Alex J. Barker
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View article: Third trimester fetal <scp>4D</scp> flow <scp>MRI</scp> with motion correction
Third trimester fetal <span>4D</span> flow <span>MRI</span> with motion correction Open
Purpose To correct maternal breathing and fetal bulk motion during fetal 4D flow MRI. Methods A Doppler‐ultrasound fetal cardiac‐gated free‐running 4D flow acquisition was corrected post hoc for maternal respiratory and fetal bulk motion i…
View article: Magnetic resonance quantification of regional blood flow and oxygen delivery to the brain, gut, kidneys, and lower extremities in adolescents with a Fontan circulation compared to biventricular controls
Magnetic resonance quantification of regional blood flow and oxygen delivery to the brain, gut, kidneys, and lower extremities in adolescents with a Fontan circulation compared to biventricular controls Open
Our results are consistent with a limited flow reserve in the Fontan circulation with sacrifice of iliac arterial flow as global systemic blood flow decreases. Importantly, these data were measured with subjects supine and at rest. Future …
View article: Assessment of diastolic function in overweight individuals with and without uncomplicated type 2 diabetes using comprehensive CMR and 4D flow MRI
Assessment of diastolic function in overweight individuals with and without uncomplicated type 2 diabetes using comprehensive CMR and 4D flow MRI Open
View article: Fetal cardiac MRI using doppler ultrasound for evaluation of thoracoomphalopagus conjoined twins
Fetal cardiac MRI using doppler ultrasound for evaluation of thoracoomphalopagus conjoined twins Open
View article: Left ventricular flow dynamics and energetics as hemodynamic markers for the assessment of myocardial response to bicuspid aortic stenosis
Left ventricular flow dynamics and energetics as hemodynamic markers for the assessment of myocardial response to bicuspid aortic stenosis Open
View article: Factors influencing image quality in fetal cardiovascular magnetic resonance cine imaging using Doppler ultrasound gating: A multicenter study
Factors influencing image quality in fetal cardiovascular magnetic resonance cine imaging using Doppler ultrasound gating: A multicenter study Open
Various factors (e.g. BMI) influence fetal cardiac cine MRI image quality. Understanding these factors may help achieving reliable examinations and better exploit the potential of fetal cardiac MRI in clinical routine.
View article: Reducing the sampling burden of Fourier sensing with a non-rectangular field-of-view
Reducing the sampling burden of Fourier sensing with a non-rectangular field-of-view Open
View article: Fetal CMR in restrictive atrial septum: Spicing up the nutmeg lung evaluation
Fetal CMR in restrictive atrial septum: Spicing up the nutmeg lung evaluation Open
View article: Pegloticase-Induced Rapid Uric Acid Lowering and Kidney and Cardiac Health Markers in Youth-Onset Type 2 Diabetes: A Pilot Clinical Trial
Pegloticase-Induced Rapid Uric Acid Lowering and Kidney and Cardiac Health Markers in Youth-Onset Type 2 Diabetes: A Pilot Clinical Trial Open
View article: Aortic shape with high-acute isthmic angle post frozen elephant trunk reconstruction is associated with worse postoperative outcomes: Multisite, principal component analysis, retrospective study
Aortic shape with high-acute isthmic angle post frozen elephant trunk reconstruction is associated with worse postoperative outcomes: Multisite, principal component analysis, retrospective study Open
Objective: Aortic shape and geometry after surgical reconstruction have been shown to be important determinants of flow hemodynamics, aortic remodeling, and clinical outcomes. In this study, we investigated aortic shapes post-frozen elepha…
View article: Summary: International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes
Summary: International consensus statement on nomenclature and classification of the congenital bicuspid aortic valve and its aortopathy, for clinical, surgical, interventional and research purposes Open
View article: Reducing the Sampling Burden of Fourier Sensing with a Non-rectangular Field-of-View
Reducing the Sampling Burden of Fourier Sensing with a Non-rectangular Field-of-View Open
With Fourier sensing, it is commonly the case that the field-of-view (FOV), the area of space to be imaged, is known prior to reconstruction. To date, reconstruction algorithms have focused on FOVs with simple geometries: a rectangle or a …
View article: Fetal Cardiac MRI Using Doppler US Gating: Emerging Technology and Clinical Implications
Fetal Cardiac MRI Using Doppler US Gating: Emerging Technology and Clinical Implications Open
Fetal cardiac MRI using Doppler US gating is an emerging technique to support prenatal diagnosis of congenital heart disease and other cardiovascular abnormalities. Analogous to postnatal electrocardiographically gated cardiac MRI, this te…
View article: Resumen: Consenso internacional para la nomenclatura y clasificación de la válvula aórtica bicúspide congénita y su aortopatía, con fines clínicos, quirúrgicos, intervencionistas y de investigación
Resumen: Consenso internacional para la nomenclatura y clasificación de la válvula aórtica bicúspide congénita y su aortopatía, con fines clínicos, quirúrgicos, intervencionistas y de investigación Open
This consensus of nomenclature and classification for congenital bicuspid aortic valve and its aortopathy is evidence-based and intended for universal use by physicians (both pediatricians and adults), echocardiographers, advanced cardiova…
View article: Assessment of abnormal transvalvular flow and wall shear stress direction for pediatric/young adults with bicuspid aortic valve: A cross-sectional four-dimensional flow study
Assessment of abnormal transvalvular flow and wall shear stress direction for pediatric/young adults with bicuspid aortic valve: A cross-sectional four-dimensional flow study Open
View article: Predictive Capability of Fetal 4D Flow and Black Blood Slice to Volume Reconstruction for Prenatal Diagnosis of Coarctation of the Aorta (CoA)
Predictive Capability of Fetal 4D Flow and Black Blood Slice to Volume Reconstruction for Prenatal Diagnosis of Coarctation of the Aorta (CoA) Open
View article: 3D Black Blood Images in the Assessment of Fetal Extracardiac Vasculature
3D Black Blood Images in the Assessment of Fetal Extracardiac Vasculature Open
View article: Fetal CMR Markers of Clinical Severity in Congenital Diaphragmatic Hernia (CDH)
Fetal CMR Markers of Clinical Severity in Congenital Diaphragmatic Hernia (CDH) Open
View article: Easing the strain of fetal cardiovascular magnetic resonance: Editorial for “Fetal cardiovascular magnetic resonance feature tracking myocardial strain analysis in congenital heart disease”
Easing the strain of fetal cardiovascular magnetic resonance: Editorial for “Fetal cardiovascular magnetic resonance feature tracking myocardial strain analysis in congenital heart disease” Open
View article: Assessment of Abnormal Transvalvular Flow and Wall Shear Stress for Pediatric/young Adults with Bicuspid Aortic Valve: A Cross-sectional 4D Flow Study
Assessment of Abnormal Transvalvular Flow and Wall Shear Stress for Pediatric/young Adults with Bicuspid Aortic Valve: A Cross-sectional 4D Flow Study Open
View article: Measurement of Time-resolved Septal Curvature to Assess Pediatric Pulmonary Hypertension
Measurement of Time-resolved Septal Curvature to Assess Pediatric Pulmonary Hypertension Open
View article: Biventricular Volumes and Strain in Fetuses with Suspected Coarctation of Aorta (CoA) Using Doppler Ultrasound Gated CMR
Biventricular Volumes and Strain in Fetuses with Suspected Coarctation of Aorta (CoA) Using Doppler Ultrasound Gated CMR Open
View article: Utilization of T2 Prep for MR Oximetery Combined with 4D Flow Phase Contrast Imaging for Evaluation of Extracardiac Organ Oxygen Metabolism in Fontan Patients
Utilization of T2 Prep for MR Oximetery Combined with 4D Flow Phase Contrast Imaging for Evaluation of Extracardiac Organ Oxygen Metabolism in Fontan Patients Open
View article: Valvular and ascending aortic hemodynamics of the On-X aortic valved conduit by same-day echocardiography and 4D flow MRI
Valvular and ascending aortic hemodynamics of the On-X aortic valved conduit by same-day echocardiography and 4D flow MRI Open
This study aims to assess whether the On-X aortic valved conduit better restores normal valvular and ascending aortic hemodynamics than other commonly used bileaflet mechanical valved conduit prostheses from St. Jude Medical and Carbomedic…
View article: 4D‐Flow MRI intracardiac flow analysis considering different subtypes of pulmonary hypertension
4D‐Flow MRI intracardiac flow analysis considering different subtypes of pulmonary hypertension Open
Intracardiac flow hemodynamic patterns have been considered to be an early sign of diastolic dysfunction. In this study we investigated right ventricular (RV) diastolic dysfunction between patients with pulmonary arterial hypertension (PAH…
View article: Obesity dominates early effects on cardiac structure and arterial stiffness in people with type 2 diabetes
Obesity dominates early effects on cardiac structure and arterial stiffness in people with type 2 diabetes Open
Objective: Type 2 diabetes (T2D) and obesity are global epidemics leading to excess cardiovascular disease (CVD). This study investigates standard and novel cardiac MRI parameters to detect subclinical cardiac and central vascular dysfunct…
View article: Myocardial strain-curve deformation patterns after Fontan operation
Myocardial strain-curve deformation patterns after Fontan operation Open
Myocardial deformation analysis by cardiac MRI (CMR) yielding global circumferential and longitudinal strain (GCS and GLS) is an increasingly utilized method to accurately quantify systolic function and predict clinical events in patients …
View article: The Inner Complexities of Multimodal Medical Data: Bitmap-Based 3D Printing for Surgical Planning Using Dynamic Physiology
The Inner Complexities of Multimodal Medical Data: Bitmap-Based 3D Printing for Surgical Planning Using Dynamic Physiology Open
Motivated by the need to develop more informative and data-rich patient-specific presurgical planning models, we present a high-resolution method that enables the tangible replication of multimodal medical data. By leveraging voxel-level c…
View article: A classification approach to improve out of sample predictability of structure‐based constitutive models for ascending thoracic aortic tissue
A classification approach to improve out of sample predictability of structure‐based constitutive models for ascending thoracic aortic tissue Open
In this research, a pipeline was developed to assess the out‐of‐sample predictive capability of structure‐based constitutive models of ascending aortic aneurysmal tissue. The hypothesis being tested is that a biomarker can help establish s…
View article: Aortic shape variation after frozen elephant trunk procedure predicts aortic events: Principal component analysis study
Aortic shape variation after frozen elephant trunk procedure predicts aortic events: Principal component analysis study Open
The second principal component, describing angulation at the region of the aortic isthmus, was associated with adverse aortic events. Observed shape variation should be evaluated in the context of aortic biomechanical properties and flow h…