Explanipedia

Reintervention for recurrence of mitral valve regurgitation: Transventricular beating heart neochordae implantation versus on-pump surgery Open

Cristina Barbero, Alessandro Vairo, Matteo Marro, Claudia Filippini, C. Capozza , et al. · 2025

A Machine Learning Approach to Predict Successful Trans-Ventricular Off-Pump Micro-Invasive Mitral Valve Repair Open

Alessandro Vairo, Caterina Russo, Andrea Saglietto, R Cimino, Marco Pocar , et al. · 2025

Background: The NeoChord procedure is a trans-ventricular, echo-guided, beating-heart mitral valve (MV) repair technique used to treat degenerative mitral regurgitation (MR) caused by leaflet prolapse and/or flail. Objectives: This study a…

Geometric ring aortic valve repair in tetralogy of Fallot: First reported case Open

Marco Pocar, Giacomo Maraschioni, Cristina Barbero, Stefano Salizzoni, Alessandro Vairo , et al. · 2024

A COMPLEX CASE OF EARLY ONSET ATRIAL FIBRILLATION IN AN ENDURANCE ATHLETE: THE IMPORTANCE OF FAMILY HISTORY Open

A. Solano, L. Tallone, E Bertello, P Berruquier, Andrea Saglietto , et al. · 2024

Introduction Early onset atrial fibrillation (AF) in an endurance athlete represents a challenge for the cardiologist, especially in apparent absence of an overt structural heart disease. Different genetic variants have been associated wit…

SPORT INDUCED QT PROLONGATION: DETECTION AND MANAGEMENT OF THIS NEW COMPLEX ENTITY Open

Edoardo Roagna, A Visalli, Anna Tribuzio, A Saglietto, Alessandro Vairo , et al. · 2024

Introduction Intense exercise training has been recently associated with QTc prolongation and morphologic repolarization abnormalities, whereas detraining, in asymptomatic genotype negative patients, was associated with ECG normalization. …

ACQUIRED LQTS WITH VENTRICULAR ARRHYTMIAS IN METHADONE AND CARDIOMYOPATHY AT ONSET Open

Edoardo Roagna, Filippo Angelini, Guglielmo Gallone, Alessandro Vairo, Matteo Bellettini , et al. · 2024

Introduction Methadone is associated with QT interval prolongation and increased risk of ventricular arrhythmias such as torsade de pointes (TdP), particularly if associated with other contributing factors. The management is complex, consi…

CLINICAL AND GENETIC FEATURES OF JUVENILE ONSET LONE ATRIAL FIBRILLATION Open

E Bertello, P Berruquier, Veronica Dusi, Andrea Saglietto, Cristina Vallino , et al. · 2024

Background Juvenile–onset lone atrial fibrillation (LAF) may be the initial manifestation of an othrewise concealed channelopathy or cardiomyopathy (CMP). Clinical characteristics, genetic background and proper management are still largely…

Transcatheter Mitral Valve Implantation in Failed Transventricular Mitral Valve Repair Open

Giulia Agostini, Alessandro Vairo, Antonio Montefusco, Matteo Marro, Andrea Costamagna , et al. · 2024

Arrhythmic risk profile in mitral valve prolapse: A systematic review and metanalysis of 1715 patients Open

Lorenzo Pistelli, Giampaolo Vetta, Antonio Parlavecchio, Pasquale Crea, Francesca Parisi , et al. · 2023

Introduction Mitral valve prolapse (MVP) is a common clinical condition in the general population. A subgroup of patients with MVP may experience ventricular arrhythmias and sudden cardiac death (“arrhythmic mitral valve prolapse” [AMVP]) …

Minimally Invasive Surgery: Standard of Care for Mitral Valve Endocarditis Open

Cristina Barbero, Marco Pocar, Dario Brenna, Barbara Parrella, Sara Baldarelli , et al. · 2023

Background. Minimally invasive surgery via right mini-thoracotomy has become the standard of care for the treatment of mitral valve disease worldwide, particularly at high-volume centers. In recent years, the spectrum of indications has pr…

Minimally Invasive Surgery: Standard of Care for Mitral Valve Endocarditis Open

Cristina Barbero, Marco Pocar, Dario Brenna, Barbara Parrella, Sara Baldarelli , et al. · 2023

Background. Minimally invasive surgery via right mini-thoracotomy has become the standard of care for the treatment of mitral valve disease worldwide, particularly at high volume centers. In recent years, the spectrum of indications has pr…

Acute modification of hemodynamic forces in patients with severe aortic stenosis after transcatheter aortic valve replacement Open

L Zaccaro, Alessandro Vairo, Gianluca Alunni, F. D’Ascenzo, Gaetano Maria De Ferrari · 2023

Funding Acknowledgements Type of funding sources: None. Background Transcatheter-Aortic-Valve-Implantation (TAVI) is the established first-line treatment for patient with severe aortic stenosis not suitable for surgery. Echocardiographic e…

Left atrial function assessed by speckle tracking echocardiography as a marker of atrial reverse remodeling in patients with mitral regurgitation treated with transcatheter edge-to-edge repair Open

Stefano Avondo, Luca Arzuffi, Jessica Zannoni, Alessandro Vairo, Fabrizio D’Ascenzo , et al. · 2023

Funding Acknowledgements Type of funding sources: None. Background Left atrial reverse remodeling has been defined relying on changes in left atrial volume following specific procedures. Little is known about functional assessment of the l…

New insights into the correlation between genotype and cardiac phenotype in laminopathies Open

Veronica Dusi, Filippo Angelini, S. Elia, S Pidello, Alessandro Vairo , et al. · 2023

Funding Acknowledgements Type of funding sources: None. Background Genotype-phenotype correlation and risk stratification for heart failure progression in patients with cardiolaminopathies are poorly defined. Purpose The primary aim of the…

Impact of cardiac sympathetic denervation on electrical storms in patients with cardiomyopathies Open

Veronica Dusi, Marta Ruffinazzi, Luigi Pugliese, Francesco Guerrera, Alessandro Vicentini , et al. · 2023

Funding Acknowledgements Type of funding sources: None. Background Cardiac Sympathetic Denervation (CSD) has been recently proposed for the treatment of refractory ventricular arrhythmias (VAs) in patients with cardiomyopathy (CMP). A mult…

C3 OUTCOME OF CARDIAC SYMPATHETIC DENERVATION IN CARDIOMYOPATHIES AND PREDICTORS OF RECURRENCES Open

Veronica Dusi, Marta Ruffinazzi, Luigi Pugliese, Francesco Guerrera, Enrico Baldi , et al. · 2023

Background Cardiac Sympathetic Denervation (CSD) has been recently proposed for the treatment of refractory ventricular arrhythmias (VAs) in patients with cardiomyopathy (CMP). Long–term outcome and predictors of recurrences after the proc…

The r’-Wave Algorithm: A New Diagnostic Tool to Predict the Diagnosis of Brugada Syndrome after a Sodium Channel Blocker Provocation Test Open

Giampaolo Vetta, Antonio Parlavecchio, Lorenzo Pistelli, Paolo Desalvo, Armando Lo Savio , et al. · 2023

A diagnosis of Brugada syndrome (BrS) is based on the presence of a type 1 electrocardiogram (ECG) pattern, either spontaneously or after a Sodium Channel Blocker Provocation Test (SCBPT). Several ECG criteria have been evaluated as predic…

New Echocardiographic Parameters Predicting Successful Trans-Ventricular Beating-Heart Mitral Valve Repair with Neochordae at 3 Years: Monocentric Retrospective Study Open

Alessandro Vairo, Lorenzo Gaiero, Matteo Marro, Caterina Russo, Marco Bolognesi , et al. · 2023

The NeoChord procedure is an echo-guided trans-ventricular beating-heart mitral valve repair technique to treat degenerative mitral regurgitation (MR) due to prolapse and/or flail. The aim of this study is to analyze echocardiographic imag…

Acute Modification of Hemodynamic Forces in Patients with Severe Aortic Stenosis after Transcatheter Aortic Valve Implantation Open

Alessandro Vairo, Lorenzo Zaccaro, Andrea Ballatore, Lorenzo Airale, Fabrizio D’Ascenzo , et al. · 2023

Transcatheter aortic valve implantation (TAVI) is the established first-line treatment for patient with severe aortic stenosis not suitable for surgery. Echocardiographic evaluation of hemodynamic forces (HDFs) is a growing field, holding …

Echocardiographic Parameters to Predict Malignant Events in Arrhythmic Mitral Valve Prolapse Population Open

Alessandro Vairo, Paolo Desalvo, Andrea Rinaudo, Francesco Piroli, Anna Tribuzio , et al. · 2023

Bileaflet Mitral Valve Prolapse (bMVP) has been linked to major arrhythmic events and sudden cardiac death (SCD). Consistent predictors in this field are still lacking. Echocardiography is the best tool for the analysis of the prolapse and…

958 IMPACT OF CARDIAC SYMPATHETIC DENERVATION ON ELECTRICAL STORMS IN PATIENTS WITH CARDIOMIOPATHIES Open

Veronica Dusi, Luigi Pugliese, Marta Ruffinazzi, Francesco Guerrera, Antonio Sanzo , et al. · 2022

Background Cardiac Sympathetic Denervation (CSD) has been recently proposed for the treatment of refractory ventricular arrhythmias (VAs) in patients with cardiomyopathy (CMP). A multicentric American and Indian case series suggested a gre…

Successful Percutaneous Retrieval of an Embolized Left Atrial Appendage Occluder Open

Federico Ferraris, M Millesimo, Matteo Anselmino, Davide Castagno, Alessandro Vairo , et al. · 2022

P102 NEW THREE–DIMENSIONAL ECHOCARDIOGRAPHIC PREDICTING PARAMETERS IN TRANS–VENTRICULAR HEART–BEATING MITRAL VALVE REPAIR WITH NEOCHORDAE: A MONOCENTRIC RETROSPECTIVE STUDY Open

Lorenzo Gaiero, Alessandro Vairo, Francesco Fioravanti, Francesco Piroli, Guglielmo Gallone , et al. · 2022

Background Trans–ventricular off pump mitral valve (MV) repair with neochordae implantation (Neochord procedure) is a minimally invasive surgical technique for correction of degenerative mitral regurgitation (MR) due to prolapse or flail. …

C40 THREE–DIMENSIONAL FINGER TEST: A NEW ECHOCARDIOGRAPHIC METHOD TO LOCATE THE BEST ACCESS SITE DURING NEOCHORD PROCEDURE Open

Alessandro Vairo, Gianluca Alunni, L Franchin, Federico Fortuni, L Gaiero , et al. · 2022

Background The NeoChord procedure is a trans–ventricular, beating–heart chordal implantation for severe degenerative mitral valve regurgitation due to prolapse or flail leaflet and it is performed using a dedicated device (DS 1000 system, …

Clinical outcomes following isolated transcatheter tricuspid valve repair: a meta-analysis and meta-regression study Open

Pier Paolo Bocchino, Filippo Angelini, Alessandro Vairo, Alessandro Andreis, Federico Fortuni , et al. · 2021

Background Significant tricuspid regurgitation (TR) is a common valvular heart disease worldwide. Purpose We aimed to assess the pooled clinical and echocardiographic outcomes of different isolated transcatheter tricuspid valve repair (ITT…

Valve-in-Valve-in-Ring Open

Alessandro Vairo, Federico De Marco, Luca Franchin, Federico Fortuni, Francesco Bruno , et al. · 2021

A 55-year-old male with a history of severe organic mitral regurgitation treated with surgical mitral valve (MV) repair was referred for a transcatheter MV replacement due to recurrent regurgitation. After the release of the first transcat…

The Neochord Procedure After Failed Surgical Mitral Valve Repair Open

Gino Gerosa, Laura Besola, Andrés Beiras-Fernández, Stefano Salizzoni, Alessandro Vairo , et al. · 2020

In the midst of a dangerous intersection with unclear therapeutic strategies: a challenging case of severe aortic stenosis Open

Guglielmo Gallone, Federico Landra, Fabrizio D’Ascenzo, Federico Conrotto, R Casoni , et al. · 2020

P1412 A new light to improve the view of the anatomical details during micro-invasive trans-ventricular repair of degenerative prolapse of mitral valve Open

Alessandro Vairo, Matteo Marro, Giovanni Speziali, M Rinaldi, Stefano Salizzoni · 2020

BACKGROUND Mitral valve repair is the preferred surgical treatment for severe mitral regurgitation due to degenerative leaflet prolapse. Within the growing era of transcatheter treatments for valvular heart disease, an innovative micro-inv…

Subclinical left ventricular dysfunction in severe obesity and reverse cardiac remodeling after bariatric surgery Open

Vittoria Scarlatta, Simone Frea, Alessandro Andreis, Chiara Rovera, Alessandro Vairo , et al. · 2020

Obese patients candidate to bariatric surgery have an high prevalence of preclinical SD and LVH/CR, early detectable with echocardiography. Bariatric surgery is associated with reverse cardiac remodeling; it might also have a preventive ef…

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