Adrienne Hughes
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View article: Exploring Pharmaceutical Industry Professionals’ Views and Experiences of Implementing Anonymisation for Data Sharing: A Qualitative Interview Study
Exploring Pharmaceutical Industry Professionals’ Views and Experiences of Implementing Anonymisation for Data Sharing: A Qualitative Interview Study Open
View article: Disparities in Treatment and Referral After an Opioid Overdose Among Emergency Department Patients
Disparities in Treatment and Referral After an Opioid Overdose Among Emergency Department Patients Open
Importance There is a disproportionately high rate of overdose deaths immediately following an emergency department (ED) visit for opioid overdose. Thus, an improved understanding of disparities in ED treatment and referral is vital. Racia…
View article: Heroin or fentanyl: Prevalence of confirmed fentanyl in ED patients with suspected heroin overdose
Heroin or fentanyl: Prevalence of confirmed fentanyl in ED patients with suspected heroin overdose Open
View article: A systematic evaluation of physical activity and diet policies in Scotland: results from the 2021 Active Healthy Kids Report Card
A systematic evaluation of physical activity and diet policies in Scotland: results from the 2021 Active Healthy Kids Report Card Open
Background Policymaking regarding physical activity (PA) and diet plays an important role in childhood health promotion. This study provides a detailed examination of Scottish government and policy for child and adolescent PA and diet and …
View article: O.4.6-5 Evaluation of physical activity policies in Scotland: results from the 2021 Active Healthy Kids Scotland Report Card
O.4.6-5 Evaluation of physical activity policies in Scotland: results from the 2021 Active Healthy Kids Scotland Report Card Open
Purpose The benefits of physical activity (PA) are well established for children and adolescents, and national policies can play an important role in increasing child and adolescent PA. As part of the Active Healthy Kids Global Alliance in…
View article: Opioid overdoses involving xylazine in emergency department patients: a multicenter study
Opioid overdoses involving xylazine in emergency department patients: a multicenter study Open
In this large multicenter cohort, cardiac arrest and coma in emergency department patients with illicit opioid overdose were significantly less severe in those testing positive for xylazine.
View article: Changes in Suicidal Ingestion Among Preadolescent Children From 2000 to 2020
Changes in Suicidal Ingestion Among Preadolescent Children From 2000 to 2020 Open
This cross-sectional study examines the rates of intentional misuse of substances in US children aged 6 to 18 years in the past 20 years.
View article: Impact of Physical Activity on Adiposity and Risk Markers for Cardiovascular and Metabolic Disease
Impact of Physical Activity on Adiposity and Risk Markers for Cardiovascular and Metabolic Disease Open
The main aim of the present study was to investigate the impact of physical activity (PA) on adiposity and for cardiovascular and metabolic disease risk markers (CMDRMs). In total, 55 adults (33 lean [L] and 22 overweight/obesity [O/O]) vi…
View article: Failure to Launch: Predictors of Unfavourable Physical Activity and Sedentary Behaviour Trajectories from Childhood to Adolescence: The Gateshead Millennium Study
Failure to Launch: Predictors of Unfavourable Physical Activity and Sedentary Behaviour Trajectories from Childhood to Adolescence: The Gateshead Millennium Study Open
In a previous study based on this cohort, only 15% of the participants belonged to a favourable physical activity/sedentary behaviour trajectory group (characterised by relatively high moderate–vigorous intensity physical activity and rela…
View article: <i>Notes from the Field</i>: Illicit Benzodiazepines Detected in Patients Evaluated in Emergency Departments for Suspected Opioid Overdose — Four States, October 6, 2020–March 9, 2021
<i>Notes from the Field</i>: Illicit Benzodiazepines Detected in Patients Evaluated in Emergency Departments for Suspected Opioid Overdose — Four States, October 6, 2020–March 9, 2021 Open
View article: Moderate-To-Vigorous Intensity Physical Activity and Sedentary Behaviour across Childhood and Adolescence, and Their Combined Relationship with Obesity Risk: A Multi-Trajectory Analysis
Moderate-To-Vigorous Intensity Physical Activity and Sedentary Behaviour across Childhood and Adolescence, and Their Combined Relationship with Obesity Risk: A Multi-Trajectory Analysis Open
The combined role of objectively assessed moderate-vigorous intensity physical activity (MVPA) and sedentary behaviour (SB) is unclear in obesity prevention. This study aimed to identify latent groups for MVPA and SB trajectories from chil…
View article: Variation in heart rate after acute cannabis exposure
Variation in heart rate after acute cannabis exposure Open
Smoking botanical cannabis often produces tachycardia. However, infrequent reports describe bradycardia, particularly with edibles, concentrates, and resins. We compared the rate of tachycardia in patients with acute cannabis exposures fro…
View article: Trends in socioeconomic inequalities in underweight and obesity in 5-year-old children, 2011–2018: a population-based, repeated cross-sectional study
Trends in socioeconomic inequalities in underweight and obesity in 5-year-old children, 2011–2018: a population-based, repeated cross-sectional study Open
Objective To explore trends in prevalence and socioeconomic inequalities in underweight and obesity in 5-year-old schoolchildren in Scotland between 2011/2012 and 2017/2018. Design A population-based, repeated cross-sectional study. Settin…
View article: Re-Shaping the Policy Landscape in Scottish Education, 2016-20: The Limitations of Structural Reform
Re-Shaping the Policy Landscape in Scottish Education, 2016-20: The Limitations of Structural Reform Open
This paper examines the establishment and operation of a number of new bodies – variously called councils, boards, collaboratives, groups, forums and panels – concerned with the development of Scottish education. What were the intentions b…
View article: Obesity in young children and its relationship with diagnosis of asthma, vitamin D deficiency, iron deficiency, specific allergies and flat‐footedness: A systematic review and meta‐analysis
Obesity in young children and its relationship with diagnosis of asthma, vitamin D deficiency, iron deficiency, specific allergies and flat‐footedness: A systematic review and meta‐analysis Open
Summary There is evidence that a number of medical conditions and co‐morbidities are associated with obesity in young children. This review explored whether there is evidence of associations with other conditions or co‐morbidities. Observa…
View article: Healthy Habits, Happy Homes Scotland (4HS) feasibility study: Translation of a home-based early childhood obesity prevention intervention evaluated using RE-AIM framework
Healthy Habits, Happy Homes Scotland (4HS) feasibility study: Translation of a home-based early childhood obesity prevention intervention evaluated using RE-AIM framework Open
View article: Flualprazolam: Report of an Outbreak of a New Psychoactive Substance in Adolescents
Flualprazolam: Report of an Outbreak of a New Psychoactive Substance in Adolescents Open
Flualprazolam is a nonregistered drug in the benzodiazepine family and constitutes a new psychoactive substance (NPS). Since 2014, a growing number of designer benzodiazepines have become available over the Internet and on the counterfeit …
View article: Procedures and Challenges of Adapting an Existing Public Health Intervention for Use in Another Setting: The ToyBox-Scotland Preschool Obesity Prevention Program
Procedures and Challenges of Adapting an Existing Public Health Intervention for Use in Another Setting: The ToyBox-Scotland Preschool Obesity Prevention Program Open
Childhood obesity is a major public health issue, which is reflected in the high number of interventions which have been developed to target the behaviors which cause obesity in childhood such as a lack of physical activity, poor diet, and…
View article: GRADE-ADOLOPMENT Process to Develop 24-Hour Movement Behavior Recommendations and Physical Activity Guidelines for the Under 5s in the United Kingdom, 2019
GRADE-ADOLOPMENT Process to Develop 24-Hour Movement Behavior Recommendations and Physical Activity Guidelines for the Under 5s in the United Kingdom, 2019 Open
Background : This article summarizes the approach taken to develop UK Chief Medical Officers’ physical activity guidelines for the Under 5s, 2019. Methods : The Grading of Recommendations Assessment, Development and Evaluation (GRADE)-Adap…
View article: Assessing the acceptability of an adapted preschool obesity prevention programme: ToyBox‐Scotland
Assessing the acceptability of an adapted preschool obesity prevention programme: ToyBox‐Scotland Open
Background Childhood obesity is a global public health issue. Interventions to prevent the onset of obesity in the early years are often implemented in preschool settings. The ToyBox intervention was delivered across Europe and targeted en…
View article: A feasibility cluster randomised controlled trial of a preschool obesity prevention intervention: ToyBox-Scotland
A feasibility cluster randomised controlled trial of a preschool obesity prevention intervention: ToyBox-Scotland Open
Background High levels of childhood obesity have been observed globally over the last three decades. Preschools are promising settings to implement obesity prevention interventions in the early years. The aim of this study was to test the …
View article: Associations of screen time, sedentary time and physical activity with sleep in under 5s: A systematic review and meta-analysis
Associations of screen time, sedentary time and physical activity with sleep in under 5s: A systematic review and meta-analysis Open
Sleep is crucial to children's health and development. Reduced physical activity and increased screen time adversely impact older children's sleep, but little is known about these associations in children under 5 y. This systematic review …
View article: Utilising active play in schools to improve physical activity and fundamental movement skills in Scottish children
Utilising active play in schools to improve physical activity and fundamental movement skills in Scottish children Open
It is widely accepted that children in Scotland, as in other high-income countries, are not engaging in sufficient moderate-to-vigorous intensity physical activity (MVPA), the consequences of which can be adverse for health and wellbeing. …
View article: Longitudinal changes in moderate‐to‐vigorous‐intensity physical activity in children and adolescents: A systematic review and meta‐analysis
Longitudinal changes in moderate‐to‐vigorous‐intensity physical activity in children and adolescents: A systematic review and meta‐analysis Open
Summary Moderate‐to‐vigorous‐intensity physical activity (MVPA) is important for childhood obesity prevention and treatment, yet declines with age. Timing and magnitude of the decline in MVPA in children and adolescents are unclear but imp…
View article: Physical activity interventions in early life aimed at reducing later risk of obesity and related non‐communicable diseases: A rapid review of systematic reviews
Physical activity interventions in early life aimed at reducing later risk of obesity and related non‐communicable diseases: A rapid review of systematic reviews Open
Summary To identify useful components of interventions aimed at prevention of childhood obesity and related non‐communicable diseases (NCDs), which included physical activity and which targeted any or all of four life‐course stages: peri‐c…
View article: Protocol for Healthy Habits Happy Homes (4H) Scotland: feasibility of a participatory approach to adaptation and implementation of a study aimed at early prevention of obesity
Protocol for Healthy Habits Happy Homes (4H) Scotland: feasibility of a participatory approach to adaptation and implementation of a study aimed at early prevention of obesity Open
Introduction Prevention of childhood obesity is an important public health objective. Promoting healthful energy balance related behaviours (EBRBs) in the early years should be a key focus. In Scotland, one in five children are overweight …
View article: An active play intervention to improve physical activity and fundamental movement skills in children of low socio-economic status: feasibility cluster randomised controlled trial
An active play intervention to improve physical activity and fundamental movement skills in children of low socio-economic status: feasibility cluster randomised controlled trial Open
View article: Feasibility of the ToyBox-Scotland obesity prevention intervention in preschools : results of a cluster randomised controlled trial
Feasibility of the ToyBox-Scotland obesity prevention intervention in preschools : results of a cluster randomised controlled trial Open
Introduction: The ToyBox-Scotland intervention is an 18-week practitioner-led programme that aims to increase physical activity, reduce sedentary behaviour, and promote healthy snacking and water consumption. We adapted the original Toybox…
View article: Adapting the ToyBox obesity prevention intervention for use in Scottish preschools: protocol for a feasibility cluster randomised controlled trial
Adapting the ToyBox obesity prevention intervention for use in Scottish preschools: protocol for a feasibility cluster randomised controlled trial Open
Introduction There is an increasing need for the adoption of effective preschool obesity prevention interventions to combat the high levels of early-childhood obesity in the UK. This study will examine the feasibility and acceptability of …
View article: Utilising active play interventions to promote physical activity and improve fundamental movement skills in children: a systematic review and meta-analysis
Utilising active play interventions to promote physical activity and improve fundamental movement skills in children: a systematic review and meta-analysis Open