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View article: Core Symptoms of Eating Disorders and Heart Rate Variability: A Systematic Review
Core Symptoms of Eating Disorders and Heart Rate Variability: A Systematic Review Open
(1) Eating disorders (EDs), characterized by symptoms such as restrictive eating, binge eating, compensatory behaviors, and emotional dysregulation, are associated with autonomic nervous system dysregulation, which may contribute to cardio…
View article: Cognitive Correlates of Functional Disruption at Psychosis Onset: Unique Relevance of Visual Cognition
Cognitive Correlates of Functional Disruption at Psychosis Onset: Unique Relevance of Visual Cognition Open
Background: Cognitive impairment is a common feature of schizophrenia spectrum disorders and has been associated with functional disruption preceding the onset of psychosis. Understanding how cognitive deficits interact with clinical sympt…
View article: Longitudinal changes in DNA methylation associated with clozapine use in treatment-resistant schizophrenia from two international cohorts
Longitudinal changes in DNA methylation associated with clozapine use in treatment-resistant schizophrenia from two international cohorts Open
View article: Systematic Review of Computerised Cognitive Remediation interventions in Early Psychosis: Do we Still Need “Somebody with a Human Touch”?
Systematic Review of Computerised Cognitive Remediation interventions in Early Psychosis: Do we Still Need “Somebody with a Human Touch”? Open
Purpose of the Review Several computerized cognitive remediation (CCR) programs have been developed in recent years, although their efficacy in First Episode Psychosis (FEP) remains unclear, particularly regarding the benefits in terms of …
View article: Do Cognitive Subtypes Exist in People at Clinical High Risk for Psychosis? Results From the EU-GEI Study
Do Cognitive Subtypes Exist in People at Clinical High Risk for Psychosis? Results From the EU-GEI Study Open
Background and Hypothesis Cognition has been associated with socio-occupational functioning in individuals at Clinical High Risk for Psychosis (CHR-P). The present study hypothesized that clustering CHR-P participants based on cognitive da…
View article: Longitudinal changes in DNA methylation associated with clozapine use in treatment-resistant schizophrenia from two international cohorts
Longitudinal changes in DNA methylation associated with clozapine use in treatment-resistant schizophrenia from two international cohorts Open
The second-generation antipsychotic clozapine is used as a medication for treatment-resistant schizophrenia. It has previously been associated with epigenetic changes in pre-clinical rodent models and cross-sectional studies of treatment-r…
View article: Subcortical volume reduction and cortical thinning 3 months after switching to clozapine in treatment resistant schizophrenia
Subcortical volume reduction and cortical thinning 3 months after switching to clozapine in treatment resistant schizophrenia Open
View article: Changes in Brain Glutamate on Switching to Clozapine in Treatment-Resistant Schizophrenia
Changes in Brain Glutamate on Switching to Clozapine in Treatment-Resistant Schizophrenia Open
It has been suggested that the antipsychotic clozapine may modulate brain glutamate, and that this effect could contribute to its efficacy in treatment-resistant schizophrenia (TRS). The aim of this study was to examine the effects of cloz…
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Authors' reply Open
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View article: Disorder, not just state of risk: Meta-analysis of functioning and quality of life in people at high risk of psychosis
Disorder, not just state of risk: Meta-analysis of functioning and quality of life in people at high risk of psychosis Open
Background The nosology of the psychosis high-risk state is controversial. Traditionally conceived as an ‘at risk’ state for the development of psychotic disorders, it is also conceptualised as a clinical syndrome associated with functiona…
View article: Meta-analysis of Quality of Life Data in Subjects at High Risk for Psychosis.
Meta-analysis of Quality of Life Data in Subjects at High Risk for Psychosis. Open
The nosology of the psychosis high-risk (HR) state is highly controversial. Traditionally conceived as an 'at-risk" state for the development of psychotic disorders, it is also conceptualized as a clinical syndrome associated with function…