Alexandra Dreyfuss
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View article: A multicenter real-world analysis of combined chemotherapy followed by consolidative radiation versus chemotherapy alone in the management of early-stage Hodgkin lymphoma – the HODGKIN25 study
A multicenter real-world analysis of combined chemotherapy followed by consolidative radiation versus chemotherapy alone in the management of early-stage Hodgkin lymphoma – the HODGKIN25 study Open
Intro Early-stage classical Hodgkin lymphoma (cHL) is a highly curable malignancy. Traditionally, patients (pts) have been treated with combined modality therapy (CMT) using A(B)VD +/- consolidative radiotherapy (RT). Given potential toxic…
View article: RADT-86. NEUROANATOMICAL AND MOLECULAR FEATURES OF SECONDARY CNS LYMPHOMA INFLUENCE THE PATTERNS OF CNS FAILURE AFTER SALVAGE RADIOTHERAPY
RADT-86. NEUROANATOMICAL AND MOLECULAR FEATURES OF SECONDARY CNS LYMPHOMA INFLUENCE THE PATTERNS OF CNS FAILURE AFTER SALVAGE RADIOTHERAPY Open
INTRODUCTION Radiotherapy (RT) is a potential salvage treatment for secondary central nervous system lymphoma (SCNSL), but its optimal use is not well-defined. We analyzed response and failure patterns after salvage RT. METHODS We identifi…
View article: RADT-84. LOW-DOSE WHOLE BRAIN RADIOTHERAPY AS AN EFFECTIVE CONSOLIDATION STRATEGY IN SECONDARY CENTRAL NERVOUS SYSTEM LYMPHOMA
RADT-84. LOW-DOSE WHOLE BRAIN RADIOTHERAPY AS AN EFFECTIVE CONSOLIDATION STRATEGY IN SECONDARY CENTRAL NERVOUS SYSTEM LYMPHOMA Open
INTRODUCTION Optimal consolidation strategies for secondary central nervous system lymphoma (SCNSL) are not well defined. Autologous stem cell transplant (ASCT) has shown promise, but alternatives are needed for ASCT-ineligible patients. W…
View article: Bridging Radiation Durably Controls Patients with Bulky Tumors Treated with CAR-T Cell Therapy
Bridging Radiation Durably Controls Patients with Bulky Tumors Treated with CAR-T Cell Therapy Open
View article: 405 | TRENDS IN THE INCORPORATION OF RADIOTHERAPY IN THE MANAGEMENT OF MULTIPLE MYELOMA OVER THE PAST DECADE: HIGH LOCAL CONTROL RATE AND FACTORS ASSOCIATED WITH ITS DURABILITY
405 | TRENDS IN THE INCORPORATION OF RADIOTHERAPY IN THE MANAGEMENT OF MULTIPLE MYELOMA OVER THE PAST DECADE: HIGH LOCAL CONTROL RATE AND FACTORS ASSOCIATED WITH ITS DURABILITY Open
View article: 451 | MYC ALTERATIONS CONFER WORSE LOCAL CONTROL IN PATIENTS UNDERGOING BRIDGING RADIOTHERAPY PRIOR TO CAR‐T
451 | MYC ALTERATIONS CONFER WORSE LOCAL CONTROL IN PATIENTS UNDERGOING BRIDGING RADIOTHERAPY PRIOR TO CAR‐T Open
View article: 395 | TOTAL SKIN ELECTRON BEAM THERAPY FOR MYCOSIS FUNGOIDES IN THE MODERN ERA OF TSEBT DOSE REDUCTION AND DIVERSIFIED SYSTEMIC THERAPY
395 | TOTAL SKIN ELECTRON BEAM THERAPY FOR MYCOSIS FUNGOIDES IN THE MODERN ERA OF TSEBT DOSE REDUCTION AND DIVERSIFIED SYSTEMIC THERAPY Open
View article: 129 | PEMBROLIZUMAB AND RADIATION THERAPY ALONE AS AN ALTERNATIVE TO TRANSPLANT FOR LOCALIZED FAILURE AFTER CHEMOTHERAPY IN HODGKIN LYMPHOMA: A MULTICENTER PHASE II STUDY
129 | PEMBROLIZUMAB AND RADIATION THERAPY ALONE AS AN ALTERNATIVE TO TRANSPLANT FOR LOCALIZED FAILURE AFTER CHEMOTHERAPY IN HODGKIN LYMPHOMA: A MULTICENTER PHASE II STUDY Open
View article: 25 | RESPONSE‐ADAPTED VERY LOW DOSE RADIOTHERAPY (RA‐VLDRT) FOR POTENTIALLY CURABLE INDOLENT NON‐HODGKIN LYMPHOMA
25 | RESPONSE‐ADAPTED VERY LOW DOSE RADIOTHERAPY (RA‐VLDRT) FOR POTENTIALLY CURABLE INDOLENT NON‐HODGKIN LYMPHOMA Open
View article: 452 | BRIDGING RADIOTHERAPY DOES NOT INCREASE RISK OF CAR T‐CELL ASSOCIATED TOXICITY
452 | BRIDGING RADIOTHERAPY DOES NOT INCREASE RISK OF CAR T‐CELL ASSOCIATED TOXICITY Open
View article: 407 | RADIATION THERAPY FOR OLIGO‐RELAPSED/PROGRESSIVE DISEASE POST‐STEM CELL TRANSPLANT FOR MULTIPLE MYELOMA: FACTORS ASSOCIATED WITH FAVORABLE OUTCOMES
407 | RADIATION THERAPY FOR OLIGO‐RELAPSED/PROGRESSIVE DISEASE POST‐STEM CELL TRANSPLANT FOR MULTIPLE MYELOMA: FACTORS ASSOCIATED WITH FAVORABLE OUTCOMES Open
View article: 108 | LOCAL CONTROL WITH RESPONSE‐ADAPTED VERY LOW DOSE RADIOTHERAPY (RA‐VLDRT) OF 4 GY FOR INDOLENT NON‐HODGKIN LYMPHOMA
108 | LOCAL CONTROL WITH RESPONSE‐ADAPTED VERY LOW DOSE RADIOTHERAPY (RA‐VLDRT) OF 4 GY FOR INDOLENT NON‐HODGKIN LYMPHOMA Open
View article: 717 | LEPTOMENINGEAL DISEASE IS ASSOCIATED WITH MYC CHROMOSOMAL ALTERATIONS AND WORSE OVERALL SURVIVAL AMONG SECONDARY CNS LYMPHOMA PATIENTS TREATED WITH SALVAGE RADIOTHERAPY
717 | LEPTOMENINGEAL DISEASE IS ASSOCIATED WITH MYC CHROMOSOMAL ALTERATIONS AND WORSE OVERALL SURVIVAL AMONG SECONDARY CNS LYMPHOMA PATIENTS TREATED WITH SALVAGE RADIOTHERAPY Open
View article: 413 | PROGRESSION PATTERNS BY POSITRON EMISSION TOMOGRAPHY FOR RELAPSED/REFRACTORY MULTIPLE MYELOMA AFTER CAR T CELL THERAPY: POTENTIAL ROLE FOR RADIOTHERAPY?
413 | PROGRESSION PATTERNS BY POSITRON EMISSION TOMOGRAPHY FOR RELAPSED/REFRACTORY MULTIPLE MYELOMA AFTER CAR T CELL THERAPY: POTENTIAL ROLE FOR RADIOTHERAPY? Open
View article: Rectal Spacer Placement for Anorectal Reirradiation of De Novo Rectal or Anal Cancer Following Prostate Radiation Therapy
Rectal Spacer Placement for Anorectal Reirradiation of De Novo Rectal or Anal Cancer Following Prostate Radiation Therapy Open
Background: Pelvic reirradiation of de novo rectal or anal cancer after prior prostate cancer RT poses a significant risk of urinary and rectal fistula. In this report we describe the use of a rectal spacer to improve dosimetry and reduce …
View article: A Prospective Phase I/II Clinical Trial of High-Dose Proton Therapy for Chordomas and Chondrosarcomas
A Prospective Phase I/II Clinical Trial of High-Dose Proton Therapy for Chordomas and Chondrosarcomas Open
View article: Prospective Evaluation of MRI-Based Endoluminal Brachytherapy with Novel Applicator for Anorectal Cancer
Prospective Evaluation of MRI-Based Endoluminal Brachytherapy with Novel Applicator for Anorectal Cancer Open
View article: Salvage Radiotherapy as a Bridge for Relapsed Secondary CNS Lymphoma
Salvage Radiotherapy as a Bridge for Relapsed Secondary CNS Lymphoma Open
View article: UPFRONT RADIATION THERAPY FOR POST‐STEM CELL TRANSPLANT MULTIPLE MYELOMA PATIENTS WITH OLIGO‐RELAPSE/PROGRESSIVE DISEASE: FACTORS ASSOCIATED WITH FAVORABLE OUTCOMES
UPFRONT RADIATION THERAPY FOR POST‐STEM CELL TRANSPLANT MULTIPLE MYELOMA PATIENTS WITH OLIGO‐RELAPSE/PROGRESSIVE DISEASE: FACTORS ASSOCIATED WITH FAVORABLE OUTCOMES Open
Introduction: MM patients (pts) remaining refractory or presenting with a relapse after stem cell transplant (SCT) may have a dismal prognosis. Yet, RT may still provide an effective tool for control of localized disease. We report on the …
View article: Radiotherapy as an effective bridge for chemo‐refractory or progressive secondary CNS lymphoma
Radiotherapy as an effective bridge for chemo‐refractory or progressive secondary CNS lymphoma Open
Introduction: Secondary CNS lymphoma (SCNSL) is observed in 2%–5% of patients with diffuse large B cell lymphoma (DLBCL). Progression of SCNSL after first line CNS-directed systemic therapy is particularly challenging, without clear standa…
View article: Radiation in a new era of Multiple Myeloma management: Patterns of utilization, clinical, radiologic, and biochemical outcomes, and possible genomic correlates of response
Radiation in a new era of Multiple Myeloma management: Patterns of utilization, clinical, radiologic, and biochemical outcomes, and possible genomic correlates of response Open
Background/Objectives: Systemic therapies for multiple myeloma (MM) have advanced considerably, improving patient outcomes. Yet, the use of radiotherapy (RT) has remained heterogeneous, and even controversial, due to minimal data on outcom…
View article: Hypofractionated Radiation Therapy (Hypo-RT) for the Treatment of Localized Bladder Cancer
Hypofractionated Radiation Therapy (Hypo-RT) for the Treatment of Localized Bladder Cancer Open
BACKGROUND: Various radiotherapeutic regimens are used in the treatment of bladder cancer. OBJECTIVE: We aimed to evaluate early toxicity and outcomes associated with hypofractionated radiation therapy (Hypo-RT), 55Gy in 20 fractions. MATE…
View article: Locoregional Control Benefit of a Tumor Bed Boost for Ductal Carcinoma In Situ
Locoregional Control Benefit of a Tumor Bed Boost for Ductal Carcinoma In Situ Open
Among patients with DCIS who underwent BCS, use of a tumor bed boost was not associated with locoregional recurrence or RFS. Despite a preponderance of adverse features among the boost cohort, outcomes were similar to those of patients not…
View article: Supplementary Data from A Novel Mouse Model of Radiation-Induced Cardiac Injury Reveals Biological and Radiological Biomarkers of Cardiac Dysfunction with Potential Clinical Relevance
Supplementary Data from A Novel Mouse Model of Radiation-Induced Cardiac Injury Reveals Biological and Radiological Biomarkers of Cardiac Dysfunction with Potential Clinical Relevance Open
Supplementary materials and figures
View article: Data from A Novel Mouse Model of Radiation-Induced Cardiac Injury Reveals Biological and Radiological Biomarkers of Cardiac Dysfunction with Potential Clinical Relevance
Data from A Novel Mouse Model of Radiation-Induced Cardiac Injury Reveals Biological and Radiological Biomarkers of Cardiac Dysfunction with Potential Clinical Relevance Open
Purpose:Radiation-induced cardiotoxicity is a significant concern in thoracic oncology patients. However, the basis for this disease pathology is not well characterized. We developed a novel mouse model of radiation-induced cardiotoxicity …
View article: Supplementary Data from A Novel Mouse Model of Radiation-Induced Cardiac Injury Reveals Biological and Radiological Biomarkers of Cardiac Dysfunction with Potential Clinical Relevance
Supplementary Data from A Novel Mouse Model of Radiation-Induced Cardiac Injury Reveals Biological and Radiological Biomarkers of Cardiac Dysfunction with Potential Clinical Relevance Open
Supplementary materials and figures
View article: Supplementary Video S1 from A Novel Mouse Model of Radiation-Induced Cardiac Injury Reveals Biological and Radiological Biomarkers of Cardiac Dysfunction with Potential Clinical Relevance
Supplementary Video S1 from A Novel Mouse Model of Radiation-Induced Cardiac Injury Reveals Biological and Radiological Biomarkers of Cardiac Dysfunction with Potential Clinical Relevance Open
Representative video clips of echocardiography performed in unirradiated and irradiated mice 8 weeks post-RT.
View article: Supplementary Video S1 from A Novel Mouse Model of Radiation-Induced Cardiac Injury Reveals Biological and Radiological Biomarkers of Cardiac Dysfunction with Potential Clinical Relevance
Supplementary Video S1 from A Novel Mouse Model of Radiation-Induced Cardiac Injury Reveals Biological and Radiological Biomarkers of Cardiac Dysfunction with Potential Clinical Relevance Open
Representative video clips of echocardiography performed in unirradiated and irradiated mice 8 weeks post-RT.
View article: Data from A Novel Mouse Model of Radiation-Induced Cardiac Injury Reveals Biological and Radiological Biomarkers of Cardiac Dysfunction with Potential Clinical Relevance
Data from A Novel Mouse Model of Radiation-Induced Cardiac Injury Reveals Biological and Radiological Biomarkers of Cardiac Dysfunction with Potential Clinical Relevance Open
Purpose:Radiation-induced cardiotoxicity is a significant concern in thoracic oncology patients. However, the basis for this disease pathology is not well characterized. We developed a novel mouse model of radiation-induced cardiotoxicity …
View article: Preclinical models of radiation-induced cardiac toxicity: Potential mechanisms and biomarkers
Preclinical models of radiation-induced cardiac toxicity: Potential mechanisms and biomarkers Open
Radiation therapy (RT) is an important modality in cancer treatment with >50% of cancer patients undergoing RT for curative or palliative intent. In patients with breast, lung, and esophageal cancer, as well as mediastinal malignancies,…