoelii nigeriensis (N67) Is a Robust Animal Model to Study Malaria Transmission by South American Anopheline Mosquitoes Open
Malaria is endemic in the American continent and the Amazonian rainforest is the region with the highest risk of transmission. However, the lack of suitable experimental models to infect malaria vectors from the Americas has limited the pr…
View article: Species-specific escape of Plasmodium sporozoites from oocysts of avian, rodent, and human malarial parasites
Species-specific escape of Plasmodium sporozoites from oocysts of avian, rodent, and human malarial parasites Open
View article: An overview of malaria transmission from the perspective of Amazon Anopheles vectors
An overview of malaria transmission from the perspective of Amazon Anopheles vectors Open
In the Americas, areas with a high risk of malaria transmission are mainly located in the Amazon Forest, which extends across nine countries. One keystone step to understanding the Plasmodium life cycle in Anopheles species from the Amazon…