Ana João Rodrigues
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View article: MANEJO ODONTOLÓGICO DE PACIENTES COM DOENÇAS CARDÍACAS ISQUÊMICAS
MANEJO ODONTOLÓGICO DE PACIENTES COM DOENÇAS CARDÍACAS ISQUÊMICAS Open
As cardiopatias isquêmicas, como a angina de peito e o infarto agudo do miocárdio, são causas relevantes de morbimortalidade global e representam um desafio importante e não raro na prática odontológica, sobretudo em procedimentos cirúrgic…
View article: INFLUENCE OF DIFFERENT BONE GRAFTING TECHNIQUES ON PRIMARY STABILITY
INFLUENCE OF DIFFERENT BONE GRAFTING TECHNIQUES ON PRIMARY STABILITY Open
Objective: To critically review the available evidence on the influence of different bone grafting techniques and implant site preparation methods on the primary stability of dental implants. Methods: Narrative review based on randomized c…
View article: hpGRISZ: a high-performance fluorescent biosensor for in vivo imaging of synaptic zinc dynamics
hpGRISZ: a high-performance fluorescent biosensor for in vivo imaging of synaptic zinc dynamics Open
Despite the crucial role of synaptic Zn 2+ in neurotransmission and neural processing, direct in vivo measurement of Zn 2+ transients has remained challenging due to the limited responsiveness of existing fluorescent indicators. Here we re…
View article: Influência de diferentes técnicas de enxertia óssea na estabilidade primária
Influência de diferentes técnicas de enxertia óssea na estabilidade primária Open
Objetivo: Revisar criticamente as evidências disponíveis sobre a influência de diferentes técnicas de enxertia óssea e preparo do leito na estabilidade primária de implantes dentários. Métodos: Revisão narrativa baseada em ensaios clínicos…
View article: INFLUÊNCIA DE DIFERENTES TÉCNICAS DE ENXERTIA ÓSSEA NA ESTABILIDADE PRIMÁRIA
INFLUÊNCIA DE DIFERENTES TÉCNICAS DE ENXERTIA ÓSSEA NA ESTABILIDADE PRIMÁRIA Open
Objetivo: Revisar criticamente as evidências disponíveis sobre a influência de diferentes técnicas de enxertia óssea e preparo do leito na estabilidade primária de implantes dentários. Métodos: Revisão narrativa baseada em ensaios clínicos…
View article: Sensitive dLight for imaging broad-spectrum dopamine events across brain regions
Sensitive dLight for imaging broad-spectrum dopamine events across brain regions Open
Dopaminergic neurons modulate movement, motivation, and learning by dynamically regulating dopamine release across distributed neural circuits. However, existing genetically encoded dopamine sensors lack the sensitivity and resolution to c…
View article: Robotics in Breast Surgery: Current Advantages, Disadvantages, and Applications
Robotics in Breast Surgery: Current Advantages, Disadvantages, and Applications Open
View article: Adaptive changes of cholinergic projections to the nucleus accumbens bidirectionally mediate cocaine reinforcing effects
Adaptive changes of cholinergic projections to the nucleus accumbens bidirectionally mediate cocaine reinforcing effects Open
The laterodorsal tegmentum (LDT) sends critical inputs to distinct reward circuit regions, including the nucleus accumbens (NAc), but their functional role in addiction-related behaviors remains underexplored. Here, we demonstrate that LDT…
View article: Chronic stress and cytogenesis ablation disrupt hippocampal neuron connectivity, with fluoxetine restoring function with sex-specific effects
Chronic stress and cytogenesis ablation disrupt hippocampal neuron connectivity, with fluoxetine restoring function with sex-specific effects Open
Hippocampal Adult-Born neurons (hABNs) play a critical role in maintaining brain homeostasis, exhibiting unique properties during their maturation. The absence of hABNs impacts surrounding neuronal networks, but the mechanisms are not full…
View article: Dermatite de Fralda em Lactentes: Fatores Desencadeantes, Abordagem Terapêutica e Medidas Preventivas
Dermatite de Fralda em Lactentes: Fatores Desencadeantes, Abordagem Terapêutica e Medidas Preventivas Open
A dermatite de fralda é uma condição comum em lactentes, resultante de uma combinação de fatores irritativos e infecciosos na região coberta pela fralda. Este artigo de revisão tem como objetivo discutir a fisiopatologia, causas principais…
View article: Prevalência da cirrose hepática não alcoólica em pacientes com obesidade: revisão integrativa e análise de dados do SIH/SUS
Prevalência da cirrose hepática não alcoólica em pacientes com obesidade: revisão integrativa e análise de dados do SIH/SUS Open
A cirrose hepática não alcoólica tem se destacado como uma das principais complicações da Doença Hepática Gordurosa Não Alcoólica (DHGNA), especialmente em indivíduos com obesidade, configurando-se como um problema de saúde pública em expa…
View article: Saúde mental no puerpério: principais transtornos e seus impactos na saúde materna e no desenvolvimento infantil
Saúde mental no puerpério: principais transtornos e seus impactos na saúde materna e no desenvolvimento infantil Open
O período puerperal envolve intensas alterações hormonais, imunológicas e emocionais, que aumentam a vulnerabilidade da mulher a transtornos psiquiátricos, como depressão, ansiedade, TOC e psicose pós-parto. Fatores como a queda do estrogê…
View article: Dynamic representation of appetitive and aversive stimuli in nucleus accumbens shell D1- and D2-medium spiny neurons
Dynamic representation of appetitive and aversive stimuli in nucleus accumbens shell D1- and D2-medium spiny neurons Open
View article: CIRCO (CIRCUITO INTERDISCIPLINAR DE REABILITAÇÃO E CONSCIÊNCIA CORPORAL): UMA ABORDAGEM EFICAZ CONTRA POLIFARMÁCIA E POLINTERNAÇÃO EM IDOSOS
CIRCO (CIRCUITO INTERDISCIPLINAR DE REABILITAÇÃO E CONSCIÊNCIA CORPORAL): UMA ABORDAGEM EFICAZ CONTRA POLIFARMÁCIA E POLINTERNAÇÃO EM IDOSOS Open
O aumento da expectativa de vida e a consequente transição demográfica têm resultado em um crescimento exponencial da população idosa, tornando imperativa a implementação de estratégias de saúde que minimizem os impactos da polifarmácia e …
View article: Sorting Nexin 27 Neuronal Silencing Impacts Hippocampal and Dopaminergic Circuits relevant for Cognitive Function
Sorting Nexin 27 Neuronal Silencing Impacts Hippocampal and Dopaminergic Circuits relevant for Cognitive Function Open
View article: CONCILIAÇÃO JUDICIAL ENTRE LITIGANTES EVENTUAIS E REPETITIVOS NAS RELAÇÕES DE CONSUMO
CONCILIAÇÃO JUDICIAL ENTRE LITIGANTES EVENTUAIS E REPETITIVOS NAS RELAÇÕES DE CONSUMO Open
A pesquisa analisa a eficácia da conciliação judicial em conflitos de consumo, com foco em litígios entre grandes corporações e consumidores considerados eventuais litigantes. O problema central investigado é se a conciliação pode ser um m…
View article: PAPEL DA CONSTITUIÇÃO BRASILEIRA DE 1988 NA REGULAMENTAÇÃO DA ORDEM ECONÔMICA E DAS RELAÇÕES DE CONSUMO
PAPEL DA CONSTITUIÇÃO BRASILEIRA DE 1988 NA REGULAMENTAÇÃO DA ORDEM ECONÔMICA E DAS RELAÇÕES DE CONSUMO Open
A Constituição Federal de 1988 desempenha um papel fundamental na estruturação da ordem econômica brasileira e na proteção dos direitos dos consumidores, representando um marco histórico que reflete a preocupação do Estado em promover um a…
View article: Unveiling the molecular landscape of cognitive aging: insights from polygenic risk scores, DNA methylation, and gene expression
Unveiling the molecular landscape of cognitive aging: insights from polygenic risk scores, DNA methylation, and gene expression Open
Background Aging represents a significant risk factor for the occurrence of cerebral small vessel disease, associated with white matter (WM) lesions, and to age-related cognitive alterations, though the precise mechanisms remain largely un…
View article: In and Out of Criticality? State-Dependent Scaling in the Rat Visual Cortex
In and Out of Criticality? State-Dependent Scaling in the Rat Visual Cortex Open
The presumed proximity to a critical point is believed to endow the brain with scale-invariant statistics, which are thought to confer various functional advantages in terms of its information processing, storage, and transmission capabili…
View article: The mesopontine tegmentum in reward and aversion: From cellular heterogeneity to behaviour
The mesopontine tegmentum in reward and aversion: From cellular heterogeneity to behaviour Open
The mesopontine tegmentum, comprising the pedunculopontine tegmentum (PPN) and the laterodorsal tegmentum (LDT), is intricately connected to various regions of the basal ganglia, motor systems, and limbic systems. The PPN and LDT can regul…
View article: Physiological and behavioral contagion/buffering effects of chronic unpredictable stress in a socially enriched environment: A preliminary study
Physiological and behavioral contagion/buffering effects of chronic unpredictable stress in a socially enriched environment: A preliminary study Open
Rodents are sensitive to the emotional state of conspecifics. While the presence of affiliative social partners mitigates the physiological response to stressors (buffering), the partners of stressed individuals show behavioral and endocri…
View article: Early morphological and neurochemical changes of the bed nucleus of stria terminalis (BNST) in gestational protein-restricted male offspring
Early morphological and neurochemical changes of the bed nucleus of stria terminalis (BNST) in gestational protein-restricted male offspring Open
Background The bed nucleus of the stria terminalis (BNST) is a structure with a peculiar neurochemical composition involved in modulating anxietylike behavior and fear.
View article: Glial-restricted precursors stimulate endogenous cytogenesis and effectively recover emotional deficits in a model of cytogenesis ablation
Glial-restricted precursors stimulate endogenous cytogenesis and effectively recover emotional deficits in a model of cytogenesis ablation Open
View article: SNX27: A trans-species cognitive modulator with implications for anxiety and stress susceptibility
SNX27: A trans-species cognitive modulator with implications for anxiety and stress susceptibility Open
Sorting Nexin 27 (SNX27) is a brain-enriched endosome-associated cargo adaptor that shapes excitatory control, being relevant for cognitive and reward processing, and for several neurological conditions. Despite this, SNX27's role in the n…
View article: Dynamic representation of appetitive and aversive stimuli in nucleus accumbens shell D1- and D2-medium spiny neurons
Dynamic representation of appetitive and aversive stimuli in nucleus accumbens shell D1- and D2-medium spiny neurons Open
The nucleus accumbens (NAc) is a key brain region for motivated behaviors, yet how distinct neuronal populations encode appetitive or aversive stimuli remains undetermined. Using microendoscopic calcium imaging, we tracked NAc shell D1- or…
View article: Nucleus accumbens neurons dynamically respond to appetitive and aversive associative learning
Nucleus accumbens neurons dynamically respond to appetitive and aversive associative learning Open
To survive, individuals must learn to associate cues in the environment with emotionally relevant outcomes. This association is partially mediated by the nucleus accumbens (NAc), a key brain region of the reward circuit that is mainly comp…
View article: Cecal Volvulus in an Elderly Woman: A Rare Cause of Bowel Obstruction
Cecal Volvulus in an Elderly Woman: A Rare Cause of Bowel Obstruction Open
View article: Negative associations between maternal prenatal hair cortisol and child socioemotional problems
Negative associations between maternal prenatal hair cortisol and child socioemotional problems Open
View article: State-dependent complexity of the local field potential in the primary visual cortex
State-dependent complexity of the local field potential in the primary visual cortex Open
The local field potential (LFP) is as a measure of the combined activity of neurons within a region of brain tissue. While biophysical modeling schemes for LFP in cortical circuits are well established, there is a paramount lack of underst…
View article: A novel perspective on the role of nucleus accumbens neurons in encoding associative learning
A novel perspective on the role of nucleus accumbens neurons in encoding associative learning Open
The nucleus accumbens (NAc) has been considered a key brain region for encoding reward/aversion and cue–outcome associations. These processes are encoded by medium spiny neurons that express either dopamine receptor D1 (D1‐MSNs) or D2 (D2‐…