Alex J. Warr
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View article: P-1863. Maternal Mycobacterial-Specific T-cell Signatures and Infant Risk of <i>Mycobacterium tuberculosis</i> Infection
P-1863. Maternal Mycobacterial-Specific T-cell Signatures and Infant Risk of <i>Mycobacterium tuberculosis</i> Infection Open
Background Tuberculosis disease (TB) caused 214,000 pediatric deaths in 2022. A growing body of evidence suggests that HIV exposed uninfected infants (iHEU) are at increased risk for Mycobacterium tuberculosis (Mtb) infection. Harnessing t…
View article: A CD4+ TNF+ monofunctional memory T-cell response to BCG vaccination is associated with Mycobacterium tuberculosis infection in infants exposed to HIV
A CD4+ TNF+ monofunctional memory T-cell response to BCG vaccination is associated with Mycobacterium tuberculosis infection in infants exposed to HIV Open
Thrasher Research Fund.
View article: Non-IFNγ Whole Blood Cytokine Responses to Mycobacterium tuberculosis Antigens in HIV-exposed Infants
Non-IFNγ Whole Blood Cytokine Responses to Mycobacterium tuberculosis Antigens in HIV-exposed Infants Open
Background: HIV-exposed uninfected (HEU) infants have increased risk of tuberculosis (TB). Testing for Mycobacterium tuberculosis (Mtb) infection is limited by reduced Quantiferon (QFT) sensitivity in infants and tuberculin skin test (TST)…
View article: CNBP, REL, and BHLHE40 variants are associated with IL-12 and IL-10 responses and tuberculosis risk
CNBP, REL, and BHLHE40 variants are associated with IL-12 and IL-10 responses and tuberculosis risk Open
Rationale The major human genes regulating M. tuberculosis (Mtb)-induced immune responses and tuberculosis (TB) susceptibility are poorly understood. Although IL-12 and IL-10 are critical for TB pathogenesis, the genetic factors that regul…
View article: Pulmonary tuberculosis screening in anti-retroviral treated adults living with HIV in Kenya
Pulmonary tuberculosis screening in anti-retroviral treated adults living with HIV in Kenya Open
View article: Maternal chlamydia infection, preterm birth, and travel time to clinic associated with increased infant mortality: a nested case-control study in Kenya
Maternal chlamydia infection, preterm birth, and travel time to clinic associated with increased infant mortality: a nested case-control study in Kenya Open
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