Alex Symonds
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View article: Axonal response of mitochondria to demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis
Axonal response of mitochondria to demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis Open
Aims Axonal injury in multiple sclerosis (MS) and experimental models is most frequently detected in acutely demyelinating lesions. We recently reported a compensatory neuronal response, where mitochondria move to the acutely demyelinated …
View article: The role of complex IV activity in the axonal response of mitochondria to demyelination in experimental disease models of multiple sclerosis
The role of complex IV activity in the axonal response of mitochondria to demyelination in experimental disease models of multiple sclerosis Open
Axon loss is a cardinal neuropathological feature of multiple sclerosis (MS). Axonal injury in MS and experimental disease models is most frequently detected in acutely demyelinating regions. Furthermore, acute axonal injury consistently c…