Andrea Low
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View article: A Systematic Review and Meta‐Analysis of the Birth Prevalence of Turner Syndrome
A Systematic Review and Meta‐Analysis of the Birth Prevalence of Turner Syndrome Open
Turner syndrome, a chromosomal disorder, causes short stature, pubertal arrest, amenorrhea, and infertility in females. Prevalence estimates vary widely; however, reliable estimates are important for public health initiatives. Therefore, a…
View article: Comparative analysis of asbestos body and fiber content in formalin-fixed vs. paraffin-embedded lung tissue
Comparative analysis of asbestos body and fiber content in formalin-fixed vs. paraffin-embedded lung tissue Open
Introduction Asbestos body and fiber burdens may be determined using different preparations of lung tissue. Paraffin-embedded tissue requires more complex steps than formalin-fixed tissue. A prior study highlighted potential variations in …
View article: Extreme geographic misalignment of healthcare resources and HIV treatment deserts in Malawi
Extreme geographic misalignment of healthcare resources and HIV treatment deserts in Malawi Open
The Joint United Nations Programme on HIV and AIDS has proposed that human rights should be at the center of efforts to end the HIV pandemic and achieving equity in access to antiretroviral therapy (ART) and HIV healthcare is essential. He…
View article: Performance of Risk‐Stratification Scores for Patients With Pulmonary Arterial Hypertension in a Multi‐Ethnic Asian Population
Performance of Risk‐Stratification Scores for Patients With Pulmonary Arterial Hypertension in a Multi‐Ethnic Asian Population Open
Guidelines recommend risk stratification of pulmonary arterial hypertension (PAH) patients to guide management. There are currently several risk stratification scores available, which have largely been validated in various pulmonary hypert…
View article: Persistent growth-promoting effects of vosoritide in children with achondroplasia are accompanied by improvements in physical and social aspects of health-related quality of life
Persistent growth-promoting effects of vosoritide in children with achondroplasia are accompanied by improvements in physical and social aspects of health-related quality of life Open
These data suggest that after 3 years of treatment, vosoritide demonstrates a positive effect on physical and social functioning among children with achondroplasia, particularly in children with a more pronounced change in height z-score.
View article: Prevalence of monoclonal gammopathy of undetermined significance in Eswatini: a population-based study in Africa
Prevalence of monoclonal gammopathy of undetermined significance in Eswatini: a population-based study in Africa Open
Background Although monoclonal gammopathy of undetermined significance (MGUS) and multiple myeloma disproportionately affect Black individuals, few epidemiological studies have been conducted on these plasma cell disorders in Africa. Here …
View article: Investigating the Associations between Drought, Poverty, High-Risk Sexual Behaviours, and HIV Incidence in Sub-Saharan Africa: A Cross-Sectional Study
Investigating the Associations between Drought, Poverty, High-Risk Sexual Behaviours, and HIV Incidence in Sub-Saharan Africa: A Cross-Sectional Study Open
Climate change is increasing the likelihood of drought in sub-Saharan Africa, where HIV prevalence is high. Drought could increase HIV transmission through various mediating mechanisms; we investigated these associations. We used data on p…
View article: P139: Persistent growth-promoting effects of vosoritide in children with achondroplasia for up to 4 years: Update from phase 3 extension study*
P139: Persistent growth-promoting effects of vosoritide in children with achondroplasia for up to 4 years: Update from phase 3 extension study* Open
Vosoritide, a potent stimulator of endochondral bone growth, is approved for use in children with achondroplasia (ACH) until closure of epiphyses. A 52-week, phase 3, pivotal trial demonstrated a significant improvement in annualized growt…
View article: Psoriatic arthritis: the role of self-reported non-adherence, non-trough drug levels, immunogenicity and conventional synthetic DMARD co-therapy in adalimumab and etanercept response
Psoriatic arthritis: the role of self-reported non-adherence, non-trough drug levels, immunogenicity and conventional synthetic DMARD co-therapy in adalimumab and etanercept response Open
Objective The aim of this study was to assess the relationship between self-reported non-adherence, non-trough drug levels, immunogenicity and conventional synthetic DMARD (csDMARD) co-therapy in TNF inhibitor (TNF-i) drug response in PsA.…
View article: Non-trough serum drug levels of adalimumab and etanercept are associated with response in patients with psoriatic arthritis
Non-trough serum drug levels of adalimumab and etanercept are associated with response in patients with psoriatic arthritis Open
Objectives Up to 40% of PsA patients experience first-line tumour necrosis factor inhibitors (TNF-i) failure. Lower serum drug levels (SDL) have been associated with lower response in autoimmune conditions. This study aimed to: (i) establi…
View article: Prevalence and factors associated with flares following COVID-19 mRNA vaccination in patients with rheumatoid arthritis, psoriatic arthritis and spondyloarthritis: a national cohort study
Prevalence and factors associated with flares following COVID-19 mRNA vaccination in patients with rheumatoid arthritis, psoriatic arthritis and spondyloarthritis: a national cohort study Open
Objective To determine prevalence and factors associated with flares post Coronavirus disease 2019 (COVID-19) mRNA vaccination in patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA) and spondyloarthritis (SpA). Methods A ret…
View article: How does HIV-related stigma correlate with HIV prevalence in African countries? Distinct perspectives from individuals living with and living without HIV
How does HIV-related stigma correlate with HIV prevalence in African countries? Distinct perspectives from individuals living with and living without HIV Open
Background: Population-level research evaluating HIV-related stigma among countries with varied national HIV prevalence is scarce. To better understand HIV-related stigma and mitigate its potential negative effects, it is necessary to eval…
View article: Contraception and intersection with <scp>HIV</scp> services in 11 high <scp>HIV</scp> burden <scp>sub‐Saharan</scp> African countries: Results from the population‐based <scp>HIV</scp> Impact Assessment cross‐sectional studies conducted from 2015 to 2018
Contraception and intersection with <span>HIV</span> services in 11 high <span>HIV</span> burden <span>sub‐Saharan</span> African countries: Results from the population‐based <span>HIV</span> Impact Assessment cross‐sectional studies conducted from 2015 to 2018 Open
Objective The United Nations' Sustainable Development Goal 3.7.1 addresses the importance of family planning. The objective of this paper is to provide information on family planning to policymakers to help increase access to contraceptive…
View article: Prevalence and factors associated with flares following COVID-19 mRNA vaccination in patients with rheumatoid arthritis, psoriatic arthritis and spondyloarthritis: a national cohort study
Prevalence and factors associated with flares following COVID-19 mRNA vaccination in patients with rheumatoid arthritis, psoriatic arthritis and spondyloarthritis: a national cohort study Open
Objective To determine prevalence and factors associated with flares post Coronavirus disease 2019 (COVID-19) mRNA vaccination in patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA) and spondyloarthritis (SpA). Methods A ret…
View article: Real-world outcomes of Selexipag for treatment of pulmonary hypertension in an Asian population
Real-world outcomes of Selexipag for treatment of pulmonary hypertension in an Asian population Open
Funding Acknowledgements Type of funding sources: None. Introduction Selexipag is an oral selective prostacyclin IP receptor agonist indicated for treatment of pulmonary arterial hypertension (PAH). Data on its real-world safety and effica…
View article: Hazardous alcohol use and HIV indicators in six African countries: results from the Population‐based HIV Impact Assessments, 2015–2017
Hazardous alcohol use and HIV indicators in six African countries: results from the Population‐based HIV Impact Assessments, 2015–2017 Open
Introduction Hazardous alcohol use (HAU), defined as a pattern of alcohol consumption that increases the risk of harmful consequences for the user or others, is associated with an elevated risk of human immunodeficiency virus (HIV) infecti…