Alexander Witkowski
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View article: Clinical utility of a digital dermoscopy image-based artificial intelligence device in the diagnosis and management of skin cancer by dermatology health care providers, primary care providers, and nondermatology specialized physicians
Clinical utility of a digital dermoscopy image-based artificial intelligence device in the diagnosis and management of skin cancer by dermatology health care providers, primary care providers, and nondermatology specialized physicians Open
Background: Patients with skin lesions suspicious of skin cancer or atypical nevi frequently present to dermatology health care providers (DHPs), primary care providers (PCPs), and nondermatology specialized physicians (NDSPs) who have var…
View article: Oregon primary care providers as a frontline defense in the War on Melanoma™: improving access to melanoma education
Oregon primary care providers as a frontline defense in the War on Melanoma™: improving access to melanoma education Open
Melanoma is one of the deadliest forms of skin cancer but is typically cured with surgical excision when detected early. As an access point to medical care, primary care providers (PCP) play an integral role in early skin cancer detection.…
View article: Melanoma toolkit for early detection for primary care clinicians: a 1-year follow-up on outcomes
Melanoma toolkit for early detection for primary care clinicians: a 1-year follow-up on outcomes Open
Introduction Primary care providers or clinicians (PCPs) have the potential to assist dermatologists in screening patients at risk for skin cancer, but require training to appropriately identify higher-risk patients, perform skin checks, r…
View article: Clinical Utility of a Digital Dermoscopy Image-Based Artificial Intelligence Device in the Diagnosis and Management of Skin Cancer by Dermatologists
Clinical Utility of a Digital Dermoscopy Image-Based Artificial Intelligence Device in the Diagnosis and Management of Skin Cancer by Dermatologists Open
Background: Patients with skin lesions suspicious for skin cancer or atypical melanocytic nevi of uncertain malignant potential often present to dermatologists, who may have variable dermoscopy triage clinical experience. Objective: To eva…
View article: Revolutionizing Skin Cancer Triage: The Role of Patient-Initiated Teledermoscopy in Remote Diagnosis
Revolutionizing Skin Cancer Triage: The Role of Patient-Initiated Teledermoscopy in Remote Diagnosis Open
Introduction: Teledermatology, defined as the use of remote imaging technologies to provide dermatologic healthcare services to individuals in a distant setting, has grown considerably in popularity since its widespread implementation duri…
View article: Enhancing Diagnosis through AI-driven Analysis of Reflectance Confocal Microscopy
Enhancing Diagnosis through AI-driven Analysis of Reflectance Confocal Microscopy Open
Reflectance Confocal Microscopy (RCM) is a non-invasive imaging technique used in biomedical research and clinical dermatology. It provides virtual high-resolution images of the skin and superficial tissues, reducing the need for physical …
View article: A clinical impact study of dermatologists' use of diagnostic gene expression profile testing to guide patient management
A clinical impact study of dermatologists' use of diagnostic gene expression profile testing to guide patient management Open
Aim: Cutaneous melanocytic neoplasms with diagnostic and/or clinical ambiguity pose patient management challenges. Methods: Six randomized case scenarios with diagnostic/clinical uncertainty were described with/without a benign or malignan…
View article: Enhancing diagnosis through AI-driven analysis of reflectance confocal microscopy
Enhancing diagnosis through AI-driven analysis of reflectance confocal microscopy Open
Reflectance Confocal Microscopy (RCM) is a non-invasive imaging technique used in biomedical research and clinical dermatology. It provides virtual high-resolution images of the skin and superficial tissues, reducing the need for physical …
View article: Artificial Intelligence Applied to Non-Invasive Imaging Modalities in Identification of Nonmelanoma Skin Cancer: A Systematic Review
Artificial Intelligence Applied to Non-Invasive Imaging Modalities in Identification of Nonmelanoma Skin Cancer: A Systematic Review Open
Background: The objective of this study is to systematically analyze the current state of the literature regarding novel artificial intelligence (AI) machine learning models utilized in non-invasive imaging for the early detection of nonme…
View article: Sequential Dermoscopy and Reflectance Confocal Microscopy Paired With Pigmented Lesion Assay Gene Expression Profiling for In Vivo Monitoring of Multiple Halo Nevi on an Adult Patient
Sequential Dermoscopy and Reflectance Confocal Microscopy Paired With Pigmented Lesion Assay Gene Expression Profiling for In Vivo Monitoring of Multiple Halo Nevi on an Adult Patient Open
The halo nevus is characterized by a ring of depigmentation appearing around an acquired or congenital melanocytic nevus. When observed in children, halo nevi are generally not a cause of concern. However, adult-onset halo nevi have an ass…
View article: Analysis of Artificial Intelligence-Based Approaches Applied to Non-Invasive Imaging for Early Detection of Melanoma: A Systematic Review
Analysis of Artificial Intelligence-Based Approaches Applied to Non-Invasive Imaging for Early Detection of Melanoma: A Systematic Review Open
Background: Melanoma, the deadliest form of skin cancer, poses a significant public health challenge worldwide. Early detection is crucial for improved patient outcomes. Non-invasive skin imaging techniques allow for improved diagnostic ac…
View article: A Physician's Guide to the Use of Gene Expression Profile Ancillary Diagnostic Testing for Cutaneous Melanocytic Neoplasms.
A Physician's Guide to the Use of Gene Expression Profile Ancillary Diagnostic Testing for Cutaneous Melanocytic Neoplasms. Open
Open communication between dermatopathologists and dermatologists, especially regarding GEP testing, can be a vital component to achieve appropriate clinicopathologic correlation for otherwise ambiguous melanocytic lesions.
View article: Dermoscopic features associated with 3‐GEP PLA: LINC00518, PRAME, and TERT expression in suspicious pigmented lesions
Dermoscopic features associated with 3‐GEP PLA: LINC00518, PRAME, and TERT expression in suspicious pigmented lesions Open
Utilization of dermoscopy and novel molecular triage technologies augments visual triage of pigmented skin lesions, promoting early detection of melanoma. One emerging in vivo genomic test, 3‐GEP pigmented lesion assay (3‐GEP PLA) aids in …
View article: Expert Consensus Statement on Proficiency Standards for Dermoscopy Education in Primary Care
Expert Consensus Statement on Proficiency Standards for Dermoscopy Education in Primary Care Open
This consensus statement will inform the development of PCP-targeted dermoscopy training initiatives designed to support early cancer detection.
View article: Dermoscopy and Reflectance Confocal Microscopy of Apocrine Hidrocystoma
Dermoscopy and Reflectance Confocal Microscopy of Apocrine Hidrocystoma Open
Citation: Ludzik J, Lee C, Mengden S, Nguyen H, Pleshakov D, Witkowski A. Dermoscopy and Reflectance Confocal Microscopy of Apocrine Hidrocystoma. Dermatol Pract Concept. 2023;13(1):e2023039. DOI: https://doi.org/10.5826/dpc.1301a39
View article: Combined Use of Dermoscopy, Reflectance Confocal Microscopy, and Ex-Vivo Gene Expression Profiling to Detect a Micromelanoma Less Than 1 mm in Diameter
Combined Use of Dermoscopy, Reflectance Confocal Microscopy, and Ex-Vivo Gene Expression Profiling to Detect a Micromelanoma Less Than 1 mm in Diameter Open
.Micro-melanomas, or melanomas < 2 mm in diameter, are increasingly reported making screening methods like the ABCD(E) acronym outdated. Early detection of melanoma remains the utmost important prognostic factor, therefore understanding…
View article: Analyzing Differences in Diagnostic Accuracy of a Pigmented Lesion Assay for Melanoma
Analyzing Differences in Diagnostic Accuracy of a Pigmented Lesion Assay for Melanoma Open
Background . Standard protocol to detect melanoma relies on visual assessment in which the sensitivity and specificity are low for early melanomas. Pigmented lesion assay (PLA) offers objective metrics to aid in determining suspicious lesi…
View article: Urban versus rural utilization of teledermoscopy in self-skin examinations: preliminary results of a cohort study in the states of Oregon and Washington
Urban versus rural utilization of teledermoscopy in self-skin examinations: preliminary results of a cohort study in the states of Oregon and Washington Open
In this letter, we examine the application of smartphone dermoscopy in teledermatology skin cancer screenings for individuals in rural communities. There is currently a paucity of literature that examines teledermoscopy in rural areas of t…
View article: Inequities in geriatric access to teledermatology and smartphone dermoscopy
Inequities in geriatric access to teledermatology and smartphone dermoscopy Open
With the rising number of dermatology visits being completed via virtual pathways, the sharing of high-quality images between patient and provider is vital. Smartphone dermoscopy is an emerging technology that when paired with store-and-fo…
View article: Dermoscopy and reflectance confocal microscopy‐augmented characterization of pigmented micro‐basal cell carcinoma (less than 2 mm diameter)
Dermoscopy and reflectance confocal microscopy‐augmented characterization of pigmented micro‐basal cell carcinoma (less than 2 mm diameter) Open
Background Basal cell carcinoma (BCC) is the most common skin cancer, accounting for approximately 80% of nonmelanoma skin cancer diagnoses each year. Among other factors, the staging of BCC is influenced by its measured diameter. Stage 1 …
View article: The role of mobile teledermoscopy in skin cancer triage and management during the COVID-19 pandemic
The role of mobile teledermoscopy in skin cancer triage and management during the COVID-19 pandemic Open
The unprecedented onset of the COVID-19 crisis poses a significant challenge to all fields of medicine, including dermatology. Since the start of the coronavirus outbreak, a stark decline in new skin cancer diagnoses has been reported by c…
View article: Clinical Utility of Dermoscopy and 31-Gene Expression Profiling by Dermatology Providers in Melanoma Management Care
Clinical Utility of Dermoscopy and 31-Gene Expression Profiling by Dermatology Providers in Melanoma Management Care Open
This study represents our experience and understanding of the dermatologist’s role ordering 31-GEP in the care pathway of melanoma patients and we recommend that dermatology providers consider ordering the test for newly diagnosed CMM pati…
View article: Augmenting pigmented lesion assay results with the three‐point dermoscopy checklist to improve pigmented lesion triage
Augmenting pigmented lesion assay results with the three‐point dermoscopy checklist to improve pigmented lesion triage Open
The estimated cost to the healthcare system to detect one melanoma is approximately $32594, which is largely due to the high biopsy rate of benign lesions.1 One systematic review and meta-analysis found that the number needed to treat to i…
View article: Dermoscopy of Gottron’s papules and other inflammatory dermatoses involving the dorsa of the hands
Dermoscopy of Gottron’s papules and other inflammatory dermatoses involving the dorsa of the hands Open
Background Several inflammatory dermatoses, including dermatomyositis (DM), may present as erythematous papules or plaques on the dorsal aspects of the hands over the joints. Limited skin involvement in these entities may pose a diagnostic…
View article: Novel Ink - Stained Reflectance Confocal Microscopy Guided Pigmented Skin Lesion Biopsy Technique: Reducing Pathology Sample Bias Through Improved Precision
Novel Ink - Stained Reflectance Confocal Microscopy Guided Pigmented Skin Lesion Biopsy Technique: Reducing Pathology Sample Bias Through Improved Precision Open
With skin cancer incidence rate steadily increasing each year, melanoma continues to pose a significant public health problem globally. It is well-known that early detection and prevention of melanoma remains the most important interventio…