Alexander Pyronneau
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View article: Elevated ERK/p90 ribosomal S6 kinase activity underlies audiogenic seizure susceptibility in fragile X mice
Elevated ERK/p90 ribosomal S6 kinase activity underlies audiogenic seizure susceptibility in fragile X mice Open
Significance Fragile X syndrome is the most common heritable cause of intellectual disability and autism. Elevated protein synthesis is considered a major contributor to the pathophysiology of fragile X. ERK (extracellular signal-regulated…