Alexander L. Matveyev
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View article: Optical Coherence Elastography—A Novel Non-Invasive Optical Method for Real-Time Determination of Substances Penetration and Associated Skin Dehydration
Optical Coherence Elastography—A Novel Non-Invasive Optical Method for Real-Time Determination of Substances Penetration and Associated Skin Dehydration Open
Non-invasive, in vivo assessment of target substances penetration into the skin remains a significant challenge in dermatology and cosmetology. While various optical methods have been employed for this purpose, each has inherent limitation…
View article: Geophysics-Inspired Nonlinear Stress–Strain Law for Biological Tissues and Its Applications in Compression Optical Coherence Elastography
Geophysics-Inspired Nonlinear Stress–Strain Law for Biological Tissues and Its Applications in Compression Optical Coherence Elastography Open
We propose a nonlinear stress–strain law to describe nonlinear elastic properties of biological tissues using an analogy with the derivation of nonlinear constitutive laws for cracked rocks. The derivation of such a constitutive equation h…
View article: Computationally efficient adaptive optimization of vector-method parameters for phase-sensitive strain estimation in optical coherence elastography
Computationally efficient adaptive optimization of vector-method parameters for phase-sensitive strain estimation in optical coherence elastography Open
A new method for automatic adaptive optimization of strain estimation in phase-sensitive optical coherence tomography (OCT) is introduced. More specifically, this paper focuses on optimizing the estimation of strain using the vector method…
View article: K-Space Approach in Optical Coherence Tomography: Rigorous Digital Transformation of Arbitrary-Shape Beams, Aberration Elimination and Super-Refocusing beyond Conventional Phase Correction Procedures
K-Space Approach in Optical Coherence Tomography: Rigorous Digital Transformation of Arbitrary-Shape Beams, Aberration Elimination and Super-Refocusing beyond Conventional Phase Correction Procedures Open
For the most popular method of scan formation in Optical Coherence Tomography (OCT) based on plane-parallel scanning of the illuminating beam, we present a compact but rigorous K-space description in which the spectral representation is us…
View article: Optimization of Preliminary Vector Averaging for Improving Strain-Estimation Accuracy in Phase-Sensitive Optical Coherence Elastography
Optimization of Preliminary Vector Averaging for Improving Strain-Estimation Accuracy in Phase-Sensitive Optical Coherence Elastography Open
In this paper we present a method that significantly improves strain estimation quality in phase-sensitive optical coherence elastography (OCE), in which interframe strains are proportional to gradients of interframe phase variations. The …
View article: Side-by-Side OCE-Study of Elasticity and SHG-Characterization of Collagen Fibers in Breast Cancer Tissue before and after Chemotherapy
Side-by-Side OCE-Study of Elasticity and SHG-Characterization of Collagen Fibers in Breast Cancer Tissue before and after Chemotherapy Open
In the recent years promising results have been shown by the use of Compression optical coherence elastography (C-OCE) as a new optical biopsy approach to morphological assessment/diagnostics of human breast cancer using differences in ela…
View article: Compression OCT-elastography combined with speckle-contrast analysis as an approach to the morphological assessment of breast cancer tissue
Compression OCT-elastography combined with speckle-contrast analysis as an approach to the morphological assessment of breast cancer tissue Open
Currently, optical biopsy technologies are being developed for rapid and label-free visualization of biological tissue with micrometer-level resolution. They can play an important role in breast-conserving surgery guidance, detection of re…
View article: Spatio-Temporal Dynamics of Diffusion-Associated Deformations of Biological Tissues and Polyacrylamide Gels Observed with Optical Coherence Elastography
Spatio-Temporal Dynamics of Diffusion-Associated Deformations of Biological Tissues and Polyacrylamide Gels Observed with Optical Coherence Elastography Open
In this work, we use the method of optical coherence elastography (OCE) to enable quantitative, spatially resolved visualization of diffusion-associated deformations in the areas of maximum concentration gradients during diffusion of hyper…
View article: Numerical Study of Supra-Wavelength Axial Motion Compensation in Contact-Mode Optical Coherence Angiography Using Fourier-Shift Procedures
Numerical Study of Supra-Wavelength Axial Motion Compensation in Contact-Mode Optical Coherence Angiography Using Fourier-Shift Procedures Open
Label-free angiographic methods based on optical coherence tomography (OCT) visualize blood vessels utilizing detection of red blood cells motion against surrounding static tissue. However, in practice, the surrounding tissue is never stil…
View article: Mapping Large Strains in Phase-Sensitive OCT: Key Role of Supra-Pixel Displacement Tracking in Incremental Strain Evaluation
Mapping Large Strains in Phase-Sensitive OCT: Key Role of Supra-Pixel Displacement Tracking in Incremental Strain Evaluation Open
Displacement tracking is an important step in realization of compression optical coherence elastography (C-OCE), especially in the context of obtaining nonlinear stress-strain dependences and subsequent evaluation of the tissue Young's mod…
View article: Novel Elastography-Inspired Approach to Angiographic Visualization in Optical Coherence Tomography
Novel Elastography-Inspired Approach to Angiographic Visualization in Optical Coherence Tomography Open
In this paper, we present a new approach to contrast-agent-free angiographic visualization in optical coherence tomography (OCT). The proposed approach has much in common with imaging of local interframe strains in OCT-based elastography a…
View article: Nonlinear Elasticity Assessment with Optical Coherence Elastography for High-Selectivity Differentiation of Breast Cancer Tissues
Nonlinear Elasticity Assessment with Optical Coherence Elastography for High-Selectivity Differentiation of Breast Cancer Tissues Open
Soft biological tissues, breast cancer tissues in particular, often manifest pronounced nonlinear elasticity, i.e., strong dependence of their Young’s modulus on the applied stress. We showed that compression optical coherence elastography…
View article: Compression optical coherence elastography versus strain ultrasound elastography for breast cancer detection and differentiation: pilot study
Compression optical coherence elastography versus strain ultrasound elastography for breast cancer detection and differentiation: pilot study Open
The aims of this study are (i) to compare ultrasound strain elastography (US-SE) and compression optical coherence elastography (C-OCE) in characterization of elastically linear phantoms, (ii) to evaluate factors that can cause discrepancy…
View article: Optical Coherence Elastography as a Tool for Studying Deformations in Biomaterials: Spatially-Resolved Osmotic Strain Dynamics in Cartilaginous Samples
Optical Coherence Elastography as a Tool for Studying Deformations in Biomaterials: Spatially-Resolved Osmotic Strain Dynamics in Cartilaginous Samples Open
This paper presents a recently developed variant of phase-resolved Optical Coherence Elastography (OCE) enabling non-contact visualization of transient local strains of various origins in biological tissues and other materials. In this wor…
View article: Real-Time Strain and Elasticity Imaging in Phase-Sensitive Optical Coherence Elastography Using a Computationally Efficient Realization of the Vector Method
Real-Time Strain and Elasticity Imaging in Phase-Sensitive Optical Coherence Elastography Using a Computationally Efficient Realization of the Vector Method Open
We present a real-time realization of OCT-based elastographic mapping local strains and distribution of the Young’s modulus in biological tissues, which is in high demand for biomedical usage. The described variant exploits the principle o…
View article: Flexible Computationally Efficient Platform for Simulating Scan Formation in Optical Coherence Tomography with Accounting for Arbitrary Motions of Scatterers
Flexible Computationally Efficient Platform for Simulating Scan Formation in Optical Coherence Tomography with Accounting for Arbitrary Motions of Scatterers Open
A computationally efficient and fairly realistic model of OCT-scan formation in spectral-domain optical coherence tomography is described. The model is based on the approximation of discrete scatterers and ballistic character of scattering…
View article: Diagnostic Accuracy of Cross-Polarization OCT and OCT-Elastography for Differentiation of Breast Cancer Subtypes: Comparative Study
Diagnostic Accuracy of Cross-Polarization OCT and OCT-Elastography for Differentiation of Breast Cancer Subtypes: Comparative Study Open
The possibility to assess molecular-biological and morphological features of particular breast cancer types can improve the precision of resection margin detection and enable accurate determining of the tumor aggressiveness, which is impor…
View article: Quantitative Mapping of Strains and Young Modulus Based on Phase-Sensitive OCT
Quantitative Mapping of Strains and Young Modulus Based on Phase-Sensitive OCT Open
In this chapter we consider mapping of local strains and tissue elasticity in optical coherence tomography (OCT) based on analysis of phase-sensitive OCT scans. Conventional structural OCT scans correspond to spatially resolved mapping of …
View article: In vivo assessment of functional and morphological alterations in tumors under treatment using OCT-angiography combined with OCT-elastography
In vivo assessment of functional and morphological alterations in tumors under treatment using OCT-angiography combined with OCT-elastography Open
Emerging methods of anti-tumor therapies require new approaches to tumor response evaluation, especially enabling label-free diagnostics and in vivo utilization. Here, to assess the tumor early reaction and predict its long-term response, …
View article: Method for<i>in vivo</i>assessment of cancer tissue inhomogeneity and accurate histology-like morphological segmentation based on Optical Coherence Elastography
Method for<i>in vivo</i>assessment of cancer tissue inhomogeneity and accurate histology-like morphological segmentation based on Optical Coherence Elastography Open
We present a non-invasive method based on Optical Coherence Elastography (OCE) enabling the in vivo segmentation of morphological tissue constituents, in particular, monitoring of morphological alterations during both tumor development and…
View article: Analysis of low-scattering regions in optical coherence tomography: applications to neurography and lymphangiography
Analysis of low-scattering regions in optical coherence tomography: applications to neurography and lymphangiography Open
Analysis of semi-transparent low scattering biological structures in optical coherence tomography (OCT) has been actively pursued in the context of lymphatic imaging, with most approaches relying on the relative absence of signal as a mean…
View article: OCT-elastography-based optical biopsy for breast cancer delineation and express assessment of morphological/molecular subtypes
OCT-elastography-based optical biopsy for breast cancer delineation and express assessment of morphological/molecular subtypes Open
Application of compressional optical coherence elastography (OCE) for delineation of tumor and peri-tumoral tissue with simultaneous assessment of morphological/molecular subtypes of breast cancer is reported. The approach is based on the …
View article: Optical Coherence Elastography for Non-Invasive Monitoring of Tumor Elasticity under Chemotherapy: Pilot Study
Optical Coherence Elastography for Non-Invasive Monitoring of Tumor Elasticity under Chemotherapy: Pilot Study Open
The aim of the study was to evaluate a novel non-invasive method -optical coherence elastography (OCE) -for detecting early changes in the elasticity of tumor tissue in response to chemotherapy.Materials and Methods.Female BalB/C mice were…
View article: Front Matter: Volume 10831
Front Matter: Volume 10831 Open
A unique citation identifier (CID) number is assigned to each article at the time of publication.Utilization of CIDs allows articles to be
View article: Practical obstacles and their mitigation strategies in compressional optical coherence elastography of biological tissues
Practical obstacles and their mitigation strategies in compressional optical coherence elastography of biological tissues Open
In this paper, we point out some practical obstacles arising in realization of compressional optical coherence elastography (OCE) that have not attracted sufficient attention previously. Specifically, we discuss (i) complications in quanti…