Alexandra Mailles
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View article: Adaptive behavior in response to the 2022 mpox epidemic in the Paris region
Adaptive behavior in response to the 2022 mpox epidemic in the Paris region Open
The 2022 mpox outbreak saw a rapid case surge among men-who-have-sex-with-men (MSM) in previously unaffected regions, driven by heterogeneity in sexual networks. A sudden decline followed, but its drivers remain unclear as it is difficult …
View article: Risk of SARS-CoV-2 infection in professional settings, shops, shared transport, and leisure activities in France, 2020–2022
Risk of SARS-CoV-2 infection in professional settings, shops, shared transport, and leisure activities in France, 2020–2022 Open
View article: The French National Animal Health Surveillance Platform: an innovative, cross-sector collaboration to improve surveillance system efficiency in France and a tangible example of the One Health approach
The French National Animal Health Surveillance Platform: an innovative, cross-sector collaboration to improve surveillance system efficiency in France and a tangible example of the One Health approach Open
The French National Animal Health Surveillance Platform (NAHSP) was created in 2011. This network of animal health stakeholders was set up to improve surveillance efficiency for all health risks that threaten animal health, as well as zoon…
View article: Mpox in children and adolescents and contact follow-up in school settings in greater Paris, France, May 2022 to July 2023
Mpox in children and adolescents and contact follow-up in school settings in greater Paris, France, May 2022 to July 2023 Open
Background During the 2022 mpox outbreak in Europe, primarily affecting men who have sex with men, a limited number of cases among children and adolescents were identified. Paediatric cases from outbreaks in endemic countries have been ass…
View article: Characteristics, management and outcome of Herpes Simplex and Varicella-Zoster virus encephalitis: a multicentre prospective cohort study
Characteristics, management and outcome of Herpes Simplex and Varicella-Zoster virus encephalitis: a multicentre prospective cohort study Open
View article: Encephalitis in HIV-negative immunodeficient patients: a prospective multicentre study, France, 2016 to 2019
Encephalitis in HIV-negative immunodeficient patients: a prospective multicentre study, France, 2016 to 2019 Open
Background Data on infectious encephalitis in immunodeficient (ID) individuals are scarce. This population may present with atypical clinical symptoms, be infected by uncommon pathogens and develop poor outcomes. Aim We aimed to describe t…
View article: Source of SARS-CoV-2 infection: results from a series of 584,846 cases in France from October 2020 to August 2022
Source of SARS-CoV-2 infection: results from a series of 584,846 cases in France from October 2020 to August 2022 Open
Background We aimed to study the source of infection for recently SARS-CoV-2-infected individuals from October 2020 to August 2022 in France. Methods Participants from the nationwide ComCor case–control study who reported recent SARS-CoV-2…
View article: Outcome and Sequelae of Infectious Encephalitis
Outcome and Sequelae of Infectious Encephalitis Open
Acute infectious encephalitis is a widely studied clinical syndrome. Although identified almost 100 years ago, its immediate and delayed consequences are still neglected despite their high frequency and possible severity. We reviewed the a…
View article: Outcome and Sequelae of Autoimmune Encephalitis
Outcome and Sequelae of Autoimmune Encephalitis Open
Autoimmune etiologies are a common cause for encephalitis. The clinical syndromes consistent with autoimmune encephalitis are both distinct and increasingly recognized, but less is known about persisting sequelae or outcomes. We searched P…
View article: Mpox outbreak in France: epidemiological characteristics and sexual behaviour of cases aged 15 years or older, 2022
Mpox outbreak in France: epidemiological characteristics and sexual behaviour of cases aged 15 years or older, 2022 Open
Background Locally-acquired mpox cases were rarely reported outside Africa until May 2022, when locally-acquired-mpox cases occurred in various European countries. Aim We describe the mpox epidemic in France, including demographic and beha…
View article: Source of SARS-CoV-2 infection: results from a series of 584,846 cases in France from October 2020 to August 2022
Source of SARS-CoV-2 infection: results from a series of 584,846 cases in France from October 2020 to August 2022 Open
Background We aimed to study the source of infection for recently SARS-CoV-2-infected individuals from October 2020 to August 2022 in France. Methods Participants from the nationwide ComCor case-control study who reported recent SARS-CoV-2…
View article: Risk of SARS-CoV-2 Infection Among Households With Children in France, 2020-2022
Risk of SARS-CoV-2 Infection Among Households With Children in France, 2020-2022 Open
Importance Understanding the contribution of children to SARS-CoV-2 circulation in households is critical for designing public health policies and mitigation strategies. Objective To identify temporal changes in the risk of SARS-CoV-2 infe…
View article: Estimated incubation period distributions of mpox using cases from two international European festivals and outbreaks in a club in Berlin, May to June 2022
Estimated incubation period distributions of mpox using cases from two international European festivals and outbreaks in a club in Berlin, May to June 2022 Open
Background Since May 2022, an mpox outbreak affecting primarily men who have sex with men (MSM) has occurred in numerous non-endemic countries worldwide. As MSM frequently reported multiple sexual encounters in this outbreak, reliably dete…
View article: Reduction of SARS-CoV-2 intra-household child-to-parent transmission associated with ventilation: results from a case–control study
Reduction of SARS-CoV-2 intra-household child-to-parent transmission associated with ventilation: results from a case–control study Open
Purpose Our objective was to describe circumstances of SARS-CoV-2 household transmission and to identify factors associated with a lower risk of transmission in a nationwide case–control study in France. Methods In a descriptive analysis, …
View article: SARS-CoV-2 self-test uptake and factors associated with self-testing during Omicron BA.1 and BA.2 waves in France, January to May 2022
SARS-CoV-2 self-test uptake and factors associated with self-testing during Omicron BA.1 and BA.2 waves in France, January to May 2022 Open
Background Following the SARS-CoV-2 Omicron variant spread, the use of unsupervised antigenic rapid diagnostic tests (self-tests) increased. Aim This study aimed to measure self-test uptake and factors associated with self-testing. Methods…
View article: SARS-CoV-2 incubation period across variants of concern, individual factors, and circumstances of infection in France: a case series analysis from the ComCor study
SARS-CoV-2 incubation period across variants of concern, individual factors, and circumstances of infection in France: a case series analysis from the ComCor study Open
Institut Pasteur, the French National Agency for AIDS Research-Emerging Infectious Diseases, Fondation de France, the INCEPTION project, and the Integrative Biology of Emerging Infectious Diseases project.
View article: Encephalitis in travellers: a prospective multicentre study
Encephalitis in travellers: a prospective multicentre study Open
Background As the epidemiology of encephalitis varies from one country to another, international travel may be an important clue for the diagnostic workout of this puzzling disease. Methods We performed an ancillary study using the ENCEIF …
View article: Reply to: The role of pets in SARS-CoV-2 transmission: an exploratory analysis
Reply to: The role of pets in SARS-CoV-2 transmission: an exploratory analysis Open
View article: Risk of Monkeypox virus (MPXV) transmission through the handling and consumption of food
Risk of Monkeypox virus (MPXV) transmission through the handling and consumption of food Open
View article: Impact of the Omicron variant on SARS-CoV-2 reinfections in France, March 2021 to February 2022
Impact of the Omicron variant on SARS-CoV-2 reinfections in France, March 2021 to February 2022 Open
Since the first reports in summer 2020, SARS-CoV-2 reinfections have raised concerns about the immunogenicity of the virus, which will affect SARS-CoV-2 epidemiology and possibly the burden of COVID-19 on our societies in the future. This …
View article: Impact of SARS-CoV-2 Delta variant on incubation, transmission settings and vaccine effectiveness: Results from a nationwide case-control study in France
Impact of SARS-CoV-2 Delta variant on incubation, transmission settings and vaccine effectiveness: Results from a nationwide case-control study in France Open
In line with other observational studies, we find reduced vaccine effectiveness against symptomatic Delta infections. The settings and activities at increased risk of infection indicate where efforts to reinforce individual and public heal…
View article: Impact of original, B.1.1.7, and B.1.351/P.1 SARS-CoV-2 lineages on vaccine effectiveness of two doses of COVID-19 mRNA vaccines: Results from a nationwide case-control study in France
Impact of original, B.1.1.7, and B.1.351/P.1 SARS-CoV-2 lineages on vaccine effectiveness of two doses of COVID-19 mRNA vaccines: Results from a nationwide case-control study in France Open
View article: Exposures associated with SARS-CoV-2 infection in France: A nationwide online case-control study
Exposures associated with SARS-CoV-2 infection in France: A nationwide online case-control study Open
View article: Etude des facteurs sociodémographiques, comportements et pratiques associés à l’infection par le SARS-CoV-2 (ComCor)
Etude des facteurs sociodémographiques, comportements et pratiques associés à l’infection par le SARS-CoV-2 (ComCor) Open
L’étude ComCor, qui couvre à ce jour la période du 1er octobre 2020 au 31 janvier 2021, inclut 77208 participants avec infection aiguë par le SARS-CoV-2, hors personnels soignants (8,2% des personnes contactées par mail par la CNAM). L’étu…
View article: Joint ESCMID, FEMS, IDSA, ISID and SSI position paper on the fair handling of career breaks among physicians and scientists when assessing eligibility for early-career awards
Joint ESCMID, FEMS, IDSA, ISID and SSI position paper on the fair handling of career breaks among physicians and scientists when assessing eligibility for early-career awards Open
View article: First Cases of Coronavirus Disease 2019 (COVID-19) in the WHO European Region, 24 January to 21 February 2020
First Cases of Coronavirus Disease 2019 (COVID-19) in the WHO European Region, 24 January to 21 February 2020 Open
In the WHO European Region, COVID-19 surveillance was implemented 27 January 2020. We detail the first European cases. As at 21 February, nine European countries reported 47 cases. Among 38 cases studied, 21 were linked to two clusters in …
View article: Early chains of transmission of COVID-19 in France
Early chains of transmission of COVID-19 in France Open
Introduction SARS-CoV-2, which causes COVID-19, has spread rapidly across the world. A dedicated surveillance system was implemented in France in January 2020 to improve early detection of cases and their contacts and limit secondary trans…
View article: Prevention of human rabies: a challenge for the European Union and the European Economic Area
Prevention of human rabies: a challenge for the European Union and the European Economic Area Open
Rabies is enzootic in over one hundred countries worldwide. In the European Union/European Economic Area (EU/EEA), the vast majority of human rabies cases are travellers bitten by dogs in rabies-enzootic countries, mostly in Asia and Afric…
View article: Cluster of Coronavirus Disease 2019 (COVID-19) in the French Alps, February 2020
Cluster of Coronavirus Disease 2019 (COVID-19) in the French Alps, February 2020 Open
Background On 7 February 2020, French Health authorities were informed of a confirmed case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in an Englishman infected in Singapore who had recently stayed in a chalet in the Fr…
View article: Clinical and virological data of the first cases of COVID-19 in Europe: a case series
Clinical and virological data of the first cases of COVID-19 in Europe: a case series Open
REACTing (Research & Action Emerging Infectious Diseases).