Alessandro Poli
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View article: A response matrix determined with a coincidence-based acquisition for correction of charge sharing spectral distortions in energy-resolved photon counting detectors
A response matrix determined with a coincidence-based acquisition for correction of charge sharing spectral distortions in energy-resolved photon counting detectors Open
A model-independent method is proposed to characterize and correct charge sharing spectral distortions in energy-resolved X-ray acquisitions with pixellated photon-counting detectors. The technique is based on the determination of a coinci…
View article: Optimization of Civil Servants' Performance at the Department of Population and Civil Registration, South Papua Provincial Government
Optimization of Civil Servants' Performance at the Department of Population and Civil Registration, South Papua Provincial Government Open
The main problem in our study is the Unorderly Administration of Population and Civil Registration Services at the Population and Civil Registration and Community and Village Empowerment Service of Merauke Regency. This is because South Pa…
View article: Glue and Ethanol Mixture for Aneurysm Endovascular Treatment: Animal Lab Study, Imaging, and Histopathological Findings
Glue and Ethanol Mixture for Aneurysm Endovascular Treatment: Animal Lab Study, Imaging, and Histopathological Findings Open
Background: This study aims to investigate the degree of penetration, permanence of occlusion, and vascular changes induced by a newly modified mixture of n-butyl cyanoacrylate (Glubran 2®), ethanol, and Lipidol® (GEL) in the endovascular …
View article: Glue and Ethanol Mixture for Aneurysm Endovascular Treatment: Animal Lab Study, Imaging, and Histopathological Findings
Glue and Ethanol Mixture for Aneurysm Endovascular Treatment: Animal Lab Study, Imaging, and Histopathological Findings Open
Background: The aim of this study was to investigate the degree of penetration, permanence of occlusion and vascular changes induced by a newly modified mixture of n-butyl cyanoacrylate (Glubran 2®), ethanol, and Lipidol® (GEL) in endovasc…
View article: Age at Tumor Diagnosis in 14,636 Canine Cases from the Pathology-Based UNIPI Animal Cancer Registry, Italy: One Size Doesn’t Fit All
Age at Tumor Diagnosis in 14,636 Canine Cases from the Pathology-Based UNIPI Animal Cancer Registry, Italy: One Size Doesn’t Fit All Open
Cancer is the most common cause of death in adult dogs. All dogs would benefit from early diagnosis, but there are no specific guidelines regarding the schedule of cancer screening in companion animals. The aim of this study was to retrosp…
View article: Methods and computational tools to study eukaryotic cell migration in vitro
Methods and computational tools to study eukaryotic cell migration in vitro Open
Cellular movement is essential for many vital biological functions where it plays a pivotal role both at the single cell level, such as during division or differentiation, and at the macroscopic level within tissues, where coordinated migr…
View article: A Preliminary Evaluation of the Prognostic Role of HER-2 and HER-3 Immunohistochemical Expression in Canine Melanomas
A Preliminary Evaluation of the Prognostic Role of HER-2 and HER-3 Immunohistochemical Expression in Canine Melanomas Open
Canine melanoma is a malignant and aggressive neoplasm showing clinical, histological, and molecular features similar to the human counterpart. In human medicine, epidermal growth factor receptors (EGFRs) have already been suggested as pro…
View article: Breed Predispositions and Malignancy Analysis in 26,224 Histopathologic Diagnoses of Canine Tumors: Results from a Multicenter Study in Central Italy (2008-2023)
Breed Predispositions and Malignancy Analysis in 26,224 Histopathologic Diagnoses of Canine Tumors: Results from a Multicenter Study in Central Italy (2008-2023) Open
View article: Cancerogenic parasites in veterinary medicine: a narrative literature review
Cancerogenic parasites in veterinary medicine: a narrative literature review Open
View article: Exploring the link between viruses and cancer in companion animals: a comprehensive and comparative analysis
Exploring the link between viruses and cancer in companion animals: a comprehensive and comparative analysis Open
Currently, it is estimated that 15% of human neoplasms globally are caused by infectious agents, with new evidence emerging continuously. Multiple agents have been implicated in various forms of neoplasia, with viruses as the most frequent…
View article: Plasma Human Immunodeficiency Virus 1 RNA and CD4+ T-Cell Counts Are Determinants of Virological Nonsuppression Outcomes With Initial Integrase Inhibitor-Based Regimens: A Prospective RESPOND Cohort Study
Plasma Human Immunodeficiency Virus 1 RNA and CD4+ T-Cell Counts Are Determinants of Virological Nonsuppression Outcomes With Initial Integrase Inhibitor-Based Regimens: A Prospective RESPOND Cohort Study Open
Background There are conflicting data regarding baseline determinants of virological nonsuppression outcomes in persons with human immunodeficiency virus (HIV) starting antiretroviral treatment (ART). We evaluated the impact of different b…
View article: Confirmation of the Prognostic Value of Foxp3+ Cells in Canine Mammary Tumors
Confirmation of the Prognostic Value of Foxp3+ Cells in Canine Mammary Tumors Open
Foxp3+ cell counts were evaluated by immunohistochemistry in 59 canine mammary tumors, 20 adenomas, and 39 carcinomas in three different compartments: intratumoral, within the adjacent stroma, and in the distant stroma. Foxp3+ lymphocyte c…
View article: Preliminary Assessment of Tumor-Associated Tissue Eosinophilia (TATE) in Canine Mast Cell Tumors: Prevalence and Prognostic Relevance and Its Association with Neoangiogenesis
Preliminary Assessment of Tumor-Associated Tissue Eosinophilia (TATE) in Canine Mast Cell Tumors: Prevalence and Prognostic Relevance and Its Association with Neoangiogenesis Open
Mast cell tumor (MCT) is the most common malignant skin tumor in dogs. In order to gain more information on the prognostic markers in MCT, the role of the eosinophil granulocytes infiltrates was investigated and assessed by the evaluation …
View article: Tissue changes induced by cyanoacrylate-based glues used to fix a light polyvinylidene fluoride (PVDF) mesh in a rat model
Tissue changes induced by cyanoacrylate-based glues used to fix a light polyvinylidene fluoride (PVDF) mesh in a rat model Open
For their quick action and binding strength, cyanoacrylate (CA)-based tissue adhesives can be used instead of sutures to fix meshes used for hernia repair. The current study's objective was to evaluate the tissue alterations induced by CA …
View article: Skeletal muscle dissemination in a dog with T‐cell lymphoma
Skeletal muscle dissemination in a dog with T‐cell lymphoma Open
A 5‐year‐old spayed female American Staffordshire was referred for weakness, reluctance to move and distension of the abdomen. Three weeks before, the dog underwent surgery for excision of a nodular mass suspected to be a non‐epitheliotrop…
View article: Immunohistochemical Characterization of Immune System Cells in Lymphoid Organs from Roe and Fallow Deer
Immunohistochemical Characterization of Immune System Cells in Lymphoid Organs from Roe and Fallow Deer Open
Roe and Fallow deer are common wild ruminants widely distributed in Italy. Infectious diseases of these species can potentially pose health risks to domestic animals and humans. However, few studies have been conducted in which immune syst…
View article: Occurrence of Bacterial and Protozoan Pathogens in Red Foxes (Vulpes vulpes) in Central Italy
Occurrence of Bacterial and Protozoan Pathogens in Red Foxes (Vulpes vulpes) in Central Italy Open
Most surveys of pathogens in red foxes (Vulpes vulpes) have focused on particular agents. The aim of this study was to verify, with bacteriological and molecular analyses, the occurrence of the main bacterial and protozoan pathogens that a…
View article: Skin Photodamage Lesions in a Bilateral Feline Auricular Primary Fibrosarcoma
Skin Photodamage Lesions in a Bilateral Feline Auricular Primary Fibrosarcoma Open
As with human species, recent studies also suggest a photoinduced etiopathology for non-epithelial cutaneous tumors in feline species. We report a recent case of a ten-year-old male cat with a white-hair coat and mesenchymal neoplasms of b…
View article: Toxoplasmosis in Captive Ring-Tailed Lemurs (Lemur catta)
Toxoplasmosis in Captive Ring-Tailed Lemurs (Lemur catta) Open
Toxoplasma gondii is one of the most common protozoan parasites and is widely present in all warm-blooded animals. Although clinical disease is uncommon, some species, including ring-tailed lemurs (Lemur catta), have been found to develop …
View article: Virulence Genes of Pathogenic Escherichia coli in Wild Red Foxes (Vulpes vulpes)
Virulence Genes of Pathogenic Escherichia coli in Wild Red Foxes (Vulpes vulpes) Open
Different pathotypes of Escherichia coli can cause severe diseases in animals and humans. Wildlife may contribute to the circulation of pathogenic pathotypes, including enteropathogenic E. coli (EPEC), Shiga toxin-producing E. coli (STEC),…
View article: The Italian Network of Laboratories for Veterinary Oncology (NILOV) 2.0: Improving Knowledge on Canine Tumours
The Italian Network of Laboratories for Veterinary Oncology (NILOV) 2.0: Improving Knowledge on Canine Tumours Open
Advances in tumour research are crucial, and comparative oncology can improve the knowledge in several ways. Dogs are not only models of specific naturally occurring tumours but can also be sentinels of environmental exposures to carcinoge…
View article: Presence of a mouse mammary tumour virus-like in feline lymphomas: a preliminary study
Presence of a mouse mammary tumour virus-like in feline lymphomas: a preliminary study Open
View article: Mouse Mammary Tumor Virus (MMTV) and MMTV-like Viruses: An In-depth Look at a Controversial Issue
Mouse Mammary Tumor Virus (MMTV) and MMTV-like Viruses: An In-depth Look at a Controversial Issue Open
Since its discovery as a milk factor, mouse mammary tumor virus (MMTV) has been shown to cause mammary carcinoma and lymphoma in mice. MMTV infection depends upon a viral superantigen (sag)-induced immune response and exploits the immune s…
View article: Molecular and Pathological Detection of Hepatitis E Virus in Roe Deer (Capreolus capreolus) and Fallow Deer (Dama dama) in Central Italy
Molecular and Pathological Detection of Hepatitis E Virus in Roe Deer (Capreolus capreolus) and Fallow Deer (Dama dama) in Central Italy Open
Hepatitis E virus (HEV) is a common causative agent of acute hepatitis in the world, with a serious public health burden in both developing and industrialized countries. Cervids, along with wild boars and lagomorphs, are the main wild host…
View article: Molecular Detection of Avipoxvirus in Wild Birds in Central Italy
Molecular Detection of Avipoxvirus in Wild Birds in Central Italy Open
Avipoxviruses (APVs) are important pathogens of both domestic and wild birds. The associated disease is characterized by skin proliferative lesions in the cutaneous form or by lesions of the first digestive and respiratory tracts in the di…
View article: Auricular Non-Epithelial Tumors with Solar Elastosis in Cats: A Possible UV-Induced Pathogenesis
Auricular Non-Epithelial Tumors with Solar Elastosis in Cats: A Possible UV-Induced Pathogenesis Open
The photoinduced etiopathology of actinic keratosis and squamous cell carcinoma in feline species is well known. This etiology has also been reported for non-epithelial cutaneous tumors in other species. To date, no cases of auricular non-…
View article: «Profondo inesplorabile mistero». Marianna Florenzi Waddington, Leibniz e la prima edizione italiana della Monadologia (1856)
«Profondo inesplorabile mistero». Marianna Florenzi Waddington, Leibniz e la prima edizione italiana della Monadologia (1856) Open
In 1856, the Florentine Tipografia Bencini published the first Italian version of Leibniz’s Monadology edited and translated by the Umbrian philosopher Marianna Florenzi Waddington. It is an atypical edition, not concerned with ph…
View article: Pathological Features and Molecular Phenotype of MMTV Like-Positive Feline Mammary Carcinomas
Pathological Features and Molecular Phenotype of MMTV Like-Positive Feline Mammary Carcinomas Open
In the last few years MMTV-like nucleotide sequences were detected in some feline and canine mammary tumours. Due to the confirmed role of cats in the epidemiology of the MMTV-like virus, the aim of this study was to investigate the main p…
View article: Survey on the Presence of Bacterial and Parasitic Zoonotic Agents in the Feces of Wild Birds
Survey on the Presence of Bacterial and Parasitic Zoonotic Agents in the Feces of Wild Birds Open
Wild avifauna may act as fecal source of bacterial and parasitic pathogens for other birds and mammals. Most of these pathogens have a relevant impact on human and livestock health which may cause severe disease and economic loss. In the p…
View article: An Immunohistochemical Study of the PTEN/AKT Pathway Involvement in Canine and Feline Mammary Tumors
An Immunohistochemical Study of the PTEN/AKT Pathway Involvement in Canine and Feline Mammary Tumors Open
Phosphatase and tensin homolog deleted on chromosome10 (PTEN), phospho-v-Akt murine thymoma viral oncogene homolog (AKT), and the Rapamycin-Insensitive Companion of mTOR (Rictor) expression was investigated by immunohistochemistry in 10 ca…