Alex D. Michaels
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View article: Figure S1 from CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer
Figure S1 from CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer Open
Supplementary Figure S1. Macrophage depletion following clodronate treatment. Flow cytometry dot-plots of athymic nude mouse whole-liver digests at days 2, 8, and 12 following splenic injection of T608 patient-derived pancreatic ductal ade…
View article: Data from CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer
Data from CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer Open
Purpose: Patients with pancreatic ductal adenocarcinoma (PDAC) who undergo surgical resection and adjuvant chemotherapy have an expected survival of only 2 years due to disease recurrence, frequently in the liver. We investigated th…
View article: Data from CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer
Data from CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer Open
Purpose: Patients with pancreatic ductal adenocarcinoma (PDAC) who undergo surgical resection and adjuvant chemotherapy have an expected survival of only 2 years due to disease recurrence, frequently in the liver. We investigated th…
View article: Figure S1 from CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer
Figure S1 from CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer Open
Supplementary Figure S1. Macrophage depletion following clodronate treatment. Flow cytometry dot-plots of athymic nude mouse whole-liver digests at days 2, 8, and 12 following splenic injection of T608 patient-derived pancreatic ductal ade…
View article: Supplemental legend from CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer
Supplemental legend from CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer Open
Supplemental legend
View article: Supplemental legend from CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer
Supplemental legend from CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer Open
Supplemental legend
View article: Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth
Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth Open
Mitochondria undergo fission and fusion to maintain homeostasis, and tumors exhibit the dysregulation of mitochondrial dynamics. We recently demonstrated that ectopic HRasG12V promotes mitochondrial fragmentation and tumor growt…
View article: CRISPR knockout screening identifies combinatorial drug targets in pancreatic cancer and models cellular drug response
CRISPR knockout screening identifies combinatorial drug targets in pancreatic cancer and models cellular drug response Open
View article: Race is associated with completion of neoadjuvant chemotherapy for breast cancer
Race is associated with completion of neoadjuvant chemotherapy for breast cancer Open
View article: CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer
CD47 Blockade as an Adjuvant Immunotherapy for Resectable Pancreatic Cancer Open
Purpose: Patients with pancreatic ductal adenocarcinoma (PDAC) who undergo surgical resection and adjuvant chemotherapy have an expected survival of only 2 years due to disease recurrence, frequently in the liver. We investigated the role …
View article: Henry Ford HEART Score Randomized Trial
Henry Ford HEART Score Randomized Trial Open
Background— Hospital evaluation of patients with chest pain is common and costly. The HEART score risk stratification tool that merges troponin testing into a clinical risk model for evaluation emergency department patients with possible a…
View article: Unplanned Reoperation Following Colorectal Surgery: Indications and Operations
Unplanned Reoperation Following Colorectal Surgery: Indications and Operations Open
View article: Hypoglycemia Following Bariatric Surgery: Our 31-Year Experience
Hypoglycemia Following Bariatric Surgery: Our 31-Year Experience Open
View article: Risk Associated With Complications and Mortality After Urgent Surgery vs Elective and Emergency Surgery
Risk Associated With Complications and Mortality After Urgent Surgery vs Elective and Emergency Surgery Open
This study highlights the need for improved risk stratification on the basis of urgency because operations performed urgently have distinct rates of morbidity and mortality compared with procedures performed either electively or emergently…
View article: Patient travel for bariatric surgery: does distance matter?
Patient travel for bariatric surgery: does distance matter? Open
View article: The role of liver-directed surgery in patients with hepatic metastasis from primary breast cancer: a multi-institutional analysis
The role of liver-directed surgery in patients with hepatic metastasis from primary breast cancer: a multi-institutional analysis Open
View article: Declining Operative Experience for Junior-Level Residents: Is This an Unintended Consequence of Minimally Invasive Surgery?
Declining Operative Experience for Junior-Level Residents: Is This an Unintended Consequence of Minimally Invasive Surgery? Open
View article: Ileal J-Pouch Volvulus Following Total Proctocolectomy for Ulcerative Colitis
Ileal J-Pouch Volvulus Following Total Proctocolectomy for Ulcerative Colitis Open
View article: Risk Factors for Urinary Tract Infections in Cardiac Surgical Patients
Risk Factors for Urinary Tract Infections in Cardiac Surgical Patients Open
There are several identifiable risk factors for CAUTI in patients undergoing cardiac procedures. CAUTI is not independently associated with increased mortality, but it does serve as a marker of sicker patients more likely to die from other…