Alexandre Caron
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View article: Integration of Multiomic and Multi-phenotypic Data Identifies Biological Pathways Associated with Physical Fitness
Integration of Multiomic and Multi-phenotypic Data Identifies Biological Pathways Associated with Physical Fitness Open
Unraveling the complex associations between human phenotypes and molecular pathways can pave the way to improved health and performance, but faces a fundamental challenge: the measurable genes, proteins, and metabolites vastly outnumber th…
View article: Revolutionary Medicine in the Next Decade
Revolutionary Medicine in the Next Decade Open
The next decade will mark a turning point in the history of medicine, as multiple technological and scientific advances converge to reshape how disease is understood, prevented, and treated. Personalized and precision medicine, enabled by …
View article: Using the microbiota to study connectivity at human–animal interfaces
Using the microbiota to study connectivity at human–animal interfaces Open
Interfaces between humans, livestock, and wildlife, mediated by the environment, are critical points for the transmission and emergence of infectious pathogens and call for leveraging the One Health approach to understanding disease transm…
View article: BioTIME 2.0: Expanding and Improving a Database of Biodiversity Time Series
BioTIME 2.0: Expanding and Improving a Database of Biodiversity Time Series Open
Motivation Here, we make available a second version of the BioTIME database, which compiles records of abundance estimates for species in sample events of ecological assemblages through time. The updated version expands version 1.0 of the …
View article: Building the future One Health workforce in Eastern and Southern Africa: Gaps and opportunities
Building the future One Health workforce in Eastern and Southern Africa: Gaps and opportunities Open
The Quadripartite comprised of the Food and Agriculture Organization (FAO), World Health Organization (WHO), World Organisation for Animal Health (WOAH), the United Nations Environment Program (UNEP), and the One Health High Level Expert P…
View article: Structural insight into the cGAS active site explains differences between therapeutically relevant species
Structural insight into the cGAS active site explains differences between therapeutically relevant species Open
Cyclic GMP-AMP synthase (cGAS) is an intracellular sensor of double-stranded DNA that triggers a pro-inflammatory response upon binding. The interest in cGAS as a drug discovery target has increased substantially over the past decade due t…
View article: Revealing year-round activity of cave-dwelling insectivorous bats with a sonotype classifier in data-deficient areas.
Revealing year-round activity of cave-dwelling insectivorous bats with a sonotype classifier in data-deficient areas. Open
Context: Bats are the only mammals who have conquered the skies and the leading mammals in terms of total biomass with the exception of humans and domestic mammals. However, the ecology of many bat species is still unknown, especially in p…
View article: Preferred livestock interventions for small-scale farmers in the Great Limpopo Transfrontier Conservation Area: a demand-driven and participatory approach
Preferred livestock interventions for small-scale farmers in the Great Limpopo Transfrontier Conservation Area: a demand-driven and participatory approach Open
In southern Africa, residents of Transfrontier Conservation Areas (TFCAs), devoted to biodiversity conservation and local development and well-being, practice small-scale farming in semi-arid environments constrained by the presence of pro…
View article: Bridging gaps and leveraging opportunities for One Health: Feedback from the 8th World One Health Congress
Bridging gaps and leveraging opportunities for One Health: Feedback from the 8th World One Health Congress Open
We attended the 8th WOHC between the 20th and 23rd of September 2024 in Cape Town, South Africa and we provide here our feedback with a specific perspective on the policy implications. The One Health approach still needs to go beyond disea…
View article: Habitat sharing and interspecies interactions in caves used by bats in the Republic of Congo
Habitat sharing and interspecies interactions in caves used by bats in the Republic of Congo Open
Bats play key roles in ecosystem functions and provide services to human populations. There is a need to protect bat populations and to mitigate the risks associated with pathogen spillover. Caves are key habitats for many bat species, whi…
View article: Socio-economic and ecological factors linked to the adoption of foreign livestock breeds by Zimbabwean smallholders farmers in the Great Limpopo Transfrontier Conservation Area
Socio-economic and ecological factors linked to the adoption of foreign livestock breeds by Zimbabwean smallholders farmers in the Great Limpopo Transfrontier Conservation Area Open
Background: In rural areas in Africa, the productivity of small-scale livestock systems is low. Development programmes aim to increase productivity using technical innovations, including the introduction of foreign breeds. The level of ado…
View article: Video of rusty‐spotted genets consuming bats and other prey: Behaviors observed and eco‐epidemiological considerations
Video of rusty‐spotted genets consuming bats and other prey: Behaviors observed and eco‐epidemiological considerations Open
Following the implementation of a camera trap‐monitoring protocol of interactions between cave bats and wildlife in the Republic of Congo, we identified sustained rusty‐spotted genet ( Genetta maculata ) activity in Boundou cave. This cave…
View article: Spatial mechanistic modelling to simulate movements and contacts between wildlife and livestock in Southern Africa
Spatial mechanistic modelling to simulate movements and contacts between wildlife and livestock in Southern Africa Open
International audience
View article: Advancing One Health Capacities in Mozambique: A Case Study of COHESA
Advancing One Health Capacities in Mozambique: A Case Study of COHESA Open
One Health (OH) concept recognizes the interconnectedness of human, animal, environmental and plant health, and the need for collaboration across these sectors to address health challenges. Mozambique is a southern African country and face…
View article: Assessing One Health in Zambia: Necessity, Application and Operationalisation
Assessing One Health in Zambia: Necessity, Application and Operationalisation Open
“Capacitating One Health in Eastern and Southern Africa (COHESA)” aims at facilitating the ownership, development, adoption, uptake and adaptation of One Health (OH) solutions in Eastern and Southern African region. Further, COHESA develop…
View article: Status of One Health Implementation in Botswana
Status of One Health Implementation in Botswana Open
One Health (OH) is a collaborative, multisector and transdisciplinary approach to mitigate various issues related to the health of animals, plants, humans and ecosystems and their interactions for optimal health. In Botswana, the main goal…
View article: One Health Landscape in Zimbabwe: Current Status, Challenges and Opportunities for Institutionalisation
One Health Landscape in Zimbabwe: Current Status, Challenges and Opportunities for Institutionalisation Open
A baseline assessment was conducted to describe the current landscape and opportunities for operationalising One Health (OH) in Zimbabwe. A desktop review, focus group discussion and key informant interviews were used to collect data. A pr…
View article: Namibia OH Landscape: Challenges, Opportunities and Collaborative Strategies
Namibia OH Landscape: Challenges, Opportunities and Collaborative Strategies Open
The Capacitating One Health in Eastern and Southern Africa (COHESA) initiative fosters research and innovation that facilitates seamless integration, customization, and operationalization of One Health (OH)- focused solutions. It is spearh…
View article: Towards Institutionalization of One Health in Eastern and Southern Africa
Towards Institutionalization of One Health in Eastern and Southern Africa Open
The integration of One Health (OH) approaches, principles, and ethos within international organizations and public sectors’ national health and environmental structures is a long process that requires both institutionalization and operatio…
View article: Continent-wide genomic analysis of the African buffalo (<i>Syncerus caffer</i>)
Continent-wide genomic analysis of the African buffalo (<i>Syncerus caffer</i>) Open
The African buffalo ( Syncerus caffer ) is a wild bovid with a historical distribution across much of sub-Saharan Africa. Genomic analysis can provide insights into the evolutionary history of the species, and the key selective pressures s…
View article: Futures of the African Buffalo
Futures of the African Buffalo Open
International audience
View article: Knowns and Unknowns in African Buffalo Ecology and Management
Knowns and Unknowns in African Buffalo Ecology and Management Open
he African buffalo is one of the best-researched of all ungulate species even though it must give way to some North American deer species, an elephant-seal species and the red deer. The African buffalo had some monographs dedicated to it, …
View article: Ecology and Management of the African Buffalo
Ecology and Management of the African Buffalo Open
One of iconic Africa's Big Five, the African buffalo is the largest African bovine or antelope that occurs throughout most of sub-Sahara and in a wide range of ecosystems from savanna to rainforest. The African buffalo is also one of the m…
View article: African Buffalo Social Dynamics: What Is a Buffalo Herd?
African Buffalo Social Dynamics: What Is a Buffalo Herd? Open
Some aspects of the well-described planet- and satellite-like framework of, respectively, mixed herds and bachelor groups of buffalo recently were challenged. Associations of female buffalo are now considered more fluid than the initial id…
View article: Diseases
Diseases Open
Source Agritrop Cirad (https://agritrop.cirad.fr/608794/)
View article: African Buffalo and Colonial Cattle: Is ‘Systems Change’ the Best Future for Farming and Nature in Africa?
African Buffalo and Colonial Cattle: Is ‘Systems Change’ the Best Future for Farming and Nature in Africa? Open
Much of the narrative for land clearing of wildlife is historic and frequently blames buffalo for livestock diseases, a dogma perpetrated throughout colonial history and inherited by emerging African states after decolonization. A review o…
View article: Conservation Status of the African Buffalo: A Continent-Wide Assessment
Conservation Status of the African Buffalo: A Continent-Wide Assessment Open
This chapter presents the distribution, abundance patterns and trends of African buffalo in the 38 countries of its distribution area based on recent aerial and ground census data and feedback from field experts. For the period 2001–2021, …