Alexander Roeder
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Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety Open
Aging of skin is an intricate biological process consisting of two types. While intrinsic or chronological aging is an inevitable process, photoaging involves the premature aging of skin occurring due to cumulative exposure to ultraviolet …
Safety and Efficacy of Fluticasone Propionate in the Topical Treatment of Skin Diseases Open
Fluticasone propionate – the first carbothioate corticosteroid – has been classified as a potent anti-inflammatory drug for dermatological use. It is available as 0.05% cream and 0.005% ointment formulations for the acute and maintenance t…
Induction of Nuclear Factor–κB and c‐Jun/Activator Protein–1 via Toll‐Like Receptor 2 in Macrophages by Antimycotic‐Treated<i>Candida albicans</i> Open
We examined the role of Toll-like receptors (TLRs) by using TLR2-deficient (TLR2(-/-)), TLR4-defective (TLR4(d/d)), and double-knockout murine macrophages and human embryonic kidney (HEK) 293 cells transfected with human TLR2 or TLR4 expre…
Toll-like receptors as key mediators in innate antifungal immunity Open
The Toll protein of Drosophila is a transmembrane receptor involved in dorsoventral polarization during embryonic development and recognition of infection. In mammals, Toll-like receptors (TLRs) constitute a novel protein family involved i…