Alexander G. Dimitrov
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View article: Sleep and diurnal alternative polyadenylation sites associated with human APA-linked brain disorders
Sleep and diurnal alternative polyadenylation sites associated with human APA-linked brain disorders Open
Disruption of sleep and circadian rhythms are a comorbid feature of many pathologies, and can negatively influence many health conditions, including neurodegenerative disease, metabolic illness, cancer, and various neurological disorders. …
View article: Sleep and diurnal alternative polyadenylation sites associated with human APA-linked brain disorders
Sleep and diurnal alternative polyadenylation sites associated with human APA-linked brain disorders Open
Disruption of sleep and circadian rhythms are a comorbid feature of many pathologies, and can negatively influence many health conditions, including neurodegenerative disease, metabolic illness, cancer, and various neurological disorders. …
View article: Identification of sleep and circadian alternative polyadenylation sites associated with APA-linked human brain disorders
Identification of sleep and circadian alternative polyadenylation sites associated with APA-linked human brain disorders Open
Sleep and circadian rhythm disruptions are comorbid features of many pathologies and can negatively influence numerous health conditions, including degenerative diseases, metabolic illnesses, cancer, and various neurological disorders. Gen…
View article: Sensitivity analysis of point neuron model simulations implemented on neuromorphic hardware
Sensitivity analysis of point neuron model simulations implemented on neuromorphic hardware Open
With the ongoing growth in the field of neuro-inspired computing, newly arriving computational architectures demand extensive validation and testing against existing benchmarks to establish their competence and value. In our work, we break…
View article: Corrigendum: Mapping and validating a point neuron model on intel's neuromorphic hardware Loihi
Corrigendum: Mapping and validating a point neuron model on intel's neuromorphic hardware Loihi Open
[This corrects the article DOI: 10.3389/fnins.2022.883360.].
View article: Symmetry-Breaking Bifurcations of the Information Bottleneck and Related Problems
Symmetry-Breaking Bifurcations of the Information Bottleneck and Related Problems Open
In this paper, we investigate the bifurcations of solutions to a class of degenerate constrained optimization problems. This study was motivated by the Information Bottleneck and Information Distortion problems, which have been used to suc…
View article: Mapping and Validating a Point Neuron Model on Intel's Neuromorphic Hardware Loihi
Mapping and Validating a Point Neuron Model on Intel's Neuromorphic Hardware Loihi Open
Neuromorphic hardware is based on emulating the natural biological structure of the brain. Since its computational model is similar to standard neural models, it could serve as a computational accelerator for research projects in the field…
View article: Mapping and Validating a Point Neuron Model on Intel's Neuromorphic Hardware Loihi
Mapping and Validating a Point Neuron Model on Intel's Neuromorphic Hardware Loihi Open
Neuromorphic hardware is based on emulating the natural biological structure of the brain. Since its computational model is similar to standard neural models, it could serve as a computational accelerator for research projects in the field…
View article: Generation of FHIR-Based International Patient Summaries from ELGA Data
Generation of FHIR-Based International Patient Summaries from ELGA Data Open
Patient summaries grant healthcare providers a concise overview of a patient’s status. This paper showcases to which degree International Patient Summaries (IPS) represented in HL7 FHIR format can be generated using data from the nationwid…
View article: The Lack of Convexity of the Relevance-Compression Function
The Lack of Convexity of the Relevance-Compression Function Open
In this paper we investigate the convexity of the relevance-compression function for the Information Bottleneck and the Information Distortion problems. This curve is an analog of the rate-distortion curve, which is convex. In the problems…
View article: Selectively caring for the most severe COVID-19 patients delays ICU bed shortages more than increasing hospital capacity
Selectively caring for the most severe COVID-19 patients delays ICU bed shortages more than increasing hospital capacity Open
1 Abstract SARS-CoV-2, the virus responsible for COVID-19, has killed hundreds of thousands of Americans. Although physical distancing measures played a key role in slowing COVID-19 spread in early 2020, infection rates are now peaking at …
View article: Invariance to frequency and time dilation along the ascending ferret auditory system
Invariance to frequency and time dilation along the ascending ferret auditory system Open
View article: Towards a Dynamic Clamp for Neurochemical Modalities
Towards a Dynamic Clamp for Neurochemical Modalities Open
The classic dynamic clamp technique uses a real-time electrical interface between living cells and neural simulations in order to investigate hypotheses about neural function and structure. One of the acknowledged drawbacks of that techniq…
View article: Emergence of perceptual invariances in auditory processes
Emergence of perceptual invariances in auditory processes Open