Alex Kan
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View article: Correlation Between Cryptococcus Infection and the Nasal Mycobiota in a Population of Free-Ranging Koalas (Phascolarctos cinereus) in New South Wales, Australia
Correlation Between Cryptococcus Infection and the Nasal Mycobiota in a Population of Free-Ranging Koalas (Phascolarctos cinereus) in New South Wales, Australia Open
Cryptococcosis is a fungal disease in humans and animals, caused by the Cryptococcus neoformans and Cryptococcus gattii species complexes. Clinical cryptococcosis primarily manifests as upper respiratory tract disease; however, disseminati…
View article: Long‐term renal outcomes of children with cancers treated with platinum‐based chemotherapy: A retrospective chart analysis
Long‐term renal outcomes of children with cancers treated with platinum‐based chemotherapy: A retrospective chart analysis Open
Purpose Platinum‐based chemotherapy is a mainstay of treatment for many childhood cancers but is associated with acute nephrotoxicity and long‐term ototoxicity. There is emerging evidence of long‐term renal complications. This study aimed …
View article: Metal Complexes as Antifungals? From a Crowd-Sourced Compound Library to the First <i>In Vivo</i> Experiments
Metal Complexes as Antifungals? From a Crowd-Sourced Compound Library to the First <i>In Vivo</i> Experiments Open
There are currently fewer than 10 antifungal drugs in clinical development, but new fungal strains that are resistant to most current antifungals are spreading rapidly across the world. To prevent a second resistance crisis, new classes of…
View article: Metal Complexes as Antifungals? – From a Crowd-Sourced Compound Library to First In Vivo Experiments
Metal Complexes as Antifungals? – From a Crowd-Sourced Compound Library to First In Vivo Experiments Open
There are currently fewer than ten antifungal drugs in clinical development, but new fungal strains, which are resistant to most current antifungals are spreading rapidly across the world. To prevent a second resistance crisis, new classes…
View article: A Possible Link between the Environment and Cryptococcus gattii Nasal Colonisation in Koalas (Phascolarctos cinereus) in the Liverpool Plains, New South Wales
A Possible Link between the Environment and Cryptococcus gattii Nasal Colonisation in Koalas (Phascolarctos cinereus) in the Liverpool Plains, New South Wales Open
Cryptococcosis caused by yeasts of the Cryptococcus gattii species complex is an increasingly important mycological disease in humans and other mammals. In Australia, cases of C. gattii-related cryptococcosis are more prevalent in the koal…
View article: Multilocus Sequence Typing Reveals Extensive Genetic Diversity of the Emerging Fungal Pathogen Scedosporium aurantiacum
Multilocus Sequence Typing Reveals Extensive Genetic Diversity of the Emerging Fungal Pathogen Scedosporium aurantiacum Open
Scedosporium spp. are the second most prevalent filamentous fungi after Aspergillus spp. recovered from cystic fibrosis (CF) patients in various regions of the world. Although invasive infection is uncommon prior to lung transplantation, f…
View article: Cryptococcus gattii Species Complex as an Opportunistic Pathogen: Underlying Medical Conditions Associated with the Infection
Cryptococcus gattii Species Complex as an Opportunistic Pathogen: Underlying Medical Conditions Associated with the Infection Open
The C. neoformans and C. gattii species complex causes cryptococcosis. The C. neoformans species complex is known as an opportunistic pathogen since it primarily infects immunocompromised patients. C. gattii species complex has been referr…
View article: Consensus Multilocus Sequence Typing Scheme for Pneumocystis jirovecii
Consensus Multilocus Sequence Typing Scheme for Pneumocystis jirovecii Open
Pneumocystis jirovecii is an opportunistic human pathogenic fungus causing severe pneumonia mainly in immunocompromised hosts. Multilocus sequence typing (MLST) remains the gold standard for genotyping of this unculturable fungus. However,…
View article: Identification of the environmental source of infection for a domestic ferret with cryptococcosis
Identification of the environmental source of infection for a domestic ferret with cryptococcosis Open
Cryptococcosis, caused by the Cryptococcus gattii and C. neoformans species complexes, is an environmentally acquired mycosis affecting a broad range of host species. Among 9 communally housed ferrets, a 5-y-old castrated male ferret domic…
View article: Australian medical mycology culture collections: fundamental resources for mycological diagnosis and research
Australian medical mycology culture collections: fundamental resources for mycological diagnosis and research Open
Currently in Australia, there are four major medical mycology culture collections that form a close collaborative network. They provide fundamental resources for diagnosis and research and are part of the World Federation of Culture Collec…