Alexandra P. Steele
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View article: Insulin Prevents Fat Loss and Promotes Muscle Loss During Intermittent Fasting in Obesity
Insulin Prevents Fat Loss and Promotes Muscle Loss During Intermittent Fasting in Obesity Open
Elevated blood glucose, insulin, and insulin resistance are associated with obesity and type 2 diabetes (T2D). High blood insulin levels blunt lipolysis and promote lipogenesis, and thus weight gain. Intermittent fasting (IF) has emerged a…
View article: Whole body resistance training on functional outcomes of patients with Stage 4 or 5 chronic kidney disease: A systematic review
Whole body resistance training on functional outcomes of patients with Stage 4 or 5 chronic kidney disease: A systematic review Open
Chronic kidney disease (CKD) causes skeletal muscle wasting, resulting in reduced function and inability to live independently. This systematic review critically appraised the scientific literature regarding the effects of full‐body resist…
View article: Whole body resistance training on functional outcomes of patients with stage 4 or 5 chronic kidney disease: A protocol for a systematic review
Whole body resistance training on functional outcomes of patients with stage 4 or 5 chronic kidney disease: A protocol for a systematic review Open
View article: Discovery-Based Proteomics Identify Skeletal Muscle Mitochondrial Alterations as an Early Metabolic Defect in a Mouse Model of β-Thalassemia
Discovery-Based Proteomics Identify Skeletal Muscle Mitochondrial Alterations as an Early Metabolic Defect in a Mouse Model of β-Thalassemia Open
Although metabolic complications are common in thalassemia patients, there is still an unmet need to better understand underlying mechanisms. We used unbiased global proteomics to reveal molecular differences between the th3/+ mouse model …