Alex Tagawa
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View article: The state of the art exercise recommendations for older adults with cognitive impairments: A meta‐analysis of the meta‐analysis
The state of the art exercise recommendations for older adults with cognitive impairments: A meta‐analysis of the meta‐analysis Open
Background There is accumulative evidence supporting the benefits of regular physical activity in improving cognition in older adults with cognitive impairments (OAwCIs). In the past decades, multiple meta‐analyses (MA) have been published…
View article: The association between isometric strength and cognitive function in adults with cerebral palsy
The association between isometric strength and cognitive function in adults with cerebral palsy Open
Background The literature supports quantifying the maximum force/tension generated by one’s forearm muscles such as the hand grip strength (HGS) to screen for physical and cognitive frailty in older adults. Thus, we postulate that individu…
View article: Previous corticosteroid exposure associates with an increased <i>Pneumocystis jirovecii</i> pneumonia mortality among HIV-negative patients: a global research network with a follow-up multicenter case-control study
Previous corticosteroid exposure associates with an increased <i>Pneumocystis jirovecii</i> pneumonia mortality among HIV-negative patients: a global research network with a follow-up multicenter case-control study Open
Background: HIV-negative patients have substantial mortality from Pneumocystis jirovecii pneumonia (PJP). We lack predictors of HIV-negative PJP-associated mortality. Objective: We aim to characterize the role of prior corticosteroid expos…
View article: 472. Corticosteroid Exposure as a Risk Factor for <i>Pneumocystis jirovecii</i> Pneumonia Mortality in HIV-Negative Patients: A Multicenter Retrospective Case-Control Study with a Global Research Network Validation
472. Corticosteroid Exposure as a Risk Factor for <i>Pneumocystis jirovecii</i> Pneumonia Mortality in HIV-Negative Patients: A Multicenter Retrospective Case-Control Study with a Global Research Network Validation Open
Background HIV-negative patients have higher mortality from PJP compared to patients with HIV, however, we lack data on predictors of PJP-associated mortality in HIV-negative patients. We aim to characterize the role of previous corticoste…
View article: 473. Diabetes Mellitus as a Risk Factor for Cryptococcosis — a Multicenter Research Network Study
473. Diabetes Mellitus as a Risk Factor for Cryptococcosis — a Multicenter Research Network Study Open
Background Diabetes mellitus type 2 (DM2) is a common medical condition that increases the risk of bacterial infections, and is often present in patients with cryptococcosis. The role of DM2 as an independent risk factor for cryptococcosis…
View article: 1383. Necrotizing Fasciitis and <i>Streptococcus pyogenes</i> (GAS) Infection Seasonality and Risk Factors for Infection— a Multicenter Research Network Study
1383. Necrotizing Fasciitis and <i>Streptococcus pyogenes</i> (GAS) Infection Seasonality and Risk Factors for Infection— a Multicenter Research Network Study Open
Background Streptococcus pyogenes causes acute pharyngitis and type II necrotizing fasciitis. Seasonal variations in the incidence of S. pyogenes infections are not robustly characterized. We aim to identify seasonal variations and risk fa…
View article: Associations of Circulating Insulin-Growth Factor-1 With Cognitive Functions and Quality of Life Domains in Ambulatory Young Adults With Cerebral Palsy: A Pilot Study
Associations of Circulating Insulin-Growth Factor-1 With Cognitive Functions and Quality of Life Domains in Ambulatory Young Adults With Cerebral Palsy: A Pilot Study Open
Objective Adults with cerebral palsy (CP) often have impaired cognitive functions. CP also has deteriorations in multiple quality-of-life (QoL) domains. The bio-psycho-social health psychology model posits that biological factor interacts …
View article: Seasonal variations and risk factors of <i>Streptococcus pyogenes</i> infection: a multicenter research network study
Seasonal variations and risk factors of <i>Streptococcus pyogenes</i> infection: a multicenter research network study Open
Background: Streptococcus pyogenes, or Group A Streptococcus (GAS), causes acute pharyngitis and necrotizing fasciitis. Seasonal variations in GAS infections are not robustly characterized. We assessed seasonal variations and risk factors …
View article: Sex Differences in Cardiovascular Markers and BDNF between Cerebral Palsy and Mild Cognitive Impairment
Sex Differences in Cardiovascular Markers and BDNF between Cerebral Palsy and Mild Cognitive Impairment Open
Adults with cerebral palsy (CP) have higher risk of developing geriatric syndromes. Mild cognitive impairment (MCI) is an intermediate stage between healthy aging and dementia, often co-morbid with cardiovascular disease (CVD). We recently…
View article: Increased plasma brain-derived neurotrophic factor (BDNF) as a potential biomarker for and compensatory mechanism in mild cognitive impairment: a case-control study
Increased plasma brain-derived neurotrophic factor (BDNF) as a potential biomarker for and compensatory mechanism in mild cognitive impairment: a case-control study Open
These findings suggest BDNF is increased as a compensatory mechanism in preclinical dementia, supporting the neurotrophic and partially the inflammatory hypotheses of cognitive impairment.
View article: Commonalities in biomarkers and phenotypes between mild cognitive impairment and cerebral palsy: a pilot exploratory study
Commonalities in biomarkers and phenotypes between mild cognitive impairment and cerebral palsy: a pilot exploratory study Open
Clinically, individuals with cerebral palsy (CP) experience symptoms of accelerated biological aging. Accumulative deficits in both molecular underpinnings and functions in young adults with CP can lead to premature aging, such as heart di…
View article: Insulin‐like growth factor‐1 (IGF‐1) is a biomarker of objective cognitive impairment but not subjective cognitive complaint in cerebral palsy
Insulin‐like growth factor‐1 (IGF‐1) is a biomarker of objective cognitive impairment but not subjective cognitive complaint in cerebral palsy Open
Background Cognitive impairments are common in cerebral palsy (CP), however the evidence on the biological underpinnings of these impairments in CP has been scarce. Although insulin‐like growth factor‐1 (IGF‐1) is involved in cognitive def…
View article: Evidence-Based Exercise Recommendations for Older Adults With Cognitive Impairments
Evidence-Based Exercise Recommendations for Older Adults With Cognitive Impairments Open
Since the publishing of our meta-analysis evaluating the effects of randomized exercise trials on cognitive function of Older Adults with Cognitive Impairments (OAwCIs) (Heyn et al 2004), several meta-analysis reviews were published addres…
View article: Distinct and common biomarkers and phenotypes in cerebral palsy and mild cognitive impairment: An exploratory study
Distinct and common biomarkers and phenotypes in cerebral palsy and mild cognitive impairment: An exploratory study Open
Background Cerebral palsy (CP) patients have accelerated aging, impairments in various pathology and anthropometry, and may develop geriatric syndromes, particularly cognitive impairment. Mild cognitive impairment (MCI) is an intermediate …
View article: ISOKINETIC PERFORMANCE AND LIMB ASYMMETRY DIFFERENCES BETWEEN ADOLESCENT MALES AND FEMALES FOLLOWING QUADRICEPS TENDON – PATELLAR BONE AUTOGRAFT ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION
ISOKINETIC PERFORMANCE AND LIMB ASYMMETRY DIFFERENCES BETWEEN ADOLESCENT MALES AND FEMALES FOLLOWING QUADRICEPS TENDON – PATELLAR BONE AUTOGRAFT ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION Open
Background: Accurate measurement of limb strength asymmetry differences between sexes may be important to consider when determining readiness to return to sport among adolescents following ACL reconstruction. Hypothesis/Purpose: The purpos…
View article: Prevalence of metabolic syndrome and cardiovascular disease risk factors in adults with cerebral palsy
Prevalence of metabolic syndrome and cardiovascular disease risk factors in adults with cerebral palsy Open
Aim To investigate the prevalence of metabolic syndrome and cardiovascular disease ( CVD ) risk factors and the association between common metabolic markers and Gross Motor Function Classification System ( GMFCS ) levels in ambulatory adul…
View article: A SELF-HEALTH EMPOWERMENT AND WELLNESS MANAGEMENT APPROACH FOR INDIVIDUALS AGING WITH COMPLEX HEALTH CONDITIONS
A SELF-HEALTH EMPOWERMENT AND WELLNESS MANAGEMENT APPROACH FOR INDIVIDUALS AGING WITH COMPLEX HEALTH CONDITIONS Open
FiEffective approaches to promote self-health and wellness empowerment for individuals with complex health conditions must be person-focused and multi-disciplinary to be successful. The goal of such program is to support patients and careg…
View article: AGING WITH A PHYSICAL DISABILITY: FINDINGS AND IMPLICATIONS FROM THE CEREBRAL PALSY ADULT TRANSITION STUDY (CPAT)
AGING WITH A PHYSICAL DISABILITY: FINDINGS AND IMPLICATIONS FROM THE CEREBRAL PALSY ADULT TRANSITION STUDY (CPAT) Open
We investigated cardiovascular disease risk factors (CVDRFs) and the association between CVDRFs and gross motor function with the Gross Motor Function Classification System (GMFCS) in 70 adults with cerebral palsy (CP) who were ambulatory.…
View article: EFFECTS OF RANDOMIZED EXERCISE TRAINING ON COGNITION OF OLDER ADULTS WITH COGNITIVE IMPAIRMENTS: AN UMBRELLA REVIEW
EFFECTS OF RANDOMIZED EXERCISE TRAINING ON COGNITION OF OLDER ADULTS WITH COGNITIVE IMPAIRMENTS: AN UMBRELLA REVIEW Open
There is accumulative evidence supporting the benefits of regular physical activity along the cognitive role of older adults with cognitive impairments (OAwCIs). Since the publishing of our meta-analytic review evaluating the effects of ra…
View article: A PERSON-FOCUSED HEALTH PROMOTION AND WELLNESS APPROACH TO EXTEND HEALTHSPAN IN ADULTS WITH DISABILITIES: THE CHAMP - D
A PERSON-FOCUSED HEALTH PROMOTION AND WELLNESS APPROACH TO EXTEND HEALTHSPAN IN ADULTS WITH DISABILITIES: THE CHAMP - D Open
This presentation will discuss the findings from a person-focused health and wellness approach to healthspan called Comprehensive Health Assessment and Motivation Program for Individuals with Disabilities (CHAMP-D). The CHAMP-D is a health…
View article: Combined transcranial direct current stimulation and robotic upper limb therapy improves upper limb function in adults with cerebral palsy
Combined transcranial direct current stimulation and robotic upper limb therapy improves upper limb function in adults with cerebral palsy Open
View article: Search strategy for: The effects of exercise training on elderly persons with cognitive impairments and dementia: an umbrella review synthesis of the randomized controlled meta-analysis
Search strategy for: The effects of exercise training on elderly persons with cognitive impairments and dementia: an umbrella review synthesis of the randomized controlled meta-analysis Open
This document shows the Ovid Medline search strategy for the review entitled, “The Effects of Exercise Training on Elderly Persons with Cognitive Impairments and Dementia: An Umbrella Review Synthesis of the Randomized Controlled Meta-Anal…
View article: DIAGNOSING METABOLIC SYNDROME IN INDIVIDUALS WITH MOTOR DISABILITIES
DIAGNOSING METABOLIC SYNDROME IN INDIVIDUALS WITH MOTOR DISABILITIES Open
People with disability are subject to increased Metabolic Syndrome (MetSyn). There is strong evidence supporting the adoption of the MetSyn criteria to capture cardiovascular disease (CVD) risk factors in the general population. However, t…