Alexander I. Murphy
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View article: Germline-targeting chimpanzee SIV Envelopes induce V2-apex broadly neutralizing-like B cell precursors in a rhesus macaque infection model
Germline-targeting chimpanzee SIV Envelopes induce V2-apex broadly neutralizing-like B cell precursors in a rhesus macaque infection model Open
SUMMARY Eliciting broadly neutralizing antibodies-(bnAbs) remains a major goal of HIV-1 vaccine research. Previously, we showed that a soluble chimpanzee SIV Envelope-(Env) trimer, MT145K, bound several human V2-apex bnAb-precursors and st…
View article: Industry Payments and Academic Influence in Reconstructive Microsurgery
Industry Payments and Academic Influence in Reconstructive Microsurgery Open
Background Financial relationships between industry and microsurgeons help facilitate innovation but have the potential to bias a surgeon's academic work. To better understand industry–academic relationships, this study investigated the as…
View article: Disparities in Research during Plastic Surgery Training: How Can We Level the Playing Field?
Disparities in Research during Plastic Surgery Training: How Can We Level the Playing Field? Open
Background: Lack of female and ethnically underrepresented in medicine (UIM) surgeons remains concerning in academic plastic surgery. One barrier to inclusion may be unequal opportunity to publish research. This study evaluates the extent …
View article: Identifying US Plastic Surgery Training Programs that Effectively Establish Gender and Ethnically Diverse Faculty
Identifying US Plastic Surgery Training Programs that Effectively Establish Gender and Ethnically Diverse Faculty Open
Background: Successful strategies to improve the representation of female and ethnically underrepresented in medicine (UIM) physicians among US plastic and reconstructive surgery (PRS) faculty have not been adequately explored. Accordingly…
View article: Closing the Gap: Training Experiences and Career Outcomes for Underrepresented Minorities in Plastic Surgery
Closing the Gap: Training Experiences and Career Outcomes for Underrepresented Minorities in Plastic Surgery Open
Background: The present study assesses training characteristics, scholastic achievements, and traditional career accomplishments of ethnically underrepresented in medicine (UIM) plastic and reconstructive surgery (PRS) faculty relative to …
View article: Leadership Roles, Academic Appointments, and Scholarly Activity—Does a Fellowship after Plastic Surgery Training Make a Difference?
Leadership Roles, Academic Appointments, and Scholarly Activity—Does a Fellowship after Plastic Surgery Training Make a Difference? Open
Background Fellowship training is becoming more popular in plastic surgery, with over half of residents pursuing advanced training. Here, we investigate how clinical and research fellowship training impacts career trajectory and scholastic…
View article: Identifying US Plastic Surgery Training Programs that Effectively Establish Gender and Ethnically Diverse Faculty
Identifying US Plastic Surgery Training Programs that Effectively Establish Gender and Ethnically Diverse Faculty Open
OBJECTIVE: The lack of female and ethnically underrepresented in medicine (UIM) physicians in plastic and reconstructive surgery (PRS) faculty has been well described in the literature. What remains unknown is how the field can effectively…
View article: Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth
Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth Open
Convergent HIV evolution across species Human immunodeficiency virus (HIV) has a highly diverse envelope protein that it uses to target human cells, and the complexity of the viral envelope has stymied vaccine development. Roark et al. rep…
View article: Recapitulation of HIV-1 Env-Antibody Coevolution in Macaques Leading to Neutralization Breadth
Recapitulation of HIV-1 Env-Antibody Coevolution in Macaques Leading to Neutralization Breadth Open
Neutralizing antibodies elicited by HIV-1 coevolve with viral Envs in distinctive patterns, in some cases acquiring substantial breadth. Here we show that primary HIV-1 Envs, when expressed by simian-human immunodeficiency viruses in rhesu…