Alex Förster
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View article: Longitudinal automated brain volumetry versus expert visual assessment of atrophy progression on MRI: an exploratory study
Longitudinal automated brain volumetry versus expert visual assessment of atrophy progression on MRI: an exploratory study Open
Automated tools have been proposed to quantify brain volume for suspected dementia diagnoses. However, their robustness in longitudinal, real-life cohorts remains unexplored. This exploratory study examined if expert visual assessment (EVA…
View article: Longitudinal automated brain volumetry vs. expert visual assessment of atrophy progression on MRI is robust but caution is advised
Longitudinal automated brain volumetry vs. expert visual assessment of atrophy progression on MRI is robust but caution is advised Open
Automated tools have been proposed to quantify brain volume for suspected dementia diagnoses. However, their robustness in longitudinal, real-life cohorts remains unexplored. We investigated if expert visual assessment (EVA) of atrophy pro…
View article: Diffusion Restricted Lesions in the Splenium of the Corpus Callosum
Diffusion Restricted Lesions in the Splenium of the Corpus Callosum Open
Diffusion restricted lesions in the splenium of the CC are best classified by localization, shape, and size, whereas relative ADC values are of limited value for differentiation of different neurological disorders.
View article: Artificial Neural Network-Derived Cerebral Metabolic Rate of Oxygen for Differentiating Glioblastoma and Brain Metastasis in MRI: A Feasibility Study
Artificial Neural Network-Derived Cerebral Metabolic Rate of Oxygen for Differentiating Glioblastoma and Brain Metastasis in MRI: A Feasibility Study Open
Glioblastoma may appear similar to cerebral metastasis on conventional MRI in some cases, but their therapies differ significantly. This prospective feasibility study was aimed at differentiating them by applying the quantitative susceptib…
View article: MRI topography of lesions related to internuclear ophthalmoplegia in patients with multiple sclerosis or ischemic stroke
MRI topography of lesions related to internuclear ophthalmoplegia in patients with multiple sclerosis or ischemic stroke Open
Background and Purpose Internuclear ophthalmoplegia is a dysfunction of conjugate eye movements, caused by lesions affecting the medial longitudinal fasciculus (MLF). Multiple sclerosis (MS) and ischemic stroke represent the most common pa…
View article: Crossed Cerebellar Diaschisis in Alzheimer’s Disease Detected by Arterial Spin-labelling Perfusion MRI
Crossed Cerebellar Diaschisis in Alzheimer’s Disease Detected by Arterial Spin-labelling Perfusion MRI Open
It was possible to detect CCD by ASL PWI in approximately one-third of patients with AD and was associated with smaller whole brain and white matter volume.
View article: Intrinsic photogeneration of long-lived charges in a donor-orthogonal acceptor conjugated polymer
Intrinsic photogeneration of long-lived charges in a donor-orthogonal acceptor conjugated polymer Open
The spatial separation ofPCPDT-sFCN's donor and orthogonal acceptor motifs allows efficient photogeneration of extraordinarily long-lived charge carriers in the pristine polymer, providing an important step towards single-material optoelec…
View article: Fulminant Cytotoxic Edema in a Patient with Pneumococcal Meningoencephalitis
Fulminant Cytotoxic Edema in a Patient with Pneumococcal Meningoencephalitis Open
A 37-year-old male patient was admitted to the emergency room 3 days after last being seen well.He had been found in his apartment at a reduced level of consciousness, with foam in his mouth and enuresis.His tympanic temperature was 40°C.T…
View article: P05.35 Intraoperative radiotherapy after resection of brain metastases (INTRAMET) - initial safety/efficacy analysis of a prospective phase II study
P05.35 Intraoperative radiotherapy after resection of brain metastases (INTRAMET) - initial safety/efficacy analysis of a prospective phase II study Open
Brain metastases occur in roughly 40% of patients diagnosed with systemic cancer. External beam radiotherapy (to the cavity or whole brain) lowers local recurrence rates but also prolongs the time to (systemic) salvage therapies. We here p…
View article: Contrast-enhanced fat-suppressed FLAIR for the characterization of leptomeningeal inflammation in optic neuritis
Contrast-enhanced fat-suppressed FLAIR for the characterization of leptomeningeal inflammation in optic neuritis Open
Background: Leptomeningeal contrast enhancement on fluid-attenuated inversion recovery (FLAIR) images has been reported in patients with multiple sclerosis and interpreted as a biomarker of inflammation. In this study, we sought to evaluat…
View article: Anatomical distribution of cerebral microbleeds and intracerebral hemorrhage in vertebrobasilar dolichoectasia
Anatomical distribution of cerebral microbleeds and intracerebral hemorrhage in vertebrobasilar dolichoectasia Open
cMBs and ICH may be observed in the anterior and posterior circulation in VBD but they occur more frequently in the posterior circulation. Most common anatomical locations of cMBs in VBD were the thalamus, occipital lobe and cerebellum. Th…
View article: Separating Symptomatic Alzheimer’s Disease from Depression based on Structural MRI
Separating Symptomatic Alzheimer’s Disease from Depression based on Structural MRI Open
Older patients with depression or Alzheimer's disease (AD) at the stage of early dementia or mild cognitive impairment may present with objective cognitive impairment, although the pathology and thus therapy and prognosis differ substantia…
View article: Susceptibility Vessel Sign on T2*-Weighted Gradient Echo Imaging in Lacunar Infarction
Susceptibility Vessel Sign on T2*-Weighted Gradient Echo Imaging in Lacunar Infarction Open
SVS on GRE may be useful for detection of perforating artery occlusion in a subset of patients with hyperacute LI.
View article: Objective Comparison Using Guideline-based Query of Conventional Radiological Reports and Structured Reports
Objective Comparison Using Guideline-based Query of Conventional Radiological Reports and Structured Reports Open
Objective guideline-based comparison of SRs and cFTRs using the CSS is feasible and provides a scalable quality measure that can facilitate the adoption of structured reports in all fields of radiology.
View article: NIMG-56. CHARACTERISTIC RESPONSE PATTERNS IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA AFTER TREATMENT WITH HIGH SINGLE DOSES OF RADIOTHERAPY
NIMG-56. CHARACTERISTIC RESPONSE PATTERNS IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA AFTER TREATMENT WITH HIGH SINGLE DOSES OF RADIOTHERAPY Open
BACKGROUND: Healthy brain tissue responses to radiotherapy (pseudoprogression/radiation necrosis) may bias MRI-based tumor response evaluations. To understand these changes specifically after high doses of radiotherapy, we analyzed MRIs of…
View article: Combination of standard axial and thin‐section coronal diffusion‐weighted imaging facilitates the diagnosis of brainstem infarction
Combination of standard axial and thin‐section coronal diffusion‐weighted imaging facilitates the diagnosis of brainstem infarction Open
Background and Purpose Although diffusion‐weighted imaging ( DWI ) is a very sensitive technique for the detection of small ischemic lesions in the human brain, in particular in the brainstem it may fail to demonstrate acute ischemic infar…
View article: FLAIR vascular hyperintensities and 4D MR angiograms for the estimation of collateral blood flow in anterior cerebral artery ischemia
FLAIR vascular hyperintensities and 4D MR angiograms for the estimation of collateral blood flow in anterior cerebral artery ischemia Open
FVH and flow patterns on 4D MR angiograms are markers of perfusion deficits and tissue at risk. As both methods did not show a correlation between each other, they seem to provide complimentary instead of redundant information. Previously …
View article: Incidence, Locations, and Longitudinal Course of Cerebral Microbleeds in European Moyamoya
Incidence, Locations, and Longitudinal Course of Cerebral Microbleeds in European Moyamoya Open
Background and Purpose— Cerebral microbleeds (cMBs) have previously been linked with especially high incidence in Asian patients with moyamoya together with high tendency to bleed. This, presumably, is characteristic of patients with moyam…
View article: Hyperintense Acute Reperfusion Marker on FLAIR in Posterior Circulation Infarction
Hyperintense Acute Reperfusion Marker on FLAIR in Posterior Circulation Infarction Open
HARM is a frequent finding in posterior circulation infarction and associated with vessel recanalization, minor infarction growth as well as smaller infarction volumes in the course. Neuroradiologists should be cognizant of the fact that H…
View article: Hyperintense Acute Reperfusion Marker on FLAIR in a Patient with Transient Ischemic Attack
Hyperintense Acute Reperfusion Marker on FLAIR in a Patient with Transient Ischemic Attack Open
The hyperintense acute reperfusion marker (HARM) has initially been described in acute ischemic stroke. The phenomenon is caused by blood-brain barrier disruption following acute reperfusion and consecutive delayed gadolinium enhancement i…
View article: Intra-individual diagnostic image quality and organ-specific-radiation dose comparison between spiral cCT with iterative image reconstruction and z-axis automated tube current modulation and sequential cCT
Intra-individual diagnostic image quality and organ-specific-radiation dose comparison between spiral cCT with iterative image reconstruction and z-axis automated tube current modulation and sequential cCT Open
Spiral cCT combined with ATCM and IR allows for significant-radiation dose reduction including a reduce eye lens organ-dose when compared to a tilted sequential cCT while improving subjective and objective image quality.